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• W2894072089 abstract "Accumulating evidence suggests a relationship between problematic hypersexual behavior (PHB) and diminished executive control. Clinical studies have demonstrated that individuals with PHB exhibit high levels of impulsivity; however, relatively little is known regarding the neural mechanisms underlying impaired executive control in PHB. This study investigated the neural correlates of executive control in individuals with PHB and healthy controls using event-related functional magnetic resonance imaging (fMRI). Twenty-three individuals with PHB and 22 healthy control participants underwent fMRI while performing a Stroop task. Response time and error rates were measured as surrogate indicators of executive control. Individuals with PHB exhibited impaired task performance and lower activation in the right dorsolateral prefrontal cortex (DLPFC) and inferior parietal cortex relative to healthy controls during the Stroop task. In addition, blood oxygen level-dependent responses in these areas were negatively associated with PHB severity. The right DLPFC and inferior parietal cortex are associated with higher-order cognitive control and visual attention, respectively. Our findings suggest that individuals with PHB have diminished executive control and impaired functionality in the right DLPFC and inferior parietal cortex, providing a neural basis for PHB." @default.
• W2894072089 created "2018-10-05" @default.
• W2894072089 creator A5009054709 @default.
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• W2894072089 date "2018-09-25" @default.
• W2894072089 modified "2023-09-26" @default.
• W2894072089 title "Altered Prefrontal and Inferior Parietal Activity During a Stroop Task in Individuals With Problematic Hypersexual Behavior" @default.
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• W2894072089 doi "https://doi.org/10.3389/fpsyt.2018.00460" @default.
• W2894072089 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6167473" @default.
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