Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893702172> ?p ?o ?g. }
- W2893702172 endingPage "11231" @default.
- W2893702172 startingPage "11226" @default.
- W2893702172 abstract "Significance Accurate gene expression is essential in all organisms. During protein synthesis, transfer RNAs (tRNAs) decode the genetic information contained in messenger RNA (mRNA) on the ribosome into amino acids using a defined 3-nt code. A fundamental question in biology is how the ribosome maintains this 3-nt code, or mRNA frame, during the dynamic processes that move the mRNA-tRNA pairs through the different tRNA-binding sites. We solved structures of a frameshift-prone tRNA bound to the bacterial ribosome after mRNA decoding. We find that the tRNA undergoes conformational rearrangements in the peptidyl (P) and exit (E) sites that cause the ribosome to lose its grip on the mRNA and allow the tRNA to shift into a new reading frame." @default.
- W2893702172 created "2018-10-05" @default.
- W2893702172 creator A5011433226 @default.
- W2893702172 creator A5032765426 @default.
- W2893702172 creator A5034397418 @default.
- W2893702172 creator A5059990450 @default.
- W2893702172 creator A5075481978 @default.
- W2893702172 creator A5079022989 @default.
- W2893702172 date "2018-09-27" @default.
- W2893702172 modified "2023-10-16" @default.
- W2893702172 title "Mechanism of tRNA-mediated +1 ribosomal frameshifting" @default.
- W2893702172 cites W1579537489 @default.
- W2893702172 cites W179740174 @default.
- W2893702172 cites W1855841377 @default.
- W2893702172 cites W1964787147 @default.
- W2893702172 cites W1965939160 @default.
- W2893702172 cites W1970969100 @default.
- W2893702172 cites W1974067623 @default.
- W2893702172 cites W1976678081 @default.
- W2893702172 cites W1985441949 @default.
- W2893702172 cites W1999249940 @default.
- W2893702172 cites W2000701969 @default.
- W2893702172 cites W2001838510 @default.
- W2893702172 cites W2007146973 @default.
- W2893702172 cites W2008815053 @default.
- W2893702172 cites W2009185547 @default.
- W2893702172 cites W2013411884 @default.
- W2893702172 cites W2021008054 @default.
- W2893702172 cites W2022754910 @default.
- W2893702172 cites W2029551024 @default.
- W2893702172 cites W2030519638 @default.
- W2893702172 cites W2032024543 @default.
- W2893702172 cites W2032521665 @default.
- W2893702172 cites W2036284784 @default.
- W2893702172 cites W2039279732 @default.
- W2893702172 cites W2041730140 @default.
- W2893702172 cites W2041766079 @default.
- W2893702172 cites W2044948205 @default.
- W2893702172 cites W2053765353 @default.
- W2893702172 cites W2057014596 @default.
- W2893702172 cites W2062660287 @default.
- W2893702172 cites W2062841623 @default.
- W2893702172 cites W2073504319 @default.
- W2893702172 cites W2082102231 @default.
- W2893702172 cites W2085123777 @default.
- W2893702172 cites W2087217881 @default.
- W2893702172 cites W2092203148 @default.
- W2893702172 cites W2093041571 @default.
- W2893702172 cites W2103429630 @default.
- W2893702172 cites W2115457325 @default.
- W2893702172 cites W2121748641 @default.
- W2893702172 cites W2124026197 @default.
- W2893702172 cites W2126780661 @default.
- W2893702172 cites W2127285213 @default.
- W2893702172 cites W2132367978 @default.
- W2893702172 cites W2134410571 @default.
- W2893702172 cites W2142152307 @default.
- W2893702172 cites W2146240180 @default.
- W2893702172 cites W2146912125 @default.
- W2893702172 cites W2158984519 @default.
- W2893702172 cites W2170708210 @default.
- W2893702172 cites W2180229411 @default.
- W2893702172 cites W2294416498 @default.
- W2893702172 cites W2417125774 @default.
- W2893702172 cites W2493667413 @default.
- W2893702172 cites W2786916506 @default.
- W2893702172 cites W3164064520 @default.
- W2893702172 cites W415135089 @default.
- W2893702172 cites W4233309275 @default.
- W2893702172 cites W4248872320 @default.
- W2893702172 doi "https://doi.org/10.1073/pnas.1809319115" @default.
- W2893702172 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6217423" @default.
- W2893702172 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30262649" @default.
- W2893702172 hasPublicationYear "2018" @default.
- W2893702172 type Work @default.
- W2893702172 sameAs 2893702172 @default.
- W2893702172 citedByCount "37" @default.
- W2893702172 countsByYear W28937021722018 @default.
- W2893702172 countsByYear W28937021722019 @default.
- W2893702172 countsByYear W28937021722020 @default.
- W2893702172 countsByYear W28937021722021 @default.
- W2893702172 countsByYear W28937021722022 @default.
- W2893702172 countsByYear W28937021722023 @default.
- W2893702172 crossrefType "journal-article" @default.
- W2893702172 hasAuthorship W2893702172A5011433226 @default.
- W2893702172 hasAuthorship W2893702172A5032765426 @default.
- W2893702172 hasAuthorship W2893702172A5034397418 @default.
- W2893702172 hasAuthorship W2893702172A5059990450 @default.
- W2893702172 hasAuthorship W2893702172A5075481978 @default.
- W2893702172 hasAuthorship W2893702172A5079022989 @default.
- W2893702172 hasBestOaLocation W28937021721 @default.
- W2893702172 hasConcept C104317684 @default.
- W2893702172 hasConcept C105580179 @default.
- W2893702172 hasConcept C106774688 @default.
- W2893702172 hasConcept C10853874 @default.
- W2893702172 hasConcept C114847915 @default.
- W2893702172 hasConcept C149364088 @default.
- W2893702172 hasConcept C153957851 @default.