FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893603452> ?p ?o ?g. }

• W2893603452 abstract "Inherited leukodystrophies are a group of diseases affecting central nervous system myelin that lead to death or significant health problems. Although for most leukodystrophies there are no curative treatments, for a handful of diseases hematopoietic stem cell transplantation (HSCT; bone marrow transplant) can stop disease progression, and if initiated in a timely fashion, prevent many or all neurologic and other systems involvement. However, HSCT is a complex procedure with significant morbidity and mortality risks. The study goal was to determine whether HSCT was being more widely used outside of those leukodystrophies for which HSCT is typically employed. The authors conducted a 2-year retrospective review of HSCT performed across the United States in 51 children’s hospitals that are part of the Pediatric Health Information System. The authors screened for 10th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) codes for leukodystrophies in which HSCT is “nonstandard,” including sphingolipidoses, Fabry disease, Gaucher disease, and Niemann-Pick disease, and excluded patients who had ICD-10 codes for leukodystrophies that are HSCT candidates, specifically X-linked adrenoleukodystrophy, metachromatic leukodystrophy, Krabbe disease, and Hurler disease. The authors identified 91 patients (from a total cohort of 937) with one of the nonstandard leukodystrophies who had HSCT. HSCT was performed at 20 of the hospitals, with the majority performed at only 6 hospitals. Average costs ($786 846) per patient were more than 6 times higher than patients who did not have HSCT. The data show that an unexpectedly large number of leukodystrophy patients are receiving transplants for conditions in which HSCT is not typically used, and which are associated with high medical costs." @default.
• W2893603452 created "2018-10-05" @default.
• W2893603452 creator A5021803974 @default.
• W2893603452 creator A5047907963 @default.
• W2893603452 creator A5065566020 @default.
• W2893603452 date "2018-09-28" @default.
• W2893603452 modified "2023-09-26" @default.
• W2893603452 title "Scope and Burden of Non–Standard of Care Hematopoietic Stem Cell Transplantation in Pediatric Leukodystrophy Patients" @default.
• W2893603452 cites W1576731495 @default.
• W2893603452 cites W1755350398 @default.
• W2893603452 cites W1893315106 @default.
• W2893603452 cites W1977543000 @default.
• W2893603452 cites W1993230388 @default.
• W2893603452 cites W1998008454 @default.
• W2893603452 cites W2020639647 @default.
• W2893603452 cites W2021059130 @default.
• W2893603452 cites W2021061189 @default.
• W2893603452 cites W2021205495 @default.
• W2893603452 cites W2040018188 @default.
• W2893603452 cites W2040036069 @default.
• W2893603452 cites W2040383487 @default.
• W2893603452 cites W2050083874 @default.
• W2893603452 cites W2069760101 @default.
• W2893603452 cites W2100822576 @default.
• W2893603452 cites W2108233057 @default.
• W2893603452 cites W2123001862 @default.
• W2893603452 cites W2147261346 @default.
• W2893603452 cites W2158840452 @default.
• W2893603452 cites W2392129939 @default.
• W2893603452 cites W2470546931 @default.
• W2893603452 cites W2555321629 @default.
• W2893603452 cites W2563473464 @default.
• W2893603452 cites W2606346746 @default.
• W2893603452 cites W2750918355 @default.
• W2893603452 cites W2765321549 @default.
• W2893603452 cites W2782325848 @default.
• W2893603452 doi "https://doi.org/10.1177/0883073818798090" @default.
• W2893603452 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30261790" @default.
• W2893603452 hasPublicationYear "2018" @default.
• W2893603452 type Work @default.
• W2893603452 sameAs 2893603452 @default.
• W2893603452 citedByCount "3" @default.
• W2893603452 countsByYear W28936034522019 @default.
• W2893603452 countsByYear W28936034522021 @default.
• W2893603452 crossrefType "journal-article" @default.
• W2893603452 hasAuthorship W2893603452A5021803974 @default.
• W2893603452 hasAuthorship W2893603452A5047907963 @default.
• W2893603452 hasAuthorship W2893603452A5065566020 @default.
• W2893603452 hasConcept C126322002 @default.
• W2893603452 hasConcept C142724271 @default.
• W2893603452 hasConcept C167135981 @default.
• W2893603452 hasConcept C187212893 @default.
• W2893603452 hasConcept C2776100374 @default.
• W2893603452 hasConcept C2776326100 @default.
• W2893603452 hasConcept C2777408962 @default.
• W2893603452 hasConcept C2777585455 @default.
• W2893603452 hasConcept C2779134260 @default.
• W2893603452 hasConcept C2911091166 @default.
• W2893603452 hasConcept C71924100 @default.
• W2893603452 hasConceptScore W2893603452C126322002 @default.
• W2893603452 hasConceptScore W2893603452C142724271 @default.
• W2893603452 hasConceptScore W2893603452C167135981 @default.
• W2893603452 hasConceptScore W2893603452C187212893 @default.
• W2893603452 hasConceptScore W2893603452C2776100374 @default.
• W2893603452 hasConceptScore W2893603452C2776326100 @default.
• W2893603452 hasConceptScore W2893603452C2777408962 @default.
• W2893603452 hasConceptScore W2893603452C2777585455 @default.
• W2893603452 hasConceptScore W2893603452C2779134260 @default.
• W2893603452 hasConceptScore W2893603452C2911091166 @default.
• W2893603452 hasConceptScore W2893603452C71924100 @default.
• W2893603452 hasLocation W28936034521 @default.
• W2893603452 hasLocation W28936034522 @default.
• W2893603452 hasOpenAccess W2893603452 @default.
• W2893603452 hasPrimaryLocation W28936034521 @default.
• W2893603452 hasRelatedWork W194249328 @default.
• W2893603452 hasRelatedWork W1975770744 @default.
• W2893603452 hasRelatedWork W2037347481 @default.
• W2893603452 hasRelatedWork W2320430234 @default.
• W2893603452 hasRelatedWork W2341865657 @default.
• W2893603452 hasRelatedWork W2521110479 @default.
• W2893603452 hasRelatedWork W2893603452 @default.
• W2893603452 hasRelatedWork W3128641054 @default.
• W2893603452 hasRelatedWork W3157443444 @default.
• W2893603452 hasRelatedWork W57254166 @default.
• W2893603452 isParatext "false" @default.
• W2893603452 isRetracted "false" @default.
• W2893603452 magId "2893603452" @default.
• W2893603452 workType "article" @default.