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• W2893751393 abstract "The direct to consumer (DTC)2 genetic testing market was initiated in 2007 with the introduction of 23andMe. Since then, there has been marked expansion and, at the same time, considerable efforts to scrutinize the potential benefits and harms of such testing (1). The various tests are heterogeneous, with output ranging from medical data to ancestry to lifestyle. Along the way, fitness-centered DTC genetic tests have cropped up, encouraging consumers to pay, as we will briefly describe here, high costs for what we feel to be low value information. These tests promise insights about nutrition, healthy aging, weight loss, and athletic aptitude (even for specific sports). They market faux scientific authority, engendering confusion and the potential for harm, no less diminishing consumer confidence in validated, actionable, genetic tests.The genetic testing market is currently divided into 2 main categories with a couple of exceptions that operate in both arenas. Clinical tests require that a physician order each test, are subject to regulatory oversight, and are aimed at diagnosing or screening for mutations related to specific medical conditions. In contrast, DTC tests are purchased without any need for physician involvement. Current surveys identify approximately 40 companies offering DTC fitness genetic tests (2) and several companies that serve as a marketplace for purchasing a variety of such tests interpreted by third parties. Although registries exist to provide some assistance for medical genetics professionals to choose between the approximately 75000 clinical genetic tests available (3), there is no such resource for consumers. DTC genetic test prices range from under $30 to well over $1000. The less expensive tests are generally for individual single nucleotide variants, and marketing by some DTC companies drives sales of multiple tests per customer. The DTC genetic testing market is estimated to total about $100 million in 2017, with …" @default.
• W2893751393 created "2018-10-05" @default.
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• W2893751393 date "2019-01-01" @default.
• W2893751393 modified "2023-09-25" @default.
• W2893751393 title "Direct to Consumer Fitness DNA Testing" @default.
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• W2893751393 doi "https://doi.org/10.1373/clinchem.2018.287326" @default.
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