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- W2893829449 abstract "Significance Changes in the number and/or structure of chromosomes (i.e., chromosomal rearrangements) have the potential to drive speciation. However, their accumulation in a population is considered both difficult and unpredictable, because the greatly reduced reproductive fitness of chromosomal hybrids prevents fixation of novel karyotypes. Here, we provide evidence for a mechanism that rescues fertility of chromosomal hybrids in species with holocentric chromosomes. We demonstrate that chromosomal heterozygotes of Leptidea Wood White butterflies have a reverse order of main meiotic events in which the first and most critical stage of the chromosome number reduction is replaced by the less risky stage of sister chromatid separation. This may facilitate long-term persistence of chromosomal rearrangements, which is a major prerequisite for chromosomal speciation." @default.
- W2893829449 created "2018-10-05" @default.
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- W2893829449 date "2018-09-28" @default.
- W2893829449 modified "2023-10-09" @default.
- W2893829449 title "Versatility of multivalent orientation, inverted meiosis, and rescued fitness in holocentric chromosomal hybrids" @default.
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- W2893829449 doi "https://doi.org/10.1073/pnas.1802610115" @default.
- W2893829449 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6187165" @default.
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