Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893814272> ?p ?o ?g. }
- W2893814272 abstract "MicroRNAs (miRs) are small molecules important for regulation of transcription and translation. The objective was to identify hormonally-regulated miRs in human endometrial stromal cells and to determine the impact of the endocrine disruptor, bisphenol A (BPA), on those miRs. miR microarray analysis and multiple confirmatory cell preparations treated with 17β-estradiol (E2) and BPA altered miR-27b, let-7c, let-7e, and miR-181b. Further, decidualization downregulated miR-27b. VEGFB and VEGFC were validated as targets of miR-27b. Identification of miR-27b target genes suggests that BPA and E2 downregulate miR-27b thereby leading to upregulation of genes important for vascularization and angiogenesis of the endometrium during the menstrual cycle and decidualization." @default.
- W2893814272 created "2018-10-05" @default.
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- W2893814272 date "2018-09-01" @default.
- W2893814272 modified "2023-10-16" @default.
- W2893814272 title "ESTROGEN-REGULATED miRNA-27b IS ALTERED BY BISPHENOL A IN ENDOMETRIAL STROMAL CELLS" @default.
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- W2893814272 doi "https://doi.org/10.1530/rep-18-0041" @default.
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