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- W2894024435 abstract "Introduction: A one-pot approach for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones in the reaction between 2-aminobezamide and aromatic aldehydes in the presence of highly available carboxylic acids such as benzilic acid, phthalic acid and salicylic acid has been reported. Material and Methods: Carboxylic acids such as benzilic acid, phthalic acid and salicylic acid, used as efficient catalysts for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones, are structurally stable compounds. Synthesized compounds were characterized by 1H NMR and IR spectroscopy and their melting points are in good agreement with previous reports. Results: Results show that carboxylic acids such as benzilic acid, phthalic acid and salicylic can act as effective catalysts in the synthesis of 2,3-dihydroquinazolin-4(1H)-ones without any side products in acceptable reaction time. Conclusion: In conclusion, we use a simple one-pot process for the synthesis of 2,3- dihydroquinazolin-4(1H)-ones by using carboxylic acids which has some advantages such as low cost, nontoxic solvents and simple separation of products. Keywords: Aromatic aldehydes, 2-aminobenzamide, carboxylic acids, 2, 3-dihydroquinazolin-4(1H)-one derivatives, benzilic acid, salicylic acid." @default.
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- W2894024435 date "2018-12-10" @default.
- W2894024435 modified "2023-10-16" @default.
- W2894024435 title "Synthesis of 2,3-Dihydroquinazolin-4(1H)-ones Using Carboxylic Acids as Catalyst" @default.
- W2894024435 doi "https://doi.org/10.2174/2211544707666180924125826" @default.
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