FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894028670> ?p ?o ?g. }

• W2894028670 endingPage "324" @default.
• W2894028670 startingPage "317" @default.
• W2894028670 abstract "The immune regulatory properties of IL-33 have indicated that this cytokine has the capacity to target several immune cells under a variety of immunological responses, including overt inflammation and tolerance. Due to its versatile mechanistics, we sought to investigate the role of IL-33 on mesenchymal stem cells (MSC), a population of cells with recognizable modulatory functions. Our data indicates that IL-33 does not affect the expression of classical MSC markers such as CD29, CD44 and CD73, or the lack of CD45, CD11b and CD117. Also, we found that IL-33 greatly induces iNOS expression and stimulates the secretion of TGF-β and IL-6. Next, we decided to test IFN-γ/IL-33-treated MSC using a skin transplantation model. Our data indicate that allogeneic skin-grafted animals treated with IFN-γ/IL-33-modulated MSC reject as controls. Complementing this finding, we observed that ex vivo re-stimulated draining lymph nodes (dLN) cells from these mice secrete lower amounts of IFN-γ and a slightly higher amount of IL-17. Beside a reduction in CD4+ and CD8+ T cells number, we preliminarily found an increment in the frequencies of CD4+Foxp3+IL-17+ T cells. Altogether, our data propose that IL-33 and IFN-γ modulate MSC phenotype and function, most likely targeting Th1/Th17 axis." @default.
• W2894028670 created "2018-10-05" @default.
• W2894028670 creator A5027565310 @default.
• W2894028670 creator A5088006788 @default.
• W2894028670 creator A5088962834 @default.
• W2894028670 date "2018-11-01" @default.
• W2894028670 modified "2023-10-16" @default.
• W2894028670 title "IFN-γ and IL-33 modulate mesenchymal stem cells function targeting Th1/Th17 axis in a murine skin transplantation model" @default.
• W2894028670 cites W1516197123 @default.
• W2894028670 cites W1525038826 @default.
• W2894028670 cites W1534834493 @default.
• W2894028670 cites W1558361583 @default.
• W2894028670 cites W1663740629 @default.
• W2894028670 cites W1968955229 @default.
• W2894028670 cites W1987348882 @default.
• W2894028670 cites W1995286643 @default.
• W2894028670 cites W2000115558 @default.
• W2894028670 cites W2004490702 @default.
• W2894028670 cites W2013953689 @default.
• W2894028670 cites W2022915249 @default.
• W2894028670 cites W2024326908 @default.
• W2894028670 cites W2025294489 @default.
• W2894028670 cites W2025371271 @default.
• W2894028670 cites W2038399651 @default.
• W2894028670 cites W2056650370 @default.
• W2894028670 cites W2061915520 @default.
• W2894028670 cites W2080236371 @default.
• W2894028670 cites W2085832445 @default.
• W2894028670 cites W2122174032 @default.
• W2894028670 cites W2123166427 @default.
• W2894028670 cites W2155779547 @default.
• W2894028670 cites W2157710399 @default.
• W2894028670 cites W2161497340 @default.
• W2894028670 cites W2163984243 @default.
• W2894028670 cites W2164396254 @default.
• W2894028670 cites W2166662002 @default.
• W2894028670 cites W2167297937 @default.
• W2894028670 cites W2167992899 @default.
• W2894028670 cites W2321485514 @default.
• W2894028670 cites W2776663677 @default.
• W2894028670 doi "https://doi.org/10.1016/j.cyto.2018.09.013" @default.
• W2894028670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30269028" @default.
• W2894028670 hasPublicationYear "2018" @default.
• W2894028670 type Work @default.
• W2894028670 sameAs 2894028670 @default.
• W2894028670 citedByCount "4" @default.
• W2894028670 countsByYear W28940286702020 @default.
• W2894028670 countsByYear W28940286702021 @default.
• W2894028670 countsByYear W28940286702022 @default.
• W2894028670 countsByYear W28940286702023 @default.
• W2894028670 crossrefType "journal-article" @default.
• W2894028670 hasAuthorship W2894028670A5027565310 @default.
• W2894028670 hasAuthorship W2894028670A5088006788 @default.
• W2894028670 hasAuthorship W2894028670A5088962834 @default.
• W2894028670 hasConcept C126322002 @default.
• W2894028670 hasConcept C167672396 @default.
• W2894028670 hasConcept C187316574 @default.
• W2894028670 hasConcept C198826908 @default.
• W2894028670 hasConcept C202751555 @default.
• W2894028670 hasConcept C203014093 @default.
• W2894028670 hasConcept C2776090121 @default.
• W2894028670 hasConcept C2778690821 @default.
• W2894028670 hasConcept C2778740727 @default.
• W2894028670 hasConcept C2779727006 @default.
• W2894028670 hasConcept C2780932548 @default.
• W2894028670 hasConcept C28328180 @default.
• W2894028670 hasConcept C2908647359 @default.
• W2894028670 hasConcept C2911091166 @default.
• W2894028670 hasConcept C502942594 @default.
• W2894028670 hasConcept C55493867 @default.
• W2894028670 hasConcept C71924100 @default.
• W2894028670 hasConcept C79484868 @default.
• W2894028670 hasConcept C86803240 @default.
• W2894028670 hasConcept C8891405 @default.
• W2894028670 hasConcept C95444343 @default.
• W2894028670 hasConcept C99454951 @default.
• W2894028670 hasConceptScore W2894028670C126322002 @default.
• W2894028670 hasConceptScore W2894028670C167672396 @default.
• W2894028670 hasConceptScore W2894028670C187316574 @default.
• W2894028670 hasConceptScore W2894028670C198826908 @default.
• W2894028670 hasConceptScore W2894028670C202751555 @default.
• W2894028670 hasConceptScore W2894028670C203014093 @default.
• W2894028670 hasConceptScore W2894028670C2776090121 @default.
• W2894028670 hasConceptScore W2894028670C2778690821 @default.
• W2894028670 hasConceptScore W2894028670C2778740727 @default.
• W2894028670 hasConceptScore W2894028670C2779727006 @default.
• W2894028670 hasConceptScore W2894028670C2780932548 @default.
• W2894028670 hasConceptScore W2894028670C28328180 @default.
• W2894028670 hasConceptScore W2894028670C2908647359 @default.
• W2894028670 hasConceptScore W2894028670C2911091166 @default.
• W2894028670 hasConceptScore W2894028670C502942594 @default.
• W2894028670 hasConceptScore W2894028670C55493867 @default.
• W2894028670 hasConceptScore W2894028670C71924100 @default.
• W2894028670 hasConceptScore W2894028670C79484868 @default.
• W2894028670 hasConceptScore W2894028670C86803240 @default.
• W2894028670 hasConceptScore W2894028670C8891405 @default.
• W2894028670 hasConceptScore W2894028670C95444343 @default.
• W2894028670 hasConceptScore W2894028670C99454951 @default.

• next