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- W2893980600 abstract "This work demonstrates a sensitive and rapid method for the detection of antibiotic residues in food samples by employing the filtration behaviour of paper combined with aggregation and precipitation of chemical reagents. Using this concept, we successfully determined the presence of oxytetracycline and norfloxacin residues in pork using metal complexation on microfluidic paper-based analytical devices (μPADs). The base substrate (top layer of the device) was fabricated by printing letter channels of the words oxytetracycline and norfloxacin before functionalization with copper (II) sulfate pentahydrate in 0.5 M sodium hydroxide and iron (III) nitrate nanohydrate in 5 mM ammonia solution for the detection of oxytetracycline and norfloxacin separately. A transition metal hydroxide formed upon reaction that created solid precipitates on paper and allowed antibiotic residues to bind to the metal ions via coordination chemistry. The metal ion-antibiotic complex could form on the filter paper and generated a visible color change with the detection limit of 1 ppm for both oxytetracycline and norfloxacin in pork. This procedure of filtration and concentration in combination with a simple text-reporting approach allows the end users to achieve a low limit of detection as well as easy result interpretation in food safety monitoring." @default.
- W2893980600 created "2018-10-05" @default.
- W2893980600 creator A5017207356 @default.
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- W2893980600 date "2019-01-01" @default.
- W2893980600 modified "2023-10-16" @default.
- W2893980600 title "Detection of antibiotic residues in pork using paper-based microfluidic device coupled with filtration and concentration" @default.
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- W2893980600 doi "https://doi.org/10.1016/j.aca.2018.09.041" @default.
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