FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W289359787> ?p ?o ?g. }

• W289359787 endingPage "7895" @default.
• W289359787 startingPage "7891" @default.
• W289359787 abstract "miRNA-22 (miR-22) has been showed to involve in a variety of cancers; however, the association between miR-22 expression level and the prognosis of osteosarcoma is also poorly unknown. Fifty-two patients with surgically resected paired osteosarcoma and non-neoplastic disease between 2008 and 2014 were involved in this study. Real-time PCR was performed to examine the expression level of miR-22 in osteosarcoma tissues and noncancerous bone tissues. Then the association between miR-22 expression and clinical-pathological parameters were further evaluated. Kaplan-Meier analysis and Cox proportional hazards regression models were explored to reveal the correlations of miR-22 expression with survival of patients. The results indicated that miR-22 was downregulated in osteosarcoma tissues in comparison with noncancerous bone tissues. In addition, there is statistically significance between miR-22 expression level and recurrence, metastasis, and chemotherapy response. The patients with lower miR-22 expression level had both poorer overall survival and disease-free survival. The multivariant analysis revealed that the miR-22 expression level and metastasis status are independent prognosis factors for osteosarcoma. In conclusion, miR-22 was downregulated in osteosarcoma and its expression level was correlated with a variety of important clinical-pathological parameters. Moreover, miR-22 may serve as a promising biomarker for predicting the prognosis of osteosarcoma." @default.
• W289359787 created "2016-06-24" @default.
• W289359787 creator A5007264357 @default.
• W289359787 creator A5011573172 @default.
• W289359787 creator A5017588828 @default.
• W289359787 creator A5042026897 @default.
• W289359787 creator A5047297311 @default.
• W289359787 date "2015-05-08" @default.
• W289359787 modified "2023-10-02" @default.
• W289359787 title "Downregulation of miR-22 acts as an unfavorable prognostic biomarker in osteosarcoma" @default.
• W289359787 cites W1550321285 @default.
• W289359787 cites W1965062762 @default.
• W289359787 cites W1967915040 @default.
• W289359787 cites W1972694236 @default.
• W289359787 cites W1977098496 @default.
• W289359787 cites W1980840305 @default.
• W289359787 cites W1991919948 @default.
• W289359787 cites W2003334487 @default.
• W289359787 cites W2009143398 @default.
• W289359787 cites W2032030355 @default.
• W289359787 cites W2045914559 @default.
• W289359787 cites W2046375626 @default.
• W289359787 cites W2053855502 @default.
• W289359787 cites W2064600697 @default.
• W289359787 cites W2067529935 @default.
• W289359787 cites W2078576279 @default.
• W289359787 cites W2078786772 @default.
• W289359787 cites W2092059355 @default.
• W289359787 cites W2098158938 @default.
• W289359787 cites W2110783968 @default.
• W289359787 cites W2113296997 @default.
• W289359787 cites W2115094397 @default.
• W289359787 cites W2137622697 @default.
• W289359787 cites W2148842420 @default.
• W289359787 cites W2150740663 @default.
• W289359787 cites W2156118453 @default.
• W289359787 cites W2168912846 @default.
• W289359787 cites W2169610619 @default.
• W289359787 cites W2699220065 @default.
• W289359787 doi "https://doi.org/10.1007/s13277-015-3379-1" @default.
• W289359787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25953260" @default.
• W289359787 hasPublicationYear "2015" @default.
• W289359787 type Work @default.
• W289359787 sameAs 289359787 @default.
• W289359787 citedByCount "22" @default.
• W289359787 countsByYear W2893597872015 @default.
• W289359787 countsByYear W2893597872016 @default.
• W289359787 countsByYear W2893597872017 @default.
• W289359787 countsByYear W2893597872018 @default.
• W289359787 countsByYear W2893597872019 @default.
• W289359787 countsByYear W2893597872020 @default.
• W289359787 countsByYear W2893597872022 @default.
• W289359787 countsByYear W2893597872023 @default.
• W289359787 crossrefType "journal-article" @default.
• W289359787 hasAuthorship W289359787A5007264357 @default.
• W289359787 hasAuthorship W289359787A5011573172 @default.
• W289359787 hasAuthorship W289359787A5017588828 @default.
• W289359787 hasAuthorship W289359787A5042026897 @default.
• W289359787 hasAuthorship W289359787A5047297311 @default.
• W289359787 hasConcept C104317684 @default.
• W289359787 hasConcept C10515644 @default.
• W289359787 hasConcept C121608353 @default.
• W289359787 hasConcept C126322002 @default.
• W289359787 hasConcept C127561419 @default.
• W289359787 hasConcept C142724271 @default.
• W289359787 hasConcept C143998085 @default.
• W289359787 hasConcept C145059251 @default.
• W289359787 hasConcept C204232928 @default.
• W289359787 hasConcept C207886595 @default.
• W289359787 hasConcept C2776035513 @default.
• W289359787 hasConcept C2777760704 @default.
• W289359787 hasConcept C2779013556 @default.
• W289359787 hasConcept C2779134260 @default.
• W289359787 hasConcept C2781197716 @default.
• W289359787 hasConcept C502942594 @default.
• W289359787 hasConcept C50382708 @default.
• W289359787 hasConcept C55493867 @default.
• W289359787 hasConcept C63363279 @default.
• W289359787 hasConcept C71924100 @default.
• W289359787 hasConcept C86803240 @default.
• W289359787 hasConceptScore W289359787C104317684 @default.
• W289359787 hasConceptScore W289359787C10515644 @default.
• W289359787 hasConceptScore W289359787C121608353 @default.
• W289359787 hasConceptScore W289359787C126322002 @default.
• W289359787 hasConceptScore W289359787C127561419 @default.
• W289359787 hasConceptScore W289359787C142724271 @default.
• W289359787 hasConceptScore W289359787C143998085 @default.
• W289359787 hasConceptScore W289359787C145059251 @default.
• W289359787 hasConceptScore W289359787C204232928 @default.
• W289359787 hasConceptScore W289359787C207886595 @default.
• W289359787 hasConceptScore W289359787C2776035513 @default.
• W289359787 hasConceptScore W289359787C2777760704 @default.
• W289359787 hasConceptScore W289359787C2779013556 @default.
• W289359787 hasConceptScore W289359787C2779134260 @default.
• W289359787 hasConceptScore W289359787C2781197716 @default.
• W289359787 hasConceptScore W289359787C502942594 @default.
• W289359787 hasConceptScore W289359787C50382708 @default.
• W289359787 hasConceptScore W289359787C55493867 @default.

• next