FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893690017> ?p ?o ?g. }

• W2893690017 endingPage "1271" @default.
• W2893690017 startingPage "1263" @default.
• W2893690017 abstract "Cyclin dependent kinase inhibitor 2A gene (CDKN2A) germline mutations have recently been associated with poor survival in patients with melanoma. Despite the high mutation rate in our cohort (up to 10% in patients with apparently sporadic melanoma), information on the impact of CDKN2A on survival in this cohort is lacking.To investigate whether poor survival associated with CDKN2A germline mutations was confirmed in a high mutation-prevalence cohort of Italian patients with melanoma undergoing a mutation-based follow-up.A total of 1239 patients with cutaneous melanoma were tested for CDKN2A mutational status and then assigned to a follow-up scheme according not only to family history but also to CDKN2A mutational status, as follow-up intervals were more frequent for CDKN2A germline mutation-positive (MUT+) patients. From this cohort, we selected 106 MUT+ patients (with familial melanoma or apparently sporadic melanoma) and 199 CDKN2A germline mutation-negative (MUT-) patients with sporadic melanoma who were matched by age and sex and had a similar tumor stage distribution.We found no difference in overall survival (hazard ratio, 0.85; 95% confidence interval, 0.48-1.52; P = .592,) or melanoma-specific survival (hazard ratio, 0.86; 95% confidence interval, 0.38-1.95; P = .718,) between MUT+ and MUT- patients. MUT+ patients were more likely to develop multiple melanomas and to undergo surgical excision of dysplastic nevi than were MUT- patients.Retrospective study.CDKN2A mutations were not associated with survival in our cohort." @default.
• W2893690017 created "2018-10-05" @default.
• W2893690017 creator A5004158910 @default.
• W2893690017 creator A5007240762 @default.
• W2893690017 creator A5025473720 @default.
• W2893690017 creator A5036052073 @default.
• W2893690017 creator A5053034134 @default.
• W2893690017 creator A5055146321 @default.
• W2893690017 creator A5057849200 @default.
• W2893690017 creator A5060922137 @default.
• W2893690017 creator A5071929183 @default.
• W2893690017 creator A5072894277 @default.
• W2893690017 creator A5089884124 @default.
• W2893690017 date "2019-05-01" @default.
• W2893690017 modified "2023-10-14" @default.
• W2893690017 title "CDKN2A germline mutations are not associated with poor survival in an Italian cohort of melanoma patients" @default.
• W2893690017 cites W1520625029 @default.
• W2893690017 cites W1968043000 @default.
• W2893690017 cites W1983554886 @default.
• W2893690017 cites W1991825197 @default.
• W2893690017 cites W2004984342 @default.
• W2893690017 cites W2008616879 @default.
• W2893690017 cites W2014776263 @default.
• W2893690017 cites W2022779163 @default.
• W2893690017 cites W2026376689 @default.
• W2893690017 cites W2028621040 @default.
• W2893690017 cites W2048001425 @default.
• W2893690017 cites W2064040729 @default.
• W2893690017 cites W2087791044 @default.
• W2893690017 cites W2088225476 @default.
• W2893690017 cites W2097096041 @default.
• W2893690017 cites W2106621675 @default.
• W2893690017 cites W2113496553 @default.
• W2893690017 cites W2118863192 @default.
• W2893690017 cites W2128360321 @default.
• W2893690017 cites W2131785547 @default.
• W2893690017 cites W2141317943 @default.
• W2893690017 cites W2167028317 @default.
• W2893690017 cites W2238534137 @default.
• W2893690017 cites W2410675151 @default.
• W2893690017 cites W2505751991 @default.
• W2893690017 cites W2579106043 @default.
• W2893690017 cites W2594856347 @default.
• W2893690017 cites W2749383529 @default.
• W2893690017 cites W4211020617 @default.
• W2893690017 cites W4293166735 @default.
• W2893690017 doi "https://doi.org/10.1016/j.jaad.2018.07.060" @default.
• W2893690017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30274933" @default.
• W2893690017 hasPublicationYear "2019" @default.
• W2893690017 type Work @default.
• W2893690017 sameAs 2893690017 @default.
• W2893690017 citedByCount "12" @default.
• W2893690017 countsByYear W28936900172020 @default.
• W2893690017 countsByYear W28936900172021 @default.
• W2893690017 countsByYear W28936900172022 @default.
• W2893690017 countsByYear W28936900172023 @default.
• W2893690017 crossrefType "journal-article" @default.
• W2893690017 hasAuthorship W2893690017A5004158910 @default.
• W2893690017 hasAuthorship W2893690017A5007240762 @default.
• W2893690017 hasAuthorship W2893690017A5025473720 @default.
• W2893690017 hasAuthorship W2893690017A5036052073 @default.
• W2893690017 hasAuthorship W2893690017A5053034134 @default.
• W2893690017 hasAuthorship W2893690017A5055146321 @default.
• W2893690017 hasAuthorship W2893690017A5057849200 @default.
• W2893690017 hasAuthorship W2893690017A5060922137 @default.
• W2893690017 hasAuthorship W2893690017A5071929183 @default.
• W2893690017 hasAuthorship W2893690017A5072894277 @default.
• W2893690017 hasAuthorship W2893690017A5089884124 @default.
• W2893690017 hasConcept C104317684 @default.
• W2893690017 hasConcept C109825262 @default.
• W2893690017 hasConcept C121608353 @default.
• W2893690017 hasConcept C126322002 @default.
• W2893690017 hasConcept C13514818 @default.
• W2893690017 hasConcept C143998085 @default.
• W2893690017 hasConcept C167135981 @default.
• W2893690017 hasConcept C207103383 @default.
• W2893690017 hasConcept C2777658100 @default.
• W2893690017 hasConcept C2780265364 @default.
• W2893690017 hasConcept C44249647 @default.
• W2893690017 hasConcept C501734568 @default.
• W2893690017 hasConcept C502942594 @default.
• W2893690017 hasConcept C54355233 @default.
• W2893690017 hasConcept C71924100 @default.
• W2893690017 hasConcept C72563966 @default.
• W2893690017 hasConcept C86803240 @default.
• W2893690017 hasConceptScore W2893690017C104317684 @default.
• W2893690017 hasConceptScore W2893690017C109825262 @default.
• W2893690017 hasConceptScore W2893690017C121608353 @default.
• W2893690017 hasConceptScore W2893690017C126322002 @default.
• W2893690017 hasConceptScore W2893690017C13514818 @default.
• W2893690017 hasConceptScore W2893690017C143998085 @default.
• W2893690017 hasConceptScore W2893690017C167135981 @default.
• W2893690017 hasConceptScore W2893690017C207103383 @default.
• W2893690017 hasConceptScore W2893690017C2777658100 @default.
• W2893690017 hasConceptScore W2893690017C2780265364 @default.
• W2893690017 hasConceptScore W2893690017C44249647 @default.
• W2893690017 hasConceptScore W2893690017C501734568 @default.
• W2893690017 hasConceptScore W2893690017C502942594 @default.

• next