FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893560206> ?p ?o ?g. }

• W2893560206 endingPage "13" @default.
• W2893560206 startingPage "1" @default.
• W2893560206 abstract "Gynura procumbens (GP) is a medicinal herb that has long been known as anti-inflammatory and antihyperglycaemic. Recently, this herbal extract has been associated with a profertility effect, suggesting its applicability in treating both diabetes and male infertility. In this study, the effects of GP aqueous extract (GPAE) on diabetic rats were investigated through evaluating testes histology and androgen hormone levels as well as the implantation sites of female rats on copulation with the treated male rats. Three dosages of GPAE were used (150, 300, and 450 mg/kg), and there were three control groups [normal, diabetic, and metformin-treated diabetic]. Testes histology, androgen hormone levels, and number of implantation sites of the GPAE-treated groups matched those of the normal group in contrast to the diabetic and metformin-treated diabetic controls. Sperm proteomics analysis identified 666 proteins, but only 88 were consistently found in all the control and 450-mg/kg GPAE-treated groups. Four proteins, including cysteine-rich secretory protein 1, carboxylesterase 5A, zona pellucida binding protein, and phosphatidylethanolamine-binding protein 1, were significantly upregulated with GPAE treatment compared with the diabetic control, matching the protein levels of the normal group. These proteins were mainly involved in sperm maturation, sperm capacitation, and sperm-egg interaction, suggesting that GP treatment was able to restore the fertility of male diabetic rats at molecular protein level. In conclusion, GP treatment effectively treats infertility of male diabetic rats, possibly through the upregulation of proteins related to sperm maturation and sperm-egg interaction." @default.
• W2893560206 created "2018-10-05" @default.
• W2893560206 creator A5015310539 @default.
• W2893560206 creator A5034080219 @default.
• W2893560206 creator A5072982731 @default.
• W2893560206 date "2018-09-30" @default.
• W2893560206 modified "2023-10-16" @default.
• W2893560206 title "<i>Gynura procumbens </i>Improved Fertility of Diabetic Rats: Preliminary Study of Sperm Proteomic" @default.
• W2893560206 cites W1162287743 @default.
• W2893560206 cites W1489528392 @default.
• W2893560206 cites W1800007752 @default.
• W2893560206 cites W1977656954 @default.
• W2893560206 cites W1977970813 @default.
• W2893560206 cites W1986193553 @default.
• W2893560206 cites W1991069718 @default.
• W2893560206 cites W1996257643 @default.
• W2893560206 cites W2006461819 @default.
• W2893560206 cites W2024420929 @default.
• W2893560206 cites W2027827512 @default.
• W2893560206 cites W2048588885 @default.
• W2893560206 cites W2048667167 @default.
• W2893560206 cites W2049511442 @default.
• W2893560206 cites W2052710582 @default.
• W2893560206 cites W2067998485 @default.
• W2893560206 cites W2069379444 @default.
• W2893560206 cites W2070459523 @default.
• W2893560206 cites W2078947946 @default.
• W2893560206 cites W2086646917 @default.
• W2893560206 cites W2089313341 @default.
• W2893560206 cites W2095975048 @default.
• W2893560206 cites W2098514896 @default.
• W2893560206 cites W2128158877 @default.
• W2893560206 cites W2137654127 @default.
• W2893560206 cites W2147649232 @default.
• W2893560206 cites W2463195069 @default.
• W2893560206 cites W2760968640 @default.
• W2893560206 cites W2774247544 @default.
• W2893560206 cites W4235368586 @default.
• W2893560206 doi "https://doi.org/10.1155/2018/9201539" @default.
• W2893560206 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6186343" @default.
• W2893560206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30363997" @default.
• W2893560206 hasPublicationYear "2018" @default.
• W2893560206 type Work @default.
• W2893560206 sameAs 2893560206 @default.
• W2893560206 citedByCount "7" @default.
• W2893560206 countsByYear W28935602062019 @default.
• W2893560206 countsByYear W28935602062020 @default.
• W2893560206 countsByYear W28935602062021 @default.
• W2893560206 countsByYear W28935602062022 @default.
• W2893560206 crossrefType "journal-article" @default.
• W2893560206 hasAuthorship W2893560206A5015310539 @default.
• W2893560206 hasAuthorship W2893560206A5034080219 @default.
• W2893560206 hasAuthorship W2893560206A5072982731 @default.
• W2893560206 hasBestOaLocation W28935602061 @default.
• W2893560206 hasConcept C104317684 @default.
• W2893560206 hasConcept C123765429 @default.
• W2893560206 hasConcept C126322002 @default.
• W2893560206 hasConcept C127561419 @default.
• W2893560206 hasConcept C134018914 @default.
• W2893560206 hasConcept C16685009 @default.
• W2893560206 hasConcept C2777338322 @default.
• W2893560206 hasConcept C2777688143 @default.
• W2893560206 hasConcept C2777911890 @default.
• W2893560206 hasConcept C2779234561 @default.
• W2893560206 hasConcept C2779279991 @default.
• W2893560206 hasConcept C2780323712 @default.
• W2893560206 hasConcept C2781087480 @default.
• W2893560206 hasConcept C54355233 @default.
• W2893560206 hasConcept C55493867 @default.
• W2893560206 hasConcept C555293320 @default.
• W2893560206 hasConcept C71315377 @default.
• W2893560206 hasConcept C71924100 @default.
• W2893560206 hasConcept C86803240 @default.
• W2893560206 hasConceptScore W2893560206C104317684 @default.
• W2893560206 hasConceptScore W2893560206C123765429 @default.
• W2893560206 hasConceptScore W2893560206C126322002 @default.
• W2893560206 hasConceptScore W2893560206C127561419 @default.
• W2893560206 hasConceptScore W2893560206C134018914 @default.
• W2893560206 hasConceptScore W2893560206C16685009 @default.
• W2893560206 hasConceptScore W2893560206C2777338322 @default.
• W2893560206 hasConceptScore W2893560206C2777688143 @default.
• W2893560206 hasConceptScore W2893560206C2777911890 @default.
• W2893560206 hasConceptScore W2893560206C2779234561 @default.
• W2893560206 hasConceptScore W2893560206C2779279991 @default.
• W2893560206 hasConceptScore W2893560206C2780323712 @default.
• W2893560206 hasConceptScore W2893560206C2781087480 @default.
• W2893560206 hasConceptScore W2893560206C54355233 @default.
• W2893560206 hasConceptScore W2893560206C55493867 @default.
• W2893560206 hasConceptScore W2893560206C555293320 @default.
• W2893560206 hasConceptScore W2893560206C71315377 @default.
• W2893560206 hasConceptScore W2893560206C71924100 @default.
• W2893560206 hasConceptScore W2893560206C86803240 @default.
• W2893560206 hasFunder F4320322699 @default.
• W2893560206 hasLocation W28935602061 @default.
• W2893560206 hasLocation W28935602062 @default.
• W2893560206 hasLocation W28935602063 @default.
• W2893560206 hasLocation W28935602064 @default.
• W2893560206 hasLocation W28935602065 @default.

• next