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• W2893812768 abstract "All above ground plant organs initiate or derive from stem cells at the shoot apical meristem. The activity of the shoot apical meristem determines the rate of leaf initiation, which is repressed by the ACTIN RELATED PROTEIN2/3 (ARP2/3) complex in the dark. The ARP2/3 complex is an ancient nucleator of actin filament branches, with roles in a variety of subcellular processes. However, the mechanism by which the ARP2/3 complex regulates shoot apical meristem activity is unknown.In this thesis I show that the increased shoot apical meristem activity of arp3 in prolonged darkness required the polar auxin efflux carrier PIN-FORMED1 (PIN1). Wild-type shoot apical meristem activity was largely unaffected by inhibitors of polar auxin transport in the dark, and a pin1 mutant had similar shoot apical meristem activity to wild-type. By stark contrast, the increased shoot apical meristem activity of arp3 was hypersensitive to inhibitors of polar auxin transport, and abolished in an arp3pin1 double mutant. Furthermore, multiple phenotypes of a brassinosteroid biosynthesis mutant det2, reported to have reduced PIN1 expression and polar auxin transport, were rescued in an arp3det2 double mutant grown in the light. These results indicate that the ARP2/3 complex regulates the activity of PIN1, possibly by facilitating PIN1 endocytosis, and suggest that the ARP2/3 complex is a repressor of brassinosteroid responses. The auxin response factors ARF4 and ARF5 were found to be repressors of shoot apical meristem activity in the same pathway as the ARP2/3 complex. This result led to the proposal of a model where auxin minima, rather than auxin maxima (where ARF4 and ARF5 are active) are required to initiate new leaves at the shoot apical meristem.The increased shoot apical meristem activity of arp3 required sugar, the glucose sensor TOR kinase, and the initial steps of glycolysis which generate precursors for cell wall biosynthesis.In a candidate approach to identify novel transcriptional regulators of dark development, the IND transcription factor was found to repress shoot apical meristem activity redundantly with its homologue HEC2. IND was also found to interact genetically with the phytochrome interacting factors PIF3 and PIF4 to differentially regulate shoot apical meristem activity. Microarray analysis revealed that the primary target of IND is the sugar transporter SWEET15 (upregulated), which promoted shoot apical meristem activity.This research identifies potential avenues for generating crop varieties with increased shoot apical meristem activity in the dark, which might be advantageous in a mulched system, and for generating semi-dwarf crop varieties, by activating a subset of brassinosteroid responses in brassinosteroid deficient crops." @default.
• W2893812768 created "2018-10-05" @default.
• W2893812768 creator A5056787313 @default.
• W2893812768 date "2017-11-01" @default.
• W2893812768 modified "2023-09-23" @default.
• W2893812768 title "Regulation of shoot apical meristem activity" @default.
• W2893812768 cites W1269030518 @default.
• W2893812768 cites W1409738226 @default.
• W2893812768 cites W1489896494 @default.
• W2893812768 cites W1491386330 @default.
• W2893812768 cites W149471616 @default.
• W2893812768 cites W1501889797 @default.
• W2893812768 cites W1504446821 @default.
• W2893812768 cites W1505402460 @default.
• W2893812768 cites W1510830988 @default.
• W2893812768 cites W1511539511 @default.
• W2893812768 cites W1518139443 @default.
• W2893812768 cites W1527485748 @default.
• W2893812768 cites W1532356633 @default.
• W2893812768 cites W1543768950 @default.
• W2893812768 cites W1561407807 @default.
• W2893812768 cites W1563726840 @default.
• W2893812768 cites W1601965827 @default.
• W2893812768 cites W1606831709 @default.
• W2893812768 cites W1717529539 @default.
• W2893812768 cites W1722998888 @default.
• W2893812768 cites W1787264146 @default.
• W2893812768 cites W1864021403 @default.
• W2893812768 cites W1873185334 @default.
• W2893812768 cites W1897890421 @default.
• W2893812768 cites W1918432312 @default.
• W2893812768 cites W1938843681 @default.
• W2893812768 cites W1953502506 @default.
• W2893812768 cites W1963978545 @default.
• W2893812768 cites W1964083750 @default.
• W2893812768 cites W1964775981 @default.
• W2893812768 cites W1964846007 @default.
• W2893812768 cites W1965234951 @default.
• W2893812768 cites W1966163069 @default.
• W2893812768 cites W1966562148 @default.
• W2893812768 cites W1966633842 @default.
• W2893812768 cites W1967554559 @default.
• W2893812768 cites W1967710126 @default.
• W2893812768 cites W1967955638 @default.
• W2893812768 cites W1968503465 @default.
• W2893812768 cites W1968661759 @default.
• W2893812768 cites W1968706891 @default.
• W2893812768 cites W1969591602 @default.
• W2893812768 cites W1969827811 @default.
• W2893812768 cites W1970208055 @default.
• W2893812768 cites W1971615018 @default.
• W2893812768 cites W1971910567 @default.
• W2893812768 cites W1972325884 @default.
• W2893812768 cites W1973109304 @default.
• W2893812768 cites W1973614455 @default.
• W2893812768 cites W1974001143 @default.
• W2893812768 cites W1974631465 @default.
• W2893812768 cites W1975053636 @default.
• W2893812768 cites W1975288257 @default.
• W2893812768 cites W1975473523 @default.
• W2893812768 cites W1975920666 @default.
• W2893812768 cites W1978892165 @default.
• W2893812768 cites W1979699650 @default.
• W2893812768 cites W1979742084 @default.
• W2893812768 cites W1981388828 @default.
• W2893812768 cites W1981453623 @default.
• W2893812768 cites W1981523943 @default.
• W2893812768 cites W1981587197 @default.
• W2893812768 cites W1981663912 @default.
• W2893812768 cites W1981789729 @default.
• W2893812768 cites W1982573383 @default.
• W2893812768 cites W1984559046 @default.
• W2893812768 cites W1986085289 @default.
• W2893812768 cites W1986100014 @default.
• W2893812768 cites W1986352294 @default.
• W2893812768 cites W1986630228 @default.
• W2893812768 cites W1986950157 @default.
• W2893812768 cites W1989326780 @default.
• W2893812768 cites W1990030630 @default.
• W2893812768 cites W1990208478 @default.
• W2893812768 cites W1991617619 @default.
• W2893812768 cites W1991883784 @default.
• W2893812768 cites W1992396194 @default.
• W2893812768 cites W1992440587 @default.
• W2893812768 cites W1992684889 @default.
• W2893812768 cites W1992932809 @default.
• W2893812768 cites W1993566688 @default.
• W2893812768 cites W1993969626 @default.
• W2893812768 cites W1994148506 @default.
• W2893812768 cites W1994207647 @default.
• W2893812768 cites W1994700942 @default.
• W2893812768 cites W1996708080 @default.
• W2893812768 cites W1997230083 @default.
• W2893812768 cites W1997530089 @default.
• W2893812768 cites W1997724869 @default.
• W2893812768 cites W1998292202 @default.
• W2893812768 cites W1999717088 @default.
• W2893812768 cites W2000171922 @default.
• W2893812768 cites W2000913872 @default.
• W2893812768 cites W2001639563 @default.

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