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• W2893678166 abstract "This work establishes amphiphilic polymethacrylates as new antimicrobial candidates that can be synthesized through a combination of controlled free radical polymerization and sequential postpolymerization modification protocols. When conjugated with a polyethylene glycol segment, the block copolymers exhibit a balanced performance between high antibacterial activity and high hemocompatibility. Figure S1. 1H NMR spectra of PGMA homopolymer in CDCl3. Signals arising from residual solvent and tetramethylsilane are shown with asterisk. Figure S2. 1H NMR spectra of PEG-b-PGMA block copolymer in CDCl3. Signals arising from residual solvent and tetramethylsilane are shown with asterisk. Figure S3. 1H NMR spectra of P4 block copolymer in CDCl3. Signals arising from residual solvent and tetramethylsilane are shown with asterisk. Figure S4. CLSM images of E. coli cells after 4h of incubation in the presence of (a) control solution, (b) PC5A homopolymer, and (c) PEG-b-PC5A block copolymer, respectively. All CLSM images here 8 are merged images of the green (SYTO, indicates live cells) and red (propidium iodide, indicates dead cells) channels. The bacteria suspension without polymers was used as control. Figure S5. Hemolysis testing, where percent hemolysis of RBCs as a function of relevant antimicrobial concentrations is shown for all synthesized polymers. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
• W2893678166 created "2018-10-05" @default.
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• W2893678166 date "2018-09-21" @default.
• W2893678166 modified "2023-10-14" @default.
• W2893678166 title "Balancing antimicrobial performance with hemocompatibility in amphiphilic homopolymers" @default.
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• W2893678166 doi "https://doi.org/10.1002/pola.29213" @default.
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