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• W2893637560 abstract "How SIV progenitors evolved into deadly HIV-1 and HIV-2 following initial cross-species transmission still remains a mystery. Here, we used humanized mice as a human surrogate system to evaluate SIVsm evolution into HIV-2. Increased viral virulence to human CD4+ T cells and adaptive genetic changes were observed during serial passages." @default.
• W2893637560 created "2018-10-05" @default.
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• W2893637560 date "2018-09-26" @default.
• W2893637560 modified "2023-09-30" @default.
• W2893637560 title "SIV progenitor evolution toward HIV: A humanized mouse surrogate model for SIVsm adaptation toward HIV-2" @default.
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• W2893637560 doi "https://doi.org/10.1111/jmp.12380" @default.
• W2893637560 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6464631" @default.
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• W2893637560 hasPublicationYear "2018" @default.
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