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- W2893657767 abstract "The review is focused on clinical significance of the left ventricle hypertrophy (LVH) — presentation of heart lesion as a target organ for systemic hypertension (SH). Various LVH development mechanisms are presented, and special attention is paid to sympathic nervous system and β-adrenoreceptors in pathogenesis. Fundamental methods of diagnostics are described for LVH, in comparison. The pathology is classified from the perspective of recent guidelines on echocardiographic diagnostics. Epidemiology provided. Taken current evidence, the prognostic role of LVH is described as a factor increasing the risk of fatal and non-fatal cardiovascular, cerebrovascular and renal complications in SH patients. Trials data presented that points on LVH regression with highly selective β 1 -blocker bisoprolol treatment. Pathophysiology of LVH regression is discussed for β 1 -blocker treatment." @default.
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- W2893657767 date "2018-09-24" @default.
- W2893657767 modified "2023-10-05" @default.
- W2893657767 title "High sympathetic tone in development of the left ventricle hypertrophy and beta-blockers for regression" @default.
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- W2893657767 doi "https://doi.org/10.15829/1560-4071-2018-9-77-88" @default.
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