Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893763469> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2893763469 abstract "Background: In this research, MIL-53(Fe) was magnetized and the performance of the magnetized material as a drug delivery system for doxycycline was studied. Objectives: The experiments were designed to load the magnetic delivery compounds with different amount of the drug. Methods: The in vitro release rate of doxycycline from magnetic MIL-53(Fe) with different drug content into saline buffered fluid (SBF, pH=7.4) and phosphate buffered saline (PBS, pH=3) was then studied. Results: The results showed that the releasing process of the drug in PBS media achieved the equilibration within 48h with 98% of releasing efficiency, while the releasing process in SBF media (pH=7.4) was slower and the equilibrium was established within 264 h with the releasing efficiency of 95%. The amount of the released doxycycline from the samples with different drug content was measured at various time intervals. Conclusion: It was concluded that in PBS media after 75 h, 85, 95 and 98% of loaded doxycycline released, respectively, from the sample containing 22, 32 and 35% of the drug. In SBF media, the release was slower and after 350 h, 82, 91 and 95% of loaded doxycycline released from the samples, respectively, containing 22, 32 and 35 % of the drug. The results of this study indicated that by use of drugreleasing profile and selecting appropriate carrier dose, the released amount of the drug into the patient body can be controlled." @default.
- W2893763469 created "2018-10-05" @default.
- W2893763469 creator A5044361337 @default.
- W2893763469 creator A5066400792 @default.
- W2893763469 date "2018-11-27" @default.
- W2893763469 modified "2023-09-27" @default.
- W2893763469 title "Controlled Release of Doxycycline by Magnetized Microporous MIL53(Fe); Focus on Magnetization and Drug Loading" @default.
- W2893763469 cites W1979511622 @default.
- W2893763469 cites W1987504473 @default.
- W2893763469 cites W1993054776 @default.
- W2893763469 cites W2008520153 @default.
- W2893763469 cites W2023134965 @default.
- W2893763469 cites W2051504085 @default.
- W2893763469 cites W2064036692 @default.
- W2893763469 cites W2066991705 @default.
- W2893763469 cites W2077349878 @default.
- W2893763469 cites W2083001124 @default.
- W2893763469 cites W2083966793 @default.
- W2893763469 cites W2091211077 @default.
- W2893763469 cites W2131762032 @default.
- W2893763469 cites W2136135866 @default.
- W2893763469 cites W2170811673 @default.
- W2893763469 cites W2287084906 @default.
- W2893763469 cites W2322498174 @default.
- W2893763469 cites W2613803523 @default.
- W2893763469 doi "https://doi.org/10.2174/1567201815666180926120525" @default.
- W2893763469 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30255757" @default.
- W2893763469 hasPublicationYear "2018" @default.
- W2893763469 type Work @default.
- W2893763469 sameAs 2893763469 @default.
- W2893763469 citedByCount "2" @default.
- W2893763469 countsByYear W28937634692020 @default.
- W2893763469 crossrefType "journal-article" @default.
- W2893763469 hasAuthorship W2893763469A5044361337 @default.
- W2893763469 hasAuthorship W2893763469A5066400792 @default.
- W2893763469 hasConcept C13965031 @default.
- W2893763469 hasConcept C163588942 @default.
- W2893763469 hasConcept C171250308 @default.
- W2893763469 hasConcept C178790620 @default.
- W2893763469 hasConcept C185592680 @default.
- W2893763469 hasConcept C192562407 @default.
- W2893763469 hasConcept C2777179404 @default.
- W2893763469 hasConcept C2779820397 @default.
- W2893763469 hasConcept C2780035454 @default.
- W2893763469 hasConcept C43617362 @default.
- W2893763469 hasConcept C501593827 @default.
- W2893763469 hasConcept C55493867 @default.
- W2893763469 hasConcept C71924100 @default.
- W2893763469 hasConcept C86381522 @default.
- W2893763469 hasConcept C96616956 @default.
- W2893763469 hasConcept C98274493 @default.
- W2893763469 hasConceptScore W2893763469C13965031 @default.
- W2893763469 hasConceptScore W2893763469C163588942 @default.
- W2893763469 hasConceptScore W2893763469C171250308 @default.
- W2893763469 hasConceptScore W2893763469C178790620 @default.
- W2893763469 hasConceptScore W2893763469C185592680 @default.
- W2893763469 hasConceptScore W2893763469C192562407 @default.
- W2893763469 hasConceptScore W2893763469C2777179404 @default.
- W2893763469 hasConceptScore W2893763469C2779820397 @default.
- W2893763469 hasConceptScore W2893763469C2780035454 @default.
- W2893763469 hasConceptScore W2893763469C43617362 @default.
- W2893763469 hasConceptScore W2893763469C501593827 @default.
- W2893763469 hasConceptScore W2893763469C55493867 @default.
- W2893763469 hasConceptScore W2893763469C71924100 @default.
- W2893763469 hasConceptScore W2893763469C86381522 @default.
- W2893763469 hasConceptScore W2893763469C96616956 @default.
- W2893763469 hasConceptScore W2893763469C98274493 @default.
- W2893763469 hasLocation W28937634691 @default.
- W2893763469 hasLocation W28937634692 @default.
- W2893763469 hasOpenAccess W2893763469 @default.
- W2893763469 hasPrimaryLocation W28937634691 @default.
- W2893763469 hasRelatedWork W1823516074 @default.
- W2893763469 hasRelatedWork W1984284675 @default.
- W2893763469 hasRelatedWork W2061955697 @default.
- W2893763469 hasRelatedWork W2069859065 @default.
- W2893763469 hasRelatedWork W2093782571 @default.
- W2893763469 hasRelatedWork W2337597952 @default.
- W2893763469 hasRelatedWork W2500014688 @default.
- W2893763469 hasRelatedWork W2893763469 @default.
- W2893763469 hasRelatedWork W3023582450 @default.
- W2893763469 hasRelatedWork W3089060975 @default.
- W2893763469 isParatext "false" @default.
- W2893763469 isRetracted "false" @default.
- W2893763469 magId "2893763469" @default.
- W2893763469 workType "article" @default.