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- W2894053537 abstract "Micelles are self-assembled aggregates of amphiphilic surfactant molecules that are important in a variety of applications, including drug delivery, detergency, and catalysis. It is known that the micellization process is driven by the same physiochemical forces that drive protein folding, aggregation, and biological membrane self-assembly. Nevertheless, the molecular details of how micelle stability changes in water at low temperature are not fully clear. We develop and use a coarse-grained model to investigate how the interplay between nonionic surfactants and the surrounding water at the nanoscale affects the stability of micelles at high and low temperatures. Simulations of preformed C12E5 micelles in explicit water at a range of temperatures reveal the existence of two distinct surfactant conformations within the micelle, a bent structure and an extended structure, the latter being more prevalent at low temperature. Favorable interactions of the surfactant with more ordered solvation water stabilizes the extended configuration, allowing nanoscale wetting of the dry, hydrophobic core of the micelle, leading to the micelle breaking. Taken together, our coarse-grained simulations unravel how energetic and structural changes of the surfactant and the surrounding water destabilize micelles at low temperature, which is a direct consequence of the weakened hydrophobicity. Our approach thus provides an effective mean for extracting the molecular-level changes during hydrophobicity-driven destabilization of molecular self-assembly, which is important in a wide range of fields, including biology, polymer science, and nanotechnology." @default.
- W2894053537 created "2018-10-05" @default.
- W2894053537 creator A5057459575 @default.
- W2894053537 creator A5064335115 @default.
- W2894053537 creator A5071965237 @default.
- W2894053537 creator A5079168252 @default.
- W2894053537 date "2018-09-24" @default.
- W2894053537 modified "2023-09-23" @default.
- W2894053537 title "How Hydrophobic Hydration Destabilizes Surfactant Micelles at Low Temperature: A Coarse-Grained Simulation Study" @default.
- W2894053537 cites W1537479324 @default.
- W2894053537 cites W1574708894 @default.
- W2894053537 cites W1964694986 @default.
- W2894053537 cites W1965095891 @default.
- W2894053537 cites W1966078827 @default.
- W2894053537 cites W1966112322 @default.
- W2894053537 cites W1967235303 @default.
- W2894053537 cites W1970950588 @default.
- W2894053537 cites W1973719554 @default.
- W2894053537 cites W1977475130 @default.
- W2894053537 cites W1981021420 @default.
- W2894053537 cites W1991794210 @default.
- W2894053537 cites W1992019748 @default.
- W2894053537 cites W2003458820 @default.
- W2894053537 cites W2003713109 @default.
- W2894053537 cites W2009884040 @default.
- W2894053537 cites W2010493328 @default.
- W2894053537 cites W2014397914 @default.
- W2894053537 cites W2015156141 @default.
- W2894053537 cites W2017196167 @default.
- W2894053537 cites W2019155195 @default.
- W2894053537 cites W2019465613 @default.
- W2894053537 cites W2021736649 @default.
- W2894053537 cites W2025561938 @default.
- W2894053537 cites W2029667189 @default.
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- W2894053537 cites W2037782625 @default.
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- W2894053537 cites W2045005846 @default.
- W2894053537 cites W2045432121 @default.
- W2894053537 cites W2048441674 @default.
- W2894053537 cites W2049475242 @default.
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- W2894053537 cites W2056668397 @default.
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- W2894053537 cites W2059560778 @default.
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- W2894053537 cites W2061042170 @default.
- W2894053537 cites W2066264050 @default.
- W2894053537 cites W2069986969 @default.
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- W2894053537 cites W2075334481 @default.
- W2894053537 cites W2076679571 @default.
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- W2894053537 cites W2163206218 @default.
- W2894053537 cites W2164763833 @default.
- W2894053537 cites W2171268876 @default.
- W2894053537 cites W2267403502 @default.
- W2894053537 cites W2267919102 @default.
- W2894053537 cites W2314172351 @default.
- W2894053537 cites W2320754367 @default.
- W2894053537 cites W2323132072 @default.
- W2894053537 cites W2323178299 @default.
- W2894053537 cites W2338395607 @default.
- W2894053537 cites W2343474522 @default.
- W2894053537 cites W2409322723 @default.
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- W2894053537 cites W2594767224 @default.
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- W2894053537 doi "https://doi.org/10.1021/acs.langmuir.8b01994" @default.
- W2894053537 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30247911" @default.
- W2894053537 hasPublicationYear "2018" @default.
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