FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893613859> ?p ?o ?g. }

• W2893613859 endingPage "322" @default.
• W2893613859 startingPage "322" @default.
• W2893613859 abstract "322 Objectives Radiosynoviorthesis (a.k.a. radiosynovectomy) employing the theranostic isotope, Sn-117m (t½ 14d, γ 159 keV, 86%), is well suited to treat smaller arthritic joints since the therapeutic conversion electrons (~140 keV, 112%) have a range of about 300 µm. This allows for treatment of the synovium without affecting the surrounding tissues. Retention of the colloidal product in the synovial cavity is highly desirable. We describe the joint retention and biodistribution trial measurements of Sn-117m colloid injected into normal canine elbows. Methods Five normal purpose-bred hounds were injected with ~2.5 mCi of a homogeneous preparation of Sn-117m colloid (~6 μm diameter) in the intra-articular space of the left elbow. The animals were sacrificed after six weeks (3 half-lives) and the amount of radioactivity in the dissected tissues was measured. Urine, blood, feces and synovial fluid samples were taken periodically during the trial and analyzed for radioactive content. Results Average joint retention of the colloid was 99.1% of the administered dose at three-half-lives. When integrated over the study period the activity in blood, urine and feces was Conclusions These results demonstrate a high degree of retention of the Sn-117m homogeneous colloid delivered intra-articularly. Other than minimal transient leakages possibly due to synovial punctures the results are consistent with a gradual removal of the colloid through the lymphatic system. The high joint retention supports the use of Sn-117m colloid in treating arthritis." @default.
• W2893613859 created "2018-10-05" @default.
• W2893613859 creator A5000051859 @default.
• W2893613859 creator A5013288329 @default.
• W2893613859 creator A5023673341 @default.
• W2893613859 creator A5029949102 @default.
• W2893613859 creator A5042417763 @default.
• W2893613859 creator A5052481062 @default.
• W2893613859 creator A5066980850 @default.
• W2893613859 date "2016-05-01" @default.
• W2893613859 modified "2023-09-27" @default.
• W2893613859 title "Retention and biodistribution of Sn-117m colloid in intra-articular injections" @default.
• W2893613859 hasPublicationYear "2016" @default.
• W2893613859 type Work @default.
• W2893613859 sameAs 2893613859 @default.
• W2893613859 citedByCount "0" @default.
• W2893613859 crossrefType "journal-article" @default.
• W2893613859 hasAuthorship W2893613859A5000051859 @default.
• W2893613859 hasAuthorship W2893613859A5013288329 @default.
• W2893613859 hasAuthorship W2893613859A5023673341 @default.
• W2893613859 hasAuthorship W2893613859A5029949102 @default.
• W2893613859 hasAuthorship W2893613859A5042417763 @default.
• W2893613859 hasAuthorship W2893613859A5052481062 @default.
• W2893613859 hasAuthorship W2893613859A5066980850 @default.
• W2893613859 hasConcept C121332964 @default.
• W2893613859 hasConcept C126322002 @default.
• W2893613859 hasConcept C141071460 @default.
• W2893613859 hasConcept C142724271 @default.
• W2893613859 hasConcept C147789679 @default.
• W2893613859 hasConcept C185592680 @default.
• W2893613859 hasConcept C202751555 @default.
• W2893613859 hasConcept C204787440 @default.
• W2893613859 hasConcept C2775882047 @default.
• W2893613859 hasConcept C2776164576 @default.
• W2893613859 hasConcept C2776268809 @default.
• W2893613859 hasConcept C2777077863 @default.
• W2893613859 hasConcept C2777575956 @default.
• W2893613859 hasConcept C2777807558 @default.
• W2893613859 hasConcept C2779244835 @default.
• W2893613859 hasConcept C2780026642 @default.
• W2893613859 hasConcept C2780931953 @default.
• W2893613859 hasConcept C2781184374 @default.
• W2893613859 hasConcept C2989005 @default.
• W2893613859 hasConcept C2993559085 @default.
• W2893613859 hasConcept C522557706 @default.
• W2893613859 hasConcept C55493867 @default.
• W2893613859 hasConcept C59789625 @default.
• W2893613859 hasConcept C66882249 @default.
• W2893613859 hasConcept C71924100 @default.
• W2893613859 hasConcept C97355855 @default.
• W2893613859 hasConceptScore W2893613859C121332964 @default.
• W2893613859 hasConceptScore W2893613859C126322002 @default.
• W2893613859 hasConceptScore W2893613859C141071460 @default.
• W2893613859 hasConceptScore W2893613859C142724271 @default.
• W2893613859 hasConceptScore W2893613859C147789679 @default.
• W2893613859 hasConceptScore W2893613859C185592680 @default.
• W2893613859 hasConceptScore W2893613859C202751555 @default.
• W2893613859 hasConceptScore W2893613859C204787440 @default.
• W2893613859 hasConceptScore W2893613859C2775882047 @default.
• W2893613859 hasConceptScore W2893613859C2776164576 @default.
• W2893613859 hasConceptScore W2893613859C2776268809 @default.
• W2893613859 hasConceptScore W2893613859C2777077863 @default.
• W2893613859 hasConceptScore W2893613859C2777575956 @default.
• W2893613859 hasConceptScore W2893613859C2777807558 @default.
• W2893613859 hasConceptScore W2893613859C2779244835 @default.
• W2893613859 hasConceptScore W2893613859C2780026642 @default.
• W2893613859 hasConceptScore W2893613859C2780931953 @default.
• W2893613859 hasConceptScore W2893613859C2781184374 @default.
• W2893613859 hasConceptScore W2893613859C2989005 @default.
• W2893613859 hasConceptScore W2893613859C2993559085 @default.
• W2893613859 hasConceptScore W2893613859C522557706 @default.
• W2893613859 hasConceptScore W2893613859C55493867 @default.
• W2893613859 hasConceptScore W2893613859C59789625 @default.
• W2893613859 hasConceptScore W2893613859C66882249 @default.
• W2893613859 hasConceptScore W2893613859C71924100 @default.
• W2893613859 hasConceptScore W2893613859C97355855 @default.
• W2893613859 hasOpenAccess W2893613859 @default.
• W2893613859 hasRelatedWork W108043863 @default.
• W2893613859 hasRelatedWork W1915280205 @default.
• W2893613859 hasRelatedWork W2004763863 @default.
• W2893613859 hasRelatedWork W2043338591 @default.
• W2893613859 hasRelatedWork W2048350313 @default.
• W2893613859 hasRelatedWork W2048591647 @default.
• W2893613859 hasRelatedWork W2058045796 @default.
• W2893613859 hasRelatedWork W2072492587 @default.
• W2893613859 hasRelatedWork W2074027145 @default.
• W2893613859 hasRelatedWork W2309691057 @default.
• W2893613859 hasRelatedWork W2337333883 @default.
• W2893613859 hasRelatedWork W2350591343 @default.
• W2893613859 hasRelatedWork W2361179806 @default.
• W2893613859 hasRelatedWork W2377263799 @default.
• W2893613859 hasRelatedWork W2380256145 @default.
• W2893613859 hasRelatedWork W2402931711 @default.
• W2893613859 hasRelatedWork W2462238073 @default.
• W2893613859 hasRelatedWork W2955243294 @default.
• W2893613859 hasRelatedWork W3030247377 @default.
• W2893613859 hasRelatedWork W2473490102 @default.
• W2893613859 hasVolume "57" @default.

• next