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• W2894022101 abstract "SUMMARY In primates, both the dorsal anterior cingulate cortex (dACC) and the dorsolateral prefrontal cortex (dlPFC) are key regions of the frontoparietal cognitive control network. To study the role of the dACC and its communication with the dlPFC in cognitive control, we recorded the local field potentials from the dlPFC before and during the reversible deactivation of the dACC, in macaque monkeys engaging in uncued switches between two stimulus-response rules. Cryogenic dACC deactivation impaired response accuracy during rule-maintenance, but not rule-switching, which coincided with a reduction in the correct-error difference in dlPFC beta activities specifically during maintenance of the more challenging rule. During both rule switching and maintenance, dACC deactivation prolonged the animals’ reaction time and reduced task-related theta/alpha activities in the dlPFC; it also weakened dlPFC theta-gamma phase-amplitude modulation. Thus, the dACC and its interaction with the dlPFC plays a critical role in the maintenance of a new, challenging rule." @default.
• W2894022101 created "2018-10-05" @default.
• W2894022101 creator A5038046503 @default.
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• W2894022101 date "2018-09-25" @default.
• W2894022101 modified "2023-09-23" @default.
• W2894022101 title "Macaque anterior cingulate cortex deactivation impairs performance and alters lateral prefrontal oscillatory activities in a rule-switching task" @default.
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• W2894022101 doi "https://doi.org/10.1101/427302" @default.
• W2894022101 hasPublicationYear "2018" @default.
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