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- W2893790047 abstract "A short and efficient synthesis of the nucleoside fragment contained in the NS5B nucleoside inhibitor BMS-986094 was achieved in 23% overall yield on a gram scale. The synthesis uses the widely available starting material guanosine via a short sequence ending in a Mukaiyama hydration reaction to establish the key tertiary alcohol moiety and set the C-2' methyl stereogenic center. This work resulted in a robust and scalable approach to this complex nucleoside." @default.
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- W2893790047 date "2018-09-25" @default.
- W2893790047 modified "2023-10-18" @default.
- W2893790047 title "Synthesis of 2′-Methyl-6-methoxyguanosine from the Parent Ribonucleoside Guanosine" @default.
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- W2893790047 doi "https://doi.org/10.1021/acs.joc.8b02194" @default.
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