FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893833939> ?p ?o ?g. }

• W2893833939 endingPage "115" @default.
• W2893833939 startingPage "108" @default.
• W2893833939 abstract "This investigation was undertaken to compare the sensitization/conditioned effects induced by apomorphine given pre-trial versus administered immediately post-trial or 15 min post-trial. We measured the effects on locomotor activity of 5 daily apomorphine treatments induced by an inhibitory low auto-receptor dose (0.05 mg/kg) and a stimulatory high postsynaptic dose (2.0 mg/kg). Three sets of four groups were used and each set of four groups was comprised of two vehicle and two apomorphine groups (0.05/2.0 apomorphine). The only difference among the three sets of four groups was when the treatments were administered relative to placement in the novel environment. One set received the treatment pre-test, another set was injected immediately after and the third set injected 15 min after 5 min test sessions in a novel environment. The repeated pre and immediate post-test apomorphine treatments induced locomotor sensitization over the 5 days of treatment. The low dose pre and immediate post-test treatments progressively decreased locomotion and the high dose pre and immediate post-test progressively increased locomotion. Critically, the tests for the immediate post-test groups were non-drug and for both the pre-test and immediate post-test groups, sensitization effects did not occur until the second test day. To control for non-associative apomorphine effects, the same apomorphine treatments were given post-test after a 15 minute delay and were found to be equivalent to vehicle. In a subsequent conditioning test, both the pre and immediate post-test low dose apomorphine groups showed conditioned behavioral inhibition and the pre and immediate post-test high dose apomorphine groups showed conditioned behavioral stimulation. We propose that the inhibitory low dose apomorphine decreased the salience/incentive of the novel environment association and thereby decreased the behavioral response and conversely that the high dose excitatory apomorphine treatment increased the salience/incentive value of the novel environment association and potentiated the behavioral response." @default.
• W2893833939 created "2018-10-05" @default.
• W2893833939 creator A5028868185 @default.
• W2893833939 creator A5076330842 @default.
• W2893833939 creator A5088579403 @default.
• W2893833939 date "2018-12-01" @default.
• W2893833939 modified "2023-10-16" @default.
• W2893833939 title "Repeated pre-trial and post-trial low and high dose apomorphine treatments induce comparable inhibitory/excitatory sensitization and conditioned drug effects" @default.
• W2893833939 cites W1582315344 @default.
• W2893833939 cites W1925492557 @default.
• W2893833939 cites W1965086517 @default.
• W2893833939 cites W1970664418 @default.
• W2893833939 cites W1975393371 @default.
• W2893833939 cites W1981603764 @default.
• W2893833939 cites W1984855945 @default.
• W2893833939 cites W1985211673 @default.
• W2893833939 cites W1993271745 @default.
• W2893833939 cites W1999596109 @default.
• W2893833939 cites W2005138253 @default.
• W2893833939 cites W2006332965 @default.
• W2893833939 cites W2021602677 @default.
• W2893833939 cites W2022867753 @default.
• W2893833939 cites W2036050112 @default.
• W2893833939 cites W2038069541 @default.
• W2893833939 cites W2038449030 @default.
• W2893833939 cites W2047987700 @default.
• W2893833939 cites W2055319462 @default.
• W2893833939 cites W2069129629 @default.
• W2893833939 cites W2069550725 @default.
• W2893833939 cites W2081411580 @default.
• W2893833939 cites W2081435274 @default.
• W2893833939 cites W2085237245 @default.
• W2893833939 cites W2092345849 @default.
• W2893833939 cites W2157844171 @default.
• W2893833939 cites W2163506350 @default.
• W2893833939 cites W2315576026 @default.
• W2893833939 cites W2604731625 @default.
• W2893833939 cites W4210955994 @default.
• W2893833939 cites W4254139634 @default.
• W2893833939 cites W4254759192 @default.
• W2893833939 doi "https://doi.org/10.1016/j.pbb.2018.09.011" @default.
• W2893833939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30267795" @default.
• W2893833939 hasPublicationYear "2018" @default.
• W2893833939 type Work @default.
• W2893833939 sameAs 2893833939 @default.
• W2893833939 citedByCount "7" @default.
• W2893833939 countsByYear W28938339392019 @default.
• W2893833939 countsByYear W28938339392020 @default.
• W2893833939 countsByYear W28938339392021 @default.
• W2893833939 countsByYear W28938339392022 @default.
• W2893833939 crossrefType "journal-article" @default.
• W2893833939 hasAuthorship W2893833939A5028868185 @default.
• W2893833939 hasAuthorship W2893833939A5076330842 @default.
• W2893833939 hasAuthorship W2893833939A5088579403 @default.
• W2893833939 hasConcept C105795698 @default.
• W2893833939 hasConcept C112592302 @default.
• W2893833939 hasConcept C126322002 @default.
• W2893833939 hasConcept C137183658 @default.
• W2893833939 hasConcept C15744967 @default.
• W2893833939 hasConcept C169760540 @default.
• W2893833939 hasConcept C17077164 @default.
• W2893833939 hasConcept C2776217527 @default.
• W2893833939 hasConcept C2777525119 @default.
• W2893833939 hasConcept C33923547 @default.
• W2893833939 hasConcept C42219234 @default.
• W2893833939 hasConcept C45262634 @default.
• W2893833939 hasConcept C513476851 @default.
• W2893833939 hasConcept C71924100 @default.
• W2893833939 hasConcept C98274493 @default.
• W2893833939 hasConcept C99476002 @default.
• W2893833939 hasConceptScore W2893833939C105795698 @default.
• W2893833939 hasConceptScore W2893833939C112592302 @default.
• W2893833939 hasConceptScore W2893833939C126322002 @default.
• W2893833939 hasConceptScore W2893833939C137183658 @default.
• W2893833939 hasConceptScore W2893833939C15744967 @default.
• W2893833939 hasConceptScore W2893833939C169760540 @default.
• W2893833939 hasConceptScore W2893833939C17077164 @default.
• W2893833939 hasConceptScore W2893833939C2776217527 @default.
• W2893833939 hasConceptScore W2893833939C2777525119 @default.
• W2893833939 hasConceptScore W2893833939C33923547 @default.
• W2893833939 hasConceptScore W2893833939C42219234 @default.
• W2893833939 hasConceptScore W2893833939C45262634 @default.
• W2893833939 hasConceptScore W2893833939C513476851 @default.
• W2893833939 hasConceptScore W2893833939C71924100 @default.
• W2893833939 hasConceptScore W2893833939C98274493 @default.
• W2893833939 hasConceptScore W2893833939C99476002 @default.
• W2893833939 hasLocation W28938339391 @default.
• W2893833939 hasLocation W28938339392 @default.
• W2893833939 hasOpenAccess W2893833939 @default.
• W2893833939 hasPrimaryLocation W28938339391 @default.
• W2893833939 hasRelatedWork W2006332965 @default.
• W2893833939 hasRelatedWork W2012943608 @default.
• W2893833939 hasRelatedWork W2039252427 @default.
• W2893833939 hasRelatedWork W2050535870 @default.
• W2893833939 hasRelatedWork W2051539462 @default.
• W2893833939 hasRelatedWork W2069129629 @default.
• W2893833939 hasRelatedWork W2069210227 @default.
• W2893833939 hasRelatedWork W2084974945 @default.

• next