Matches in SemOpenAlex for { <https://semopenalex.org/work/W2893984985> ?p ?o ?g. }
- W2893984985 endingPage "374" @default.
- W2893984985 startingPage "365" @default.
- W2893984985 abstract "Despite the progress in the area of food safety, foodborne diseases still represent a massive challenge to the public health systems worldwide, mainly due to the substantial inefficiencies across the farm-to-fork continuum. Here, we report the development of a nano-carrier platform, for the targeted and precise delivery of antimicrobials for the inactivation of microorganisms on surfaces using Engineered Water Nanostructures (EWNS). An aqueous suspension of an active ingredient (AI) was used to synthesize iEWNS, with the ‘i’ denoting the AI used in their synthesis, using a combined electrospray and ionization process. The iEWNS possess unique, active-ingredient-dependent physicochemical properties: i) they are engineered to have a tunable size in the nanoscale; ii) they have excessive electric surface charge, and iii) they contain both the reactive oxygen species (ROS) formed due to the ionization of deionized (DI) water, and the AI used in their synthesis. Their charge can be used in combination with an electric field to target them onto a surface of interest. In this approach, a number of nature-inspired antimicrobials, such as H2O2, lysozyme, citric acid, and their combination, were used to synthesize a variety of iEWNS-based nano-sanitizers. It was demonstrated through foodborne-pathogen-inactivation experiments that due to the targeted and precise delivery, and synergistic effects of AI and ROS incorporated in the iEWNS structure, a pico-to nanogram-level dose of the AI delivered to the surface using this nano-carrier platform is capable of achieving 5-log reductions in minutes of exposure time. This aerosol-based, yet ‘dry’ intervention approach using iEWNS nano-carrier platform offers advantages over current ‘wet’ techniques that are prevalent commercially, which require grams of the AI to achieve similar inactivation, leading to increased chemical risks and chemical waste byproducts. Such a targeted nano-carrier approach has the potential to revolutionize the delivery of antimicrobials for sterilization in the food industry." @default.
- W2893984985 created "2018-10-05" @default.
- W2893984985 creator A5000322162 @default.
- W2893984985 creator A5004193172 @default.
- W2893984985 creator A5007427791 @default.
- W2893984985 creator A5038622222 @default.
- W2893984985 creator A5043191391 @default.
- W2893984985 creator A5051527014 @default.
- W2893984985 creator A5057017311 @default.
- W2893984985 creator A5063529871 @default.
- W2893984985 creator A5067193363 @default.
- W2893984985 creator A5074117382 @default.
- W2893984985 date "2019-02-01" @default.
- W2893984985 modified "2023-10-14" @default.
- W2893984985 title "A nano-carrier platform for the targeted delivery of nature-inspired antimicrobials using Engineered Water Nanostructures for food safety applications" @default.
- W2893984985 cites W1509568685 @default.
- W2893984985 cites W1514534747 @default.
- W2893984985 cites W1583991429 @default.
- W2893984985 cites W1604220382 @default.
- W2893984985 cites W1645236169 @default.
- W2893984985 cites W168457742 @default.
- W2893984985 cites W1888930681 @default.
- W2893984985 cites W1963731846 @default.
- W2893984985 cites W1966191587 @default.
- W2893984985 cites W1978464657 @default.
- W2893984985 cites W1978695076 @default.
- W2893984985 cites W1979609740 @default.
- W2893984985 cites W1981506486 @default.
- W2893984985 cites W1982700031 @default.
- W2893984985 cites W1988830378 @default.
- W2893984985 cites W1993538511 @default.
- W2893984985 cites W1993950777 @default.
- W2893984985 cites W2003161165 @default.
- W2893984985 cites W2009958481 @default.
- W2893984985 cites W2016059941 @default.
- W2893984985 cites W2023334414 @default.
- W2893984985 cites W2023899641 @default.
- W2893984985 cites W2045585303 @default.
- W2893984985 cites W2055909393 @default.
- W2893984985 cites W2058813396 @default.
- W2893984985 cites W2063099726 @default.
- W2893984985 cites W2081416479 @default.
- W2893984985 cites W2081950126 @default.
- W2893984985 cites W2086234811 @default.
- W2893984985 cites W2092099375 @default.
- W2893984985 cites W2103606174 @default.
- W2893984985 cites W2111348049 @default.
- W2893984985 cites W2115351859 @default.
- W2893984985 cites W2117173363 @default.
- W2893984985 cites W2119638146 @default.
- W2893984985 cites W2119802815 @default.
- W2893984985 cites W2121302602 @default.
- W2893984985 cites W2122552877 @default.
- W2893984985 cites W2123218404 @default.
- W2893984985 cites W2127029141 @default.
- W2893984985 cites W2134264935 @default.
- W2893984985 cites W2143150223 @default.
- W2893984985 cites W2150755172 @default.
- W2893984985 cites W2152250563 @default.
- W2893984985 cites W2159353270 @default.
- W2893984985 cites W2163462433 @default.
- W2893984985 cites W2169101231 @default.
- W2893984985 cites W2169848595 @default.
- W2893984985 cites W2174950999 @default.
- W2893984985 cites W2189116376 @default.
- W2893984985 cites W2274007157 @default.
- W2893984985 cites W2275000779 @default.
- W2893984985 cites W2278067661 @default.
- W2893984985 cites W2285455729 @default.
- W2893984985 cites W2314322129 @default.
- W2893984985 cites W2320001517 @default.
- W2893984985 cites W2333412582 @default.
- W2893984985 cites W2496123608 @default.
- W2893984985 cites W2530784765 @default.
- W2893984985 cites W2557622331 @default.
- W2893984985 cites W2562380681 @default.
- W2893984985 cites W2587437657 @default.
- W2893984985 cites W2744094347 @default.
- W2893984985 cites W2757293645 @default.
- W2893984985 cites W2757409587 @default.
- W2893984985 cites W2762858448 @default.
- W2893984985 cites W2810366966 @default.
- W2893984985 cites W2811313862 @default.
- W2893984985 doi "https://doi.org/10.1016/j.foodcont.2018.09.037" @default.
- W2893984985 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7055713" @default.
- W2893984985 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32132770" @default.
- W2893984985 hasPublicationYear "2019" @default.
- W2893984985 type Work @default.
- W2893984985 sameAs 2893984985 @default.
- W2893984985 citedByCount "34" @default.
- W2893984985 countsByYear W28939849852019 @default.
- W2893984985 countsByYear W28939849852020 @default.
- W2893984985 countsByYear W28939849852021 @default.
- W2893984985 countsByYear W28939849852022 @default.
- W2893984985 countsByYear W28939849852023 @default.
- W2893984985 crossrefType "journal-article" @default.
- W2893984985 hasAuthorship W2893984985A5000322162 @default.
- W2893984985 hasAuthorship W2893984985A5004193172 @default.