FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893768111> ?p ?o ?g. }

• W2893768111 endingPage "704" @default.
• W2893768111 startingPage "698" @default.
• W2893768111 abstract "Background: Care for patients with Marfan syndrome (MFS) has improved substantially in recent decades. Increasing clinical knowledge and genetic analysis allow early diagnosis of the disease in childhood. Because of the earlier initiation to preventive and medical treatment, patients’ life expectancy has risen. To ensure optimal care, pediatric patients require a safe follow-up regime, multidisciplinary care, and a safe transition to adult care. Methods: We collected a sample of 149 pediatric Marfan patients, of whom 34 patients had already been transferred to adult care or who were currently transitioning. First, we evaluated clinical aspects of patients that manifest in childhood and are present in the transition process. Second, we analyzed the transition process itself. Results: We found age-dependent manifestation of organ pathologies. Dilatation of the sinus of Valsalva showed a particularly high prevalence during the transition process and 62% of patients required medical treatment. Mean onset of aortic root dilatation was 9.9±5.8 years. Concerning systemic manifestation in MFS skin striae, wrist and thumb sign, and reduced elbow extension occurred significantly more often in patients who were transitioning than in younger children with MFS. All other clinical Marfan features showed an increased prevalence in patients who were transitioning compared with younger patients. In our cohort, transition was successful in 20 patients (58.9%), 12 patients (35.3%) are still in the transition process and 2 patients (5.9%) were lost to follow up. Conclusions: Marfan patients in the transition process are already under a chronic disease condition with a high onset of especially cardiovascular pathologies. Although early medical treatment in childhood is effective, the pathologies of the connective tissue require lifelong attention and influence life in many ways. The big challenge during transition is the double change of responsibility from the parents and pediatric doctor to the patient and adult doctor. Consequently, patients in transition process require special attention and close contact with the doctor and the family. A reevaluation by the supervising pediatric Marfan specialist of the successful transition to adult care is indispensable before the pediatric care of Marfan patients is completed." @default.
• W2893768111 created "2018-10-05" @default.
• W2893768111 creator A5006272403 @default.
• W2893768111 creator A5013698850 @default.
• W2893768111 creator A5030537780 @default.
• W2893768111 creator A5036959211 @default.
• W2893768111 creator A5047858406 @default.
• W2893768111 creator A5050599121 @default.
• W2893768111 creator A5065585408 @default.
• W2893768111 creator A5073790489 @default.
• W2893768111 creator A5074232635 @default.
• W2893768111 date "2018-12-01" @default.
• W2893768111 modified "2023-10-10" @default.
• W2893768111 title "The transition of pediatric Marfan patients to adult care: a challenge and its risks" @default.
• W2893768111 cites W1599695532 @default.
• W2893768111 cites W1762381998 @default.
• W2893768111 cites W1987449317 @default.
• W2893768111 cites W1987891430 @default.
• W2893768111 cites W1992806153 @default.
• W2893768111 cites W2008206457 @default.
• W2893768111 cites W2021557585 @default.
• W2893768111 cites W2089917305 @default.
• W2893768111 cites W2097667460 @default.
• W2893768111 cites W2100310445 @default.
• W2893768111 cites W2112535798 @default.
• W2893768111 cites W2113779039 @default.
• W2893768111 cites W2131202416 @default.
• W2893768111 cites W2135348048 @default.
• W2893768111 cites W2145661830 @default.
• W2893768111 cites W2157048147 @default.
• W2893768111 cites W2158586772 @default.
• W2893768111 cites W2181221068 @default.
• W2893768111 cites W2229173471 @default.
• W2893768111 cites W2325125905 @default.
• W2893768111 cites W2346049830 @default.
• W2893768111 cites W2415119013 @default.
• W2893768111 cites W2548693679 @default.
• W2893768111 cites W2552522008 @default.
• W2893768111 doi "https://doi.org/10.21037/cdt.2018.09.13" @default.
• W2893768111 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6331371" @default.
• W2893768111 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30740317" @default.
• W2893768111 hasPublicationYear "2018" @default.
• W2893768111 type Work @default.
• W2893768111 sameAs 2893768111 @default.
• W2893768111 citedByCount "7" @default.
• W2893768111 countsByYear W28937681112020 @default.
• W2893768111 countsByYear W28937681112021 @default.
• W2893768111 countsByYear W28937681112022 @default.
• W2893768111 countsByYear W28937681112023 @default.
• W2893768111 crossrefType "journal-article" @default.
• W2893768111 hasAuthorship W2893768111A5006272403 @default.
• W2893768111 hasAuthorship W2893768111A5013698850 @default.
• W2893768111 hasAuthorship W2893768111A5030537780 @default.
• W2893768111 hasAuthorship W2893768111A5036959211 @default.
• W2893768111 hasAuthorship W2893768111A5047858406 @default.
• W2893768111 hasAuthorship W2893768111A5050599121 @default.
• W2893768111 hasAuthorship W2893768111A5065585408 @default.
• W2893768111 hasAuthorship W2893768111A5073790489 @default.
• W2893768111 hasAuthorship W2893768111A5074232635 @default.
• W2893768111 hasBestOaLocation W28937681111 @default.
• W2893768111 hasConcept C126322002 @default.
• W2893768111 hasConcept C141071460 @default.
• W2893768111 hasConcept C187212893 @default.
• W2893768111 hasConcept C194828623 @default.
• W2893768111 hasConcept C205545832 @default.
• W2893768111 hasConcept C2779134260 @default.
• W2893768111 hasConcept C2780561598 @default.
• W2893768111 hasConcept C3018838755 @default.
• W2893768111 hasConcept C71924100 @default.
• W2893768111 hasConcept C72563966 @default.
• W2893768111 hasConceptScore W2893768111C126322002 @default.
• W2893768111 hasConceptScore W2893768111C141071460 @default.
• W2893768111 hasConceptScore W2893768111C187212893 @default.
• W2893768111 hasConceptScore W2893768111C194828623 @default.
• W2893768111 hasConceptScore W2893768111C205545832 @default.
• W2893768111 hasConceptScore W2893768111C2779134260 @default.
• W2893768111 hasConceptScore W2893768111C2780561598 @default.
• W2893768111 hasConceptScore W2893768111C3018838755 @default.
• W2893768111 hasConceptScore W2893768111C71924100 @default.
• W2893768111 hasConceptScore W2893768111C72563966 @default.
• W2893768111 hasIssue "6" @default.
• W2893768111 hasLocation W28937681111 @default.
• W2893768111 hasLocation W28937681112 @default.
• W2893768111 hasLocation W28937681113 @default.
• W2893768111 hasLocation W28937681114 @default.
• W2893768111 hasOpenAccess W2893768111 @default.
• W2893768111 hasPrimaryLocation W28937681111 @default.
• W2893768111 hasRelatedWork W2027902536 @default.
• W2893768111 hasRelatedWork W2035682242 @default.
• W2893768111 hasRelatedWork W2071535500 @default.
• W2893768111 hasRelatedWork W2315085516 @default.
• W2893768111 hasRelatedWork W2316407790 @default.
• W2893768111 hasRelatedWork W2386452954 @default.
• W2893768111 hasRelatedWork W2603773853 @default.
• W2893768111 hasRelatedWork W2736827820 @default.
• W2893768111 hasRelatedWork W2946626537 @default.
• W2893768111 hasRelatedWork W2952239533 @default.
• W2893768111 hasVolume "8" @default.

• next