FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893798802> ?p ?o ?g. }

• W2893798802 endingPage "6694" @default.
• W2893798802 startingPage "6688" @default.
• W2893798802 abstract "BACKGROUND:The optimal medical regimen for managing hypertension during acute phase of lacunar infarcts has not yet been clarified in real world setting. The aim of this study was to evaluate blood pressure lowering regimens on neurological progression and clinical outcomes during the acute phase of lacunar infarcts. MATERIAL AND METHODS:For this study, 411 patients with first-episode lacunar infarcts and hypertension within 24 hours of symptom onset were included. All patients received antihypertension therapies, with different regimens, as well as routine medication during first 7 days after onset. There were 6 proposed antihypertensive treatments: calcium channel blockers (CCB), angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB), β-blocker (β-B), and diuretic drug (DD) alone or in combination. Neurological progression was defined as worsening by ≥1 point in the National Institute of Health Stroke Scale (NIHSS) for motor function. The outcome was assessed using the modified Rankin Scale (mRS): favorable outcome (mRS of 0–1) or unfavorable outcome (mRS 2–5). RESULTS:Logistic regression analysis showed that combination therapy with CCB, ACEI/ARB, and β-B exhibited the lowest risk of deterioration (OR=0.48, P=0.019) and unfavorable outcomes (OR=0.50, P=0.022). Similarly, combination therapy with CCB, ACEI/ARB, and DD exhibited lower risk of deterioration (OR=0.63, P=0.033) and unfavorable outcome (OR=0.77, P=0.042) at 3 months. CONCLUSIONS:Rational blood pressure lowering was beneficial to the functional outcomes of patients during acute phase of lacunar infarcts, and combination therapy was better than mono-drug therapy." @default.
• W2893798802 created "2018-10-05" @default.
• W2893798802 creator A5022475471 @default.
• W2893798802 creator A5026856159 @default.
• W2893798802 creator A5037751669 @default.
• W2893798802 creator A5045545412 @default.
• W2893798802 creator A5065047387 @default.
• W2893798802 creator A5066669793 @default.
• W2893798802 creator A5074891065 @default.
• W2893798802 creator A5089640773 @default.
• W2893798802 date "2018-09-22" @default.
• W2893798802 modified "2023-09-23" @default.
• W2893798802 title "Antihypertensive Therapy in the Acute Phase of Lacunar Infarcts" @default.
• W2893798802 cites W1508897604 @default.
• W2893798802 cites W1519546416 @default.
• W2893798802 cites W1521700123 @default.
• W2893798802 cites W2001184053 @default.
• W2893798802 cites W2013636105 @default.
• W2893798802 cites W2016879813 @default.
• W2893798802 cites W2017021232 @default.
• W2893798802 cites W2024956494 @default.
• W2893798802 cites W2053958187 @default.
• W2893798802 cites W2073060714 @default.
• W2893798802 cites W2082551533 @default.
• W2893798802 cites W2086199925 @default.
• W2893798802 cites W2090083795 @default.
• W2893798802 cites W2117701155 @default.
• W2893798802 cites W2117827372 @default.
• W2893798802 cites W2123312526 @default.
• W2893798802 cites W2130257014 @default.
• W2893798802 cites W2141090888 @default.
• W2893798802 cites W2160919385 @default.
• W2893798802 cites W2163053670 @default.
• W2893798802 cites W2164866146 @default.
• W2893798802 cites W2415676059 @default.
• W2893798802 cites W2540051069 @default.
• W2893798802 cites W3151176453 @default.
• W2893798802 doi "https://doi.org/10.12659/msm.910183" @default.
• W2893798802 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6166525" @default.
• W2893798802 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30243025" @default.
• W2893798802 hasPublicationYear "2018" @default.
• W2893798802 type Work @default.
• W2893798802 sameAs 2893798802 @default.
• W2893798802 citedByCount "1" @default.
• W2893798802 countsByYear W28937988022021 @default.
• W2893798802 crossrefType "journal-article" @default.
• W2893798802 hasAuthorship W2893798802A5022475471 @default.
• W2893798802 hasAuthorship W2893798802A5026856159 @default.
• W2893798802 hasAuthorship W2893798802A5037751669 @default.
• W2893798802 hasAuthorship W2893798802A5045545412 @default.
• W2893798802 hasAuthorship W2893798802A5065047387 @default.
• W2893798802 hasAuthorship W2893798802A5066669793 @default.
• W2893798802 hasAuthorship W2893798802A5074891065 @default.
• W2893798802 hasAuthorship W2893798802A5089640773 @default.
• W2893798802 hasBestOaLocation W28937988022 @default.
• W2893798802 hasConcept C126322002 @default.
• W2893798802 hasConcept C127413603 @default.
• W2893798802 hasConcept C164705383 @default.
• W2893798802 hasConcept C27016395 @default.
• W2893798802 hasConcept C2776999253 @default.
• W2893798802 hasConcept C2777798775 @default.
• W2893798802 hasConcept C2779285336 @default.
• W2893798802 hasConcept C2779918671 @default.
• W2893798802 hasConcept C2780645631 @default.
• W2893798802 hasConcept C2780931571 @default.
• W2893798802 hasConcept C2781413609 @default.
• W2893798802 hasConcept C3020199598 @default.
• W2893798802 hasConcept C3020298707 @default.
• W2893798802 hasConcept C500558357 @default.
• W2893798802 hasConcept C541997718 @default.
• W2893798802 hasConcept C71924100 @default.
• W2893798802 hasConcept C78519656 @default.
• W2893798802 hasConcept C84393581 @default.
• W2893798802 hasConceptScore W2893798802C126322002 @default.
• W2893798802 hasConceptScore W2893798802C127413603 @default.
• W2893798802 hasConceptScore W2893798802C164705383 @default.
• W2893798802 hasConceptScore W2893798802C27016395 @default.
• W2893798802 hasConceptScore W2893798802C2776999253 @default.
• W2893798802 hasConceptScore W2893798802C2777798775 @default.
• W2893798802 hasConceptScore W2893798802C2779285336 @default.
• W2893798802 hasConceptScore W2893798802C2779918671 @default.
• W2893798802 hasConceptScore W2893798802C2780645631 @default.
• W2893798802 hasConceptScore W2893798802C2780931571 @default.
• W2893798802 hasConceptScore W2893798802C2781413609 @default.
• W2893798802 hasConceptScore W2893798802C3020199598 @default.
• W2893798802 hasConceptScore W2893798802C3020298707 @default.
• W2893798802 hasConceptScore W2893798802C500558357 @default.
• W2893798802 hasConceptScore W2893798802C541997718 @default.
• W2893798802 hasConceptScore W2893798802C71924100 @default.
• W2893798802 hasConceptScore W2893798802C78519656 @default.
• W2893798802 hasConceptScore W2893798802C84393581 @default.
• W2893798802 hasLocation W28937988021 @default.
• W2893798802 hasLocation W28937988022 @default.
• W2893798802 hasLocation W28937988023 @default.
• W2893798802 hasLocation W28937988024 @default.
• W2893798802 hasOpenAccess W2893798802 @default.
• W2893798802 hasPrimaryLocation W28937988021 @default.
• W2893798802 hasRelatedWork W2004283873 @default.

• next