FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893683238> ?p ?o ?g. }

• W2893683238 endingPage "846" @default.
• W2893683238 startingPage "831" @default.
• W2893683238 abstract "Summary Centrins belong to a family of proteins containing calcium‐binding EF‐hand motifs that perform well‐established roles in centrosome and spindle pole body (SPB) duplication. Yeast encodes a single Centrin protein (Cdc31) that binds components in the SPB. However, further studies revealed a role for Centrins in mRNA export, and interactions with contractile filaments and photoreceptors. In addition, human Centrin‐2 can bind the DNA‐lesion recognition factor XPC, and improve the efficiency of nucleotide excision repair. Similarly, we reported that yeast Cdc31 binds Rad4, a functional counterpart of the XPC DNA repair protein. We also found that Cdc31 is involved in the ubiquitin/proteasome system, and mutations interfere with intracellular protein turnover. In this report, we describe new findings that indicate a role for Cdc31 in the energy metabolism pathway. Cdc31 and cdc31 mutant proteins showed distinct interactions with proteins in energy metabolism, and mutants showed sensitivity to oxidative stress and poor growth on non‐fermentable carbon. Significant alteration in mitochondrial morphology was also detected. Although it is unclear how Cdc31 contributes to so many unrelated mechanisms, we propose that by controlling SPB duplication Centrin proteins might link the cellular responses to DNA damage, oxidative load and proteotoxic stresses to growth control." @default.
• W2893683238 created "2018-10-05" @default.
• W2893683238 creator A5014068004 @default.
• W2893683238 creator A5037989560 @default.
• W2893683238 creator A5061445095 @default.
• W2893683238 creator A5082286933 @default.
• W2893683238 date "2018-10-28" @default.
• W2893683238 modified "2023-10-14" @default.
• W2893683238 title "A role for<i>Saccharomyces cerevisiae</i>Centrin (Cdc31) in mitochondrial function and biogenesis" @default.
• W2893683238 cites W1964486891 @default.
• W2893683238 cites W1969270834 @default.
• W2893683238 cites W1969971056 @default.
• W2893683238 cites W1976645698 @default.
• W2893683238 cites W1977643725 @default.
• W2893683238 cites W1979540290 @default.
• W2893683238 cites W1982176828 @default.
• W2893683238 cites W1983319101 @default.
• W2893683238 cites W1985955125 @default.
• W2893683238 cites W1986225421 @default.
• W2893683238 cites W1986455196 @default.
• W2893683238 cites W1993330845 @default.
• W2893683238 cites W1995679594 @default.
• W2893683238 cites W2006422228 @default.
• W2893683238 cites W2007773837 @default.
• W2893683238 cites W2008541773 @default.
• W2893683238 cites W2009018280 @default.
• W2893683238 cites W2012603518 @default.
• W2893683238 cites W2020484714 @default.
• W2893683238 cites W2022001968 @default.
• W2893683238 cites W2023446808 @default.
• W2893683238 cites W2028468004 @default.
• W2893683238 cites W2030837975 @default.
• W2893683238 cites W2033062319 @default.
• W2893683238 cites W2051743464 @default.
• W2893683238 cites W2057305872 @default.
• W2893683238 cites W2058600022 @default.
• W2893683238 cites W2059754953 @default.
• W2893683238 cites W2064448884 @default.
• W2893683238 cites W2070461712 @default.
• W2893683238 cites W2071628857 @default.
• W2893683238 cites W2072383950 @default.
• W2893683238 cites W2074314807 @default.
• W2893683238 cites W2074673397 @default.
• W2893683238 cites W2074967874 @default.
• W2893683238 cites W2077795009 @default.
• W2893683238 cites W2084389717 @default.
• W2893683238 cites W2085261864 @default.
• W2893683238 cites W2090945233 @default.
• W2893683238 cites W2093048008 @default.
• W2893683238 cites W2099249575 @default.
• W2893683238 cites W2105162444 @default.
• W2893683238 cites W2113085291 @default.
• W2893683238 cites W2114873132 @default.
• W2893683238 cites W2116730865 @default.
• W2893683238 cites W2118055121 @default.
• W2893683238 cites W2118327122 @default.
• W2893683238 cites W2121132785 @default.
• W2893683238 cites W2123456626 @default.
• W2893683238 cites W2125295202 @default.
• W2893683238 cites W2133201628 @default.
• W2893683238 cites W2134084617 @default.
• W2893683238 cites W2136937485 @default.
• W2893683238 cites W2146343693 @default.
• W2893683238 cites W2149060516 @default.
• W2893683238 cites W2149327250 @default.
• W2893683238 cites W2157247790 @default.
• W2893683238 cites W2162342949 @default.
• W2893683238 cites W2163813747 @default.
• W2893683238 cites W2165822900 @default.
• W2893683238 cites W2166998501 @default.
• W2893683238 cites W2168234700 @default.
• W2893683238 cites W2184627161 @default.
• W2893683238 cites W2227191494 @default.
• W2893683238 cites W2279531754 @default.
• W2893683238 doi "https://doi.org/10.1111/mmi.14128" @default.
• W2893683238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30251372" @default.
• W2893683238 hasPublicationYear "2018" @default.
• W2893683238 type Work @default.
• W2893683238 sameAs 2893683238 @default.
• W2893683238 citedByCount "3" @default.
• W2893683238 countsByYear W28936832382021 @default.
• W2893683238 countsByYear W28936832382023 @default.
• W2893683238 crossrefType "journal-article" @default.
• W2893683238 hasAuthorship W2893683238A5014068004 @default.
• W2893683238 hasAuthorship W2893683238A5037989560 @default.
• W2893683238 hasAuthorship W2893683238A5061445095 @default.
• W2893683238 hasAuthorship W2893683238A5082286933 @default.
• W2893683238 hasBestOaLocation W28936832381 @default.
• W2893683238 hasConcept C104317684 @default.
• W2893683238 hasConcept C134935766 @default.
• W2893683238 hasConcept C143065580 @default.
• W2893683238 hasConcept C143425029 @default.
• W2893683238 hasConcept C1491633281 @default.
• W2893683238 hasConcept C2777576037 @default.
• W2893683238 hasConcept C28859421 @default.
• W2893683238 hasConcept C47432576 @default.
• W2893683238 hasConcept C54355233 @default.
• W2893683238 hasConcept C552990157 @default.

• next