FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893755204> ?p ?o ?g. }

• W2893755204 endingPage "56" @default.
• W2893755204 startingPage "52" @default.
• W2893755204 abstract "Toxoplasmosis is an infectious disease caused by the intracellular parasite Toxoplasma gondii. Although almost 1/3 of the world’s population are seropositive, there is no effective vaccine against toxoplasmosis. Therefore, the development of an effective vaccine for control of toxoplasmosis is one of major concerns in parasitology. The aim of this study was to evaluate the efficacy of nano-liposomal excretory-secretory antigens (NLESA) in BALB/c mice. Excretory-secretory antigens (ESA) was obtained from tachyzoites, encapsulated in the liposome and studied by scanning electron microscope. BALB/c mice were immunized with NLESA and ESA, sterile phosphate-buffered saline (PBS). Immunization was performed three times at 14-day intervals and challenged with 1 × 104 tachyzoites of T. gondii RH strain four weeks later. The parasite load of mice blood, brain and spleen tissues were determined using quantitative PCR targeted at the repeated element (RE) gene. The immunization with NLESA and ESA induced a significant increase of anti-Toxoplasma IgG antibody compared with PBS group (P < 0.05). After challenge with tachyzoites, qPCR analyses showed significant reduction of parasite load in NLESA and ESA immunized mice compared with control group (P < 0.05). Also, NLESAs were more effective than ESAs and showed significantly reduced parasite load in blood (P = 0.001) and brain tissue (P = 0.01). The vaccination with NLESA showed more promising results comparing to ESA. Further studies are recommended in order to achieve effectiveness of the vaccine against T. gondii." @default.
• W2893755204 created "2018-10-05" @default.
• W2893755204 creator A5007642514 @default.
• W2893755204 creator A5011598532 @default.
• W2893755204 creator A5023083016 @default.
• W2893755204 creator A5025673778 @default.
• W2893755204 creator A5043708378 @default.
• W2893755204 creator A5050708589 @default.
• W2893755204 creator A5058470494 @default.
• W2893755204 creator A5073158218 @default.
• W2893755204 creator A5083088952 @default.
• W2893755204 creator A5088143950 @default.
• W2893755204 date "2018-08-01" @default.
• W2893755204 modified "2023-09-27" @default.
• W2893755204 title "Quantification of Toxoplasma gondii in the tissues of BALB/c mice after immunization with nanoliposomal excretory-secretory antigens using Real-Time PCR" @default.
• W2893755204 cites W1576684487 @default.
• W2893755204 cites W1775749144 @default.
• W2893755204 cites W1800833779 @default.
• W2893755204 cites W1861880998 @default.
• W2893755204 cites W1958713593 @default.
• W2893755204 cites W1968151012 @default.
• W2893755204 cites W1980461918 @default.
• W2893755204 cites W1985738307 @default.
• W2893755204 cites W1989474978 @default.
• W2893755204 cites W1990722146 @default.
• W2893755204 cites W2021917303 @default.
• W2893755204 cites W2024954594 @default.
• W2893755204 cites W2026705342 @default.
• W2893755204 cites W2032252611 @default.
• W2893755204 cites W2055922898 @default.
• W2893755204 cites W2071857583 @default.
• W2893755204 cites W2071940916 @default.
• W2893755204 cites W2078386684 @default.
• W2893755204 cites W2082870547 @default.
• W2893755204 cites W2096873907 @default.
• W2893755204 cites W2110443462 @default.
• W2893755204 cites W2118166742 @default.
• W2893755204 cites W2119703555 @default.
• W2893755204 cites W2142788740 @default.
• W2893755204 cites W2166410180 @default.
• W2893755204 cites W2321217361 @default.
• W2893755204 cites W2464695177 @default.
• W2893755204 cites W2552098157 @default.
• W2893755204 cites W2557947461 @default.
• W2893755204 cites W2594077466 @default.
• W2893755204 doi "https://doi.org/10.1016/j.cimid.2018.09.012" @default.
• W2893755204 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30290888" @default.
• W2893755204 hasPublicationYear "2018" @default.
• W2893755204 type Work @default.
• W2893755204 sameAs 2893755204 @default.
• W2893755204 citedByCount "6" @default.
• W2893755204 countsByYear W28937552042020 @default.
• W2893755204 countsByYear W28937552042021 @default.
• W2893755204 countsByYear W28937552042023 @default.
• W2893755204 crossrefType "journal-article" @default.
• W2893755204 hasAuthorship W2893755204A5007642514 @default.
• W2893755204 hasAuthorship W2893755204A5011598532 @default.
• W2893755204 hasAuthorship W2893755204A5023083016 @default.
• W2893755204 hasAuthorship W2893755204A5025673778 @default.
• W2893755204 hasAuthorship W2893755204A5043708378 @default.
• W2893755204 hasAuthorship W2893755204A5050708589 @default.
• W2893755204 hasAuthorship W2893755204A5058470494 @default.
• W2893755204 hasAuthorship W2893755204A5073158218 @default.
• W2893755204 hasAuthorship W2893755204A5083088952 @default.
• W2893755204 hasAuthorship W2893755204A5088143950 @default.
• W2893755204 hasConcept C147483822 @default.
• W2893755204 hasConcept C159047783 @default.
• W2893755204 hasConcept C159654299 @default.
• W2893755204 hasConcept C190612196 @default.
• W2893755204 hasConcept C203014093 @default.
• W2893755204 hasConcept C22070199 @default.
• W2893755204 hasConcept C2775993617 @default.
• W2893755204 hasConcept C2776529007 @default.
• W2893755204 hasConcept C2778062946 @default.
• W2893755204 hasConcept C2778128430 @default.
• W2893755204 hasConcept C2780801004 @default.
• W2893755204 hasConcept C2908647359 @default.
• W2893755204 hasConcept C71924100 @default.
• W2893755204 hasConcept C86803240 @default.
• W2893755204 hasConcept C8891405 @default.
• W2893755204 hasConcept C89423630 @default.
• W2893755204 hasConcept C90856448 @default.
• W2893755204 hasConcept C99454951 @default.
• W2893755204 hasConceptScore W2893755204C147483822 @default.
• W2893755204 hasConceptScore W2893755204C159047783 @default.
• W2893755204 hasConceptScore W2893755204C159654299 @default.
• W2893755204 hasConceptScore W2893755204C190612196 @default.
• W2893755204 hasConceptScore W2893755204C203014093 @default.
• W2893755204 hasConceptScore W2893755204C22070199 @default.
• W2893755204 hasConceptScore W2893755204C2775993617 @default.
• W2893755204 hasConceptScore W2893755204C2776529007 @default.
• W2893755204 hasConceptScore W2893755204C2778062946 @default.
• W2893755204 hasConceptScore W2893755204C2778128430 @default.
• W2893755204 hasConceptScore W2893755204C2780801004 @default.
• W2893755204 hasConceptScore W2893755204C2908647359 @default.
• W2893755204 hasConceptScore W2893755204C71924100 @default.
• W2893755204 hasConceptScore W2893755204C86803240 @default.
• W2893755204 hasConceptScore W2893755204C8891405 @default.

• next