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• W2893786413 abstract "Eicosapentaenoic acid (EPA)-derived resolvin E1 (RvE1) and E2 (RvE2) have antidepressant effects. Here, we investigated the antidepressant effects of resolvin E3 (RvE3) in a mouse model of lipopolysaccharide (LPS)-induced depression. We observed that LPS (0.8 mg/kg, i.p.) significantly increased immobility time on the tail suspension test, and this depression-like behavior was dose-dependently attenuated by intracerebroventricular infusion of RvE3 (10 or 100 ng). No effects of LPS or intracerebroventricular infusion of RvE3 on locomotor activity were observed. These results indicate that RvE3, as well as RvE1 and RvE2, have antidepressant effects." @default.
• W2893786413 created "2018-10-05" @default.
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• W2893786413 date "2018-09-01" @default.
• W2893786413 modified "2023-10-03" @default.
• W2893786413 title "Resolvin E3 attenuates lipopolysaccharide-induced depression-like behavior in mice" @default.
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• W2893786413 doi "https://doi.org/10.1016/j.jphs.2018.09.006" @default.
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