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• W2893598894 endingPage "12" @default.
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• W2893598894 abstract "The development of new biomaterials to be used in tissue engineering applications is creating new solutions for a range of healthcare problems. The trend in biomaterials research has shifted from biocompatible “immune-evasive” biomaterials to “immune-interactive” materials that modulate the inflammatory response supporting implant integration as well as improving healing and tissue regeneration. Inflammasomes are large intracellular multiprotein complexes that are key players in host defence during innate immune responses and assemble after recognition of pathogens or danger signals. The process of biomaterial implantation causes injury to tissues that will consequently release danger signals that could be sensed by the inflammasome. There are increasing evidences that the inflammasome has a role in several inflammatory processes, from pathogen clearance to chronic inflammation or tissue repair. Thus, modulation of the inflammasome activity appears as an important target in the development of effective approaches in regenerative medicine. In this review, we discuss the main points of the current understanding on the host response to implanted biomaterials and how the paradigm of “immune-evasive” biomaterials has shifted over the last years; the significance of the inflammasome in the inflammatory response to biomaterials; and the growing idea that the immune system is of key importance in an effective tissue repair and regeneration. We herein discuss the main points of the current understanding on the host response to implanted biomaterials and how the paradigm of “immune-evasive” biomaterials has shifted to “immune-interactive” over the last years; the significance of the inflammasome in the inflammatory response to biomaterials; and the growing idea that the immune system is of key importance in an effective tissue repair and regeneration, supporting the emerging concept of Regenerative Immunology. The inflammasome is a recent and central concept in immunology research. Since the beginning of this century the inflammasome is viewed as key platform of the innate immune response. We believe that, successful modulation of the inflammasome activity will become a milestone in the fields of tissue engineering and regenerative medicine." @default.
• W2893598894 created "2018-10-05" @default.
• W2893598894 creator A5002285119 @default.
• W2893598894 creator A5008112495 @default.
• W2893598894 creator A5016617030 @default.
• W2893598894 creator A5026602304 @default.
• W2893598894 creator A5082446277 @default.
• W2893598894 date "2019-01-01" @default.
• W2893598894 modified "2023-10-17" @default.
• W2893598894 title "The inflammasome in host response to biomaterials: Bridging inflammation and tissue regeneration" @default.
• W2893598894 cites W1482850806 @default.
• W2893598894 cites W1506582172 @default.
• W2893598894 cites W1529674879 @default.
• W2893598894 cites W1536345883 @default.
• W2893598894 cites W1575890745 @default.
• W2893598894 cites W1576545864 @default.
• W2893598894 cites W1601517895 @default.
• W2893598894 cites W1797422316 @default.
• W2893598894 cites W1885826309 @default.
• W2893598894 cites W1889359478 @default.
• W2893598894 cites W1965130745 @default.
• W2893598894 cites W1966079664 @default.
• W2893598894 cites W1966684175 @default.
• W2893598894 cites W1966910055 @default.
• W2893598894 cites W1971601359 @default.
• W2893598894 cites W1973135566 @default.
• W2893598894 cites W1974744480 @default.
• W2893598894 cites W1977159891 @default.
• W2893598894 cites W1982041308 @default.
• W2893598894 cites W1986731647 @default.
• W2893598894 cites W1992102409 @default.
• W2893598894 cites W1995063875 @default.
• W2893598894 cites W2004536682 @default.
• W2893598894 cites W2005575042 @default.
• W2893598894 cites W2008565536 @default.
• W2893598894 cites W2015289974 @default.
• W2893598894 cites W2021623392 @default.
• W2893598894 cites W2024094193 @default.
• W2893598894 cites W2027280434 @default.
• W2893598894 cites W2031041031 @default.
• W2893598894 cites W2031084334 @default.
• W2893598894 cites W2041591721 @default.
• W2893598894 cites W2042301629 @default.
• W2893598894 cites W2045561438 @default.
• W2893598894 cites W2048009024 @default.
• W2893598894 cites W2049407962 @default.
• W2893598894 cites W2050449334 @default.
• W2893598894 cites W2054472394 @default.
• W2893598894 cites W2055348159 @default.
• W2893598894 cites W2060119002 @default.
• W2893598894 cites W2061609938 @default.
• W2893598894 cites W2065330071 @default.
• W2893598894 cites W2070319203 @default.
• W2893598894 cites W2070855360 @default.
• W2893598894 cites W2077332962 @default.
• W2893598894 cites W2077796307 @default.
• W2893598894 cites W2079790969 @default.
• W2893598894 cites W2079882002 @default.
• W2893598894 cites W2084751257 @default.
• W2893598894 cites W2089503694 @default.
• W2893598894 cites W2090609282 @default.
• W2893598894 cites W2093839463 @default.
• W2893598894 cites W2093928471 @default.
• W2893598894 cites W2094365218 @default.
• W2893598894 cites W2094629012 @default.
• W2893598894 cites W2100748575 @default.
• W2893598894 cites W2103722820 @default.
• W2893598894 cites W2104667669 @default.
• W2893598894 cites W2105415546 @default.
• W2893598894 cites W2107461742 @default.
• W2893598894 cites W2109173007 @default.
• W2893598894 cites W2113186517 @default.
• W2893598894 cites W2113485094 @default.
• W2893598894 cites W2114769428 @default.
• W2893598894 cites W2120699390 @default.
• W2893598894 cites W2122405246 @default.
• W2893598894 cites W2123431656 @default.
• W2893598894 cites W2127130381 @default.
• W2893598894 cites W2127176298 @default.
• W2893598894 cites W2128190429 @default.
• W2893598894 cites W2130940574 @default.
• W2893598894 cites W2131082021 @default.
• W2893598894 cites W2140637559 @default.
• W2893598894 cites W2143119237 @default.
• W2893598894 cites W2149466673 @default.
• W2893598894 cites W2150320891 @default.
• W2893598894 cites W2150594596 @default.
• W2893598894 cites W2153454088 @default.
• W2893598894 cites W2158500407 @default.
• W2893598894 cites W2167815042 @default.
• W2893598894 cites W2171793224 @default.
• W2893598894 cites W2210680772 @default.
• W2893598894 cites W2229049611 @default.
• W2893598894 cites W2254807163 @default.
• W2893598894 cites W2276788395 @default.
• W2893598894 cites W2301044272 @default.
• W2893598894 cites W2342254944 @default.
• W2893598894 cites W2343832243 @default.

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