FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893775342> ?p ?o ?g. }

• W2893775342 endingPage "170" @default.
• W2893775342 startingPage "160" @default.
• W2893775342 abstract "Late-life depression (LLD) has been associated with alterations in intrinsic functional networks, best characterized in the default mode network (DMN), cognitive control network (CCN), and salience network. However, these findings often derive from small samples, and it is not well understood how network findings relate to clinical and cognitive symptomatology. We studied 100 older adults (n = 79 with LLD, n = 21 nondepressed) and collected resting-state functional magnetic resonance imaging, clinical measures of depression, and performance on cognitive tests. We selected canonical network regions for each intrinsic functional network (DMN, CCN, and salience network) as seeds in seed-to-voxel analysis. We compared connectivity between the depressed and nondepressed groups and correlated connectivity with depression severity among depressed subjects. We then investigated whether the observed connectivity findings were associated with greater severity of common neuropsychiatric symptoms or poorer cognitive performance. LLD was characterized by decreased DMN connectivity to the frontal pole, a CCN region (Wald χ21 = 22.33, p < .001). No significant group differences in connectivity were found for the CCN or salience network. However, in the LLD group, increased CCN connectivity was associated with increased depression severity (Wald χ21 > 20.14, p < .001), greater anhedonia (Wald χ21 = 7.02, p = .008) and fatigue (Wald χ21 = 6.31, p = .012), and poorer performance on tests of episodic memory (Wald χ21 > 4.65, p < .031), executive function (Wald χ21 = 7.18, p = .007), and working memory (Wald χ21 > 4.29, p < .038). LLD is characterized by differences in DMN connectivity, while CCN connectivity is associated with LLD symptomology, including poorer performance in several cognitive domains." @default.
• W2893775342 created "2018-10-05" @default.
• W2893775342 creator A5007036346 @default.
• W2893775342 creator A5007819776 @default.
• W2893775342 creator A5024657657 @default.
• W2893775342 creator A5036545204 @default.
• W2893775342 creator A5070955629 @default.
• W2893775342 creator A5074653018 @default.
• W2893775342 creator A5075735203 @default.
• W2893775342 creator A5082289456 @default.
• W2893775342 creator A5089435052 @default.
• W2893775342 date "2019-02-01" @default.
• W2893775342 modified "2023-10-14" @default.
• W2893775342 title "Intrinsic Functional Network Connectivity Is Associated With Clinical Symptoms and Cognition in Late-Life Depression" @default.
• W2893775342 cites W1040825594 @default.
• W2893775342 cites W1977645227 @default.
• W2893775342 cites W1978694642 @default.
• W2893775342 cites W1982921548 @default.
• W2893775342 cites W1991771535 @default.
• W2893775342 cites W1999520265 @default.
• W2893775342 cites W2001866454 @default.
• W2893775342 cites W2004826931 @default.
• W2893775342 cites W2014617960 @default.
• W2893775342 cites W2015741558 @default.
• W2893775342 cites W2017230032 @default.
• W2893775342 cites W2017407197 @default.
• W2893775342 cites W2017918288 @default.
• W2893775342 cites W2020259042 @default.
• W2893775342 cites W2026403155 @default.
• W2893775342 cites W2026482820 @default.
• W2893775342 cites W2037229172 @default.
• W2893775342 cites W2066208486 @default.
• W2893775342 cites W2083730492 @default.
• W2893775342 cites W2095438393 @default.
• W2893775342 cites W2098575003 @default.
• W2893775342 cites W2102364469 @default.
• W2893775342 cites W2102848905 @default.
• W2893775342 cites W2114242035 @default.
• W2893775342 cites W2116658855 @default.
• W2893775342 cites W2120781542 @default.
• W2893775342 cites W2122030287 @default.
• W2893775342 cites W2126960774 @default.
• W2893775342 cites W2131398580 @default.
• W2893775342 cites W2131823335 @default.
• W2893775342 cites W2136435696 @default.
• W2893775342 cites W2145729305 @default.
• W2893775342 cites W2146146069 @default.
• W2893775342 cites W2150111222 @default.
• W2893775342 cites W2158327608 @default.
• W2893775342 cites W2162010696 @default.
• W2893775342 cites W2163709153 @default.
• W2893775342 cites W2164865187 @default.
• W2893775342 cites W2165758561 @default.
• W2893775342 cites W2169442707 @default.
• W2893775342 cites W2170796144 @default.
• W2893775342 cites W2414922822 @default.
• W2893775342 cites W2561379698 @default.
• W2893775342 cites W2596415428 @default.
• W2893775342 cites W2952135827 @default.
• W2893775342 cites W585108207 @default.
• W2893775342 doi "https://doi.org/10.1016/j.bpsc.2018.09.003" @default.
• W2893775342 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6368882" @default.
• W2893775342 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30392844" @default.
• W2893775342 hasPublicationYear "2019" @default.
• W2893775342 type Work @default.
• W2893775342 sameAs 2893775342 @default.
• W2893775342 citedByCount "28" @default.
• W2893775342 countsByYear W28937753422019 @default.
• W2893775342 countsByYear W28937753422020 @default.
• W2893775342 countsByYear W28937753422021 @default.
• W2893775342 countsByYear W28937753422022 @default.
• W2893775342 countsByYear W28937753422023 @default.
• W2893775342 crossrefType "journal-article" @default.
• W2893775342 hasAuthorship W2893775342A5007036346 @default.
• W2893775342 hasAuthorship W2893775342A5007819776 @default.
• W2893775342 hasAuthorship W2893775342A5024657657 @default.
• W2893775342 hasAuthorship W2893775342A5036545204 @default.
• W2893775342 hasAuthorship W2893775342A5070955629 @default.
• W2893775342 hasAuthorship W2893775342A5074653018 @default.
• W2893775342 hasAuthorship W2893775342A5075735203 @default.
• W2893775342 hasAuthorship W2893775342A5082289456 @default.
• W2893775342 hasAuthorship W2893775342A5089435052 @default.
• W2893775342 hasBestOaLocation W28937753422 @default.
• W2893775342 hasConcept C108154423 @default.
• W2893775342 hasConcept C118552586 @default.
• W2893775342 hasConcept C126322002 @default.
• W2893775342 hasConcept C139719470 @default.
• W2893775342 hasConcept C141516989 @default.
• W2893775342 hasConcept C15744967 @default.
• W2893775342 hasConcept C162324750 @default.
• W2893775342 hasConcept C169760540 @default.
• W2893775342 hasConcept C169900460 @default.
• W2893775342 hasConcept C185711340 @default.
• W2893775342 hasConcept C2776412080 @default.
• W2893775342 hasConcept C2776867660 @default.
• W2893775342 hasConcept C2778941446 @default.
• W2893775342 hasConcept C2779226451 @default.
• W2893775342 hasConcept C2781357127 @default.

• next