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- W2893893285 abstract "OBJECTIVES:Primary Outcome:To determine the optimal comfort and co-operation among the patients for Awake fiberoptic intubation procedural sedation.Secondary Outcome:Ease of intubation, intubation time, sedation scale, comfort scores and hemodynamic variables.DESIGN:Single centre, prospective, randomized, parallel group, double blinded Study.SETTING:Department of Anaesthesiology, Tirunelveli Medical College,Tirunelveli.SUBJECT:40 patients of both sexes in the age group of 25 to 50 belonging to ASA I and II status undergoing thyroid surgery.METHODS:After randomization and masking all the subjects in the group were subjected to premedicant Inj.Glycopyrrolate and topical anaesthesia for the airway . Group D received 1 mcg/kg of dexmedetomidine followed by an infusion of 0.7 mcg/kg/hr whereas group FM received 2 mcg/kg of fentanyl and 40 mcg/kg of midazolam.MONITORING :Patient was monitored for Vital parameters, sedation score based on Ramsay sedation scale, Comfort scores based on ambu et al scoring, intubation scores.ANALYSIS & RESULTS:After recording in the master sheet, data was analysed using SPSS software, Sigma stat 3.5 version by means of student t test, one way ANOVA and chi square test. Stastical significance existed between two groups in terms of intubation time (P<0.001), sedation scale (P<0.005), comfort scores (P<0.001), hemodynamic variables (P<0.02) and SPO2 scores (P<0.02), with dexmedetomidine being the better drug among the two. Rest of the variables were comparable but not significant.CONCLUSION :Dexmedetomidine offered a good sedation, amnesia, anxiolysis, analgesia, shorter intubation time and a better hemodynamics avoiding respiratory depression when compared with fentanyl midazolam combination." @default.
- W2893893285 created "2018-10-05" @default.
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- W2893893285 date "2016-04-01" @default.
- W2893893285 modified "2023-09-27" @default.
- W2893893285 title "Comparison between Dexmedetomidine and a combination of Midazolam and Fentanyl for sedation during awake fiberoptic intubation: A prospective randomized parallel group double-blinded study" @default.
- W2893893285 hasPublicationYear "2016" @default.
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