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- W2893580777 abstract "Established surgical scores have limitations in delineating risk among candidates for transcatheter aortic valve implantation (TAVI). Assessment of frailty might help to estimate the mortality risk and identify patients likely to benefit from treatment. The aim of the study was to develop a frailty score to guide the decision for TAVI.We conducted a prospective observational study in patients ≥70 years referred for TAVI during 2011-15. A Heart Team had declined the patients for open heart surgery due to high risk but accepted them for TAVI. Prior to the procedure, a geriatric assessment (GA) was performed. Based on this, an 8-element frailty score with a 0-9 (least frail-most frail) scale was developed. A total of 142 patients, 54% women, mean age 83 (standard deviation 4) years, with severe and symptomatic aortic stenosis were assessed. All-cause 2 year mortality was 11%. The novel GA frailty score predicted 2-year mortality in Cox analyses, also when adjusted for age, gender, and logistic EuroSCORE [hazard ratio (HR) 1.75, 95% confidence interval (CI): 1.28-2.42, P < 0.001]. A receiver operating characteristic (ROC) curve analysis indicated that a GA frailty score cut-off at ≥4 predicted 2-year mortality with a specificity of 80% (95% CI: 73-86%) and a sensitivity of 60% (95% CI: 36-80%). The area under the curve was 0.81 (95% CI 0.71-0.90).A novel 8-element GA frailty score identified gradations in survival in patients declined for open heart surgery. Patients with higher GA frailty scores had significantly higher 2-year mortality after TAVI." @default.
- W2893580777 created "2018-10-05" @default.
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- W2893580777 date "2018-10-31" @default.
- W2893580777 modified "2023-10-13" @default.
- W2893580777 title "A novel geriatric assessment frailty score predicts 2-year mortality after transcatheter aortic valve implantation" @default.
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- W2893580777 cites W1847168837 @default.
- W2893580777 cites W1856216806 @default.
- W2893580777 cites W1882254093 @default.
- W2893580777 cites W1964471691 @default.
- W2893580777 cites W1970195980 @default.
- W2893580777 cites W1975019358 @default.
- W2893580777 cites W1991070759 @default.
- W2893580777 cites W2000445173 @default.
- W2893580777 cites W2006617902 @default.
- W2893580777 cites W2008854521 @default.
- W2893580777 cites W2011155516 @default.
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- W2893580777 cites W2028094330 @default.
- W2893580777 cites W2036228404 @default.
- W2893580777 cites W2052139208 @default.
- W2893580777 cites W2053215165 @default.
- W2893580777 cites W2058161128 @default.
- W2893580777 cites W2067840329 @default.
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- W2893580777 cites W2164059021 @default.
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- W2893580777 cites W2596816418 @default.
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- W2893580777 doi "https://doi.org/10.1093/ehjqcco/qcy044" @default.
- W2893580777 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6440438" @default.
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