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- W2894045746 abstract "Abstract An important option for identifying and validating key drug targets is the analysis of data from human studies pointing to targets other than the one for which a particular drug has been developed. As is shown in this chapter, this approach is a particularly powerful component in the toolbox for target identification or validation, as those targets are human ones and thus validated in the best test system possible: the human body. This approach is also termed reverse pharmacology or reverse transcription and covers results derived from the use of both small organic molecules and natural compounds contained in traditional (“herbal”) medicines. More details on reverse translation starting from human data are given in this chapter." @default.
- W2894045746 created "2018-10-05" @default.
- W2894045746 creator A5045146149 @default.
- W2894045746 date "2015-01-01" @default.
- W2894045746 modified "2023-09-26" @default.
- W2894045746 title "Human Studies as a Source of Target Information" @default.
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- W2894045746 doi "https://doi.org/10.1016/b978-0-12-800687-0.00010-4" @default.
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