Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893687574> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2893687574 endingPage "14" @default.
- W2893687574 startingPage "9" @default.
- W2893687574 abstract "Excess urinary orotic acid excretion occurs in patients with some inborn errors of metabolic pathways such as pyrimidine synthesis and urea cycle. Thus, rapid diagnosis of orotic aciduria has a vital importance for patients. In this paper, a novel method for determination of orotic acid in urine samples by ion chromatography with suppressed conductivity detection was investigated. The separation of orotic acid from urine matrix was accomplished by using an anion exchange column with optimized isocratic eluent program which utilized 50 mM NaOH. The other chromatographic conditions were as follows: the suppressor current was 31 mA; the flow rate of mobile phase was 0.25 mL min−1; the column temperature was 30 °C; sample loop volume was 10 μL. Under optimized conditions, the limit of detection was 0.2 μmol L‾1. Dramatically elevated orotic acid concentration was observed on pathological urine samples comparing to healthy urines, as expected. There are a good many advantages of the proposed method, but using an environmentally friendly reagent free system, no organic solvent employment and its quick nature, and being a sensitive and reliable method are the most obvious ones. The proposed method, therefore, may be utilized as an alternative technique for clinical laboratories." @default.
- W2893687574 created "2018-10-05" @default.
- W2893687574 creator A5004692938 @default.
- W2893687574 creator A5031446266 @default.
- W2893687574 creator A5057361557 @default.
- W2893687574 creator A5090753320 @default.
- W2893687574 date "2018-12-01" @default.
- W2893687574 modified "2023-10-03" @default.
- W2893687574 title "Ion chromatographic method for the determination of orotic acid in urine" @default.
- W2893687574 cites W1507540753 @default.
- W2893687574 cites W1967985070 @default.
- W2893687574 cites W1976732058 @default.
- W2893687574 cites W1994010573 @default.
- W2893687574 cites W1997338257 @default.
- W2893687574 cites W2005193715 @default.
- W2893687574 cites W2013204547 @default.
- W2893687574 cites W2021017345 @default.
- W2893687574 cites W2028344116 @default.
- W2893687574 cites W2038303182 @default.
- W2893687574 cites W2048983884 @default.
- W2893687574 cites W2073170453 @default.
- W2893687574 cites W2073822207 @default.
- W2893687574 cites W2076139058 @default.
- W2893687574 cites W2092724327 @default.
- W2893687574 cites W2098523127 @default.
- W2893687574 cites W2132959499 @default.
- W2893687574 cites W2148839738 @default.
- W2893687574 cites W380427189 @default.
- W2893687574 doi "https://doi.org/10.1016/j.ab.2018.09.016" @default.
- W2893687574 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30267708" @default.
- W2893687574 hasPublicationYear "2018" @default.
- W2893687574 type Work @default.
- W2893687574 sameAs 2893687574 @default.
- W2893687574 citedByCount "3" @default.
- W2893687574 countsByYear W28936875742020 @default.
- W2893687574 crossrefType "journal-article" @default.
- W2893687574 hasAuthorship W2893687574A5004692938 @default.
- W2893687574 hasAuthorship W2893687574A5031446266 @default.
- W2893687574 hasAuthorship W2893687574A5057361557 @default.
- W2893687574 hasAuthorship W2893687574A5090753320 @default.
- W2893687574 hasConcept C119128265 @default.
- W2893687574 hasConcept C147789679 @default.
- W2893687574 hasConcept C185592680 @default.
- W2893687574 hasConcept C206967267 @default.
- W2893687574 hasConcept C2775851010 @default.
- W2893687574 hasConcept C2780026642 @default.
- W2893687574 hasConcept C2780365088 @default.
- W2893687574 hasConcept C2780471494 @default.
- W2893687574 hasConcept C40875361 @default.
- W2893687574 hasConcept C43617362 @default.
- W2893687574 hasConcept C51724486 @default.
- W2893687574 hasConcept C55493867 @default.
- W2893687574 hasConceptScore W2893687574C119128265 @default.
- W2893687574 hasConceptScore W2893687574C147789679 @default.
- W2893687574 hasConceptScore W2893687574C185592680 @default.
- W2893687574 hasConceptScore W2893687574C206967267 @default.
- W2893687574 hasConceptScore W2893687574C2775851010 @default.
- W2893687574 hasConceptScore W2893687574C2780026642 @default.
- W2893687574 hasConceptScore W2893687574C2780365088 @default.
- W2893687574 hasConceptScore W2893687574C2780471494 @default.
- W2893687574 hasConceptScore W2893687574C40875361 @default.
- W2893687574 hasConceptScore W2893687574C43617362 @default.
- W2893687574 hasConceptScore W2893687574C51724486 @default.
- W2893687574 hasConceptScore W2893687574C55493867 @default.
- W2893687574 hasFunder F4320324489 @default.
- W2893687574 hasLocation W28936875741 @default.
- W2893687574 hasLocation W28936875742 @default.
- W2893687574 hasOpenAccess W2893687574 @default.
- W2893687574 hasPrimaryLocation W28936875741 @default.
- W2893687574 hasRelatedWork W1914889820 @default.
- W2893687574 hasRelatedWork W1983558225 @default.
- W2893687574 hasRelatedWork W2000779496 @default.
- W2893687574 hasRelatedWork W2017325659 @default.
- W2893687574 hasRelatedWork W2023342487 @default.
- W2893687574 hasRelatedWork W2027632068 @default.
- W2893687574 hasRelatedWork W2133307692 @default.
- W2893687574 hasRelatedWork W2375914055 @default.
- W2893687574 hasRelatedWork W2429445208 @default.
- W2893687574 hasRelatedWork W4283454125 @default.
- W2893687574 hasVolume "563" @default.
- W2893687574 isParatext "false" @default.
- W2893687574 isRetracted "false" @default.
- W2893687574 magId "2893687574" @default.
- W2893687574 workType "article" @default.