Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894072351> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2894072351 abstract "The Deepwater Horizon oil spill released millions of barrels of oil into the Gulf of Mexico, impacting economically and ecologically important fishes. Polycyclic aromatic hydrocarbons (PAHs) present in the oil have been shown to cause developmental impairments in early life stage fishes, such as morphological and behavioral changes related to eye formation and visual processing following PAH exposure. Prior research reported reduced eye growth in open water, pelagic species, as well as reduced photoreceptor-specific transcription factors associated with eye development following exposure to crude oil. Though changes in transcriptomic-level pathways associated with vision and visual processing have been reported, it has yet to be determined how these changes relate to physiological or behavioral-level effects in fish. Therefore, the present studies evaluated the effect of weathered crude oil on eye development and visual function in mahi-mahi, red drum, sheepshead minnow, and zebrafish larvae. Fish were assessed through several visually-mediated behavioral assays, analyzed histologically and immunohistologically, along with subsequent transcriptomic analyses and associated gene expression changes. Larvae exposed to crude oil experienced significantly reduced abilities to exhibit optomotor or optokinetic responses relative to controls, with associated reductions in retinal development. Furthermore, genes associated with eye development and phototransduction were downregulated, with subsequent decreases in the immunofluorescence of neurological connections within the retina and a choroid-specific increase in apoptotic activity. We related oil-induced transcriptomic-level effects to morphological, physiological, and behavioral-level impairments in larval teleost fishes." @default.
- W2894072351 created "2018-10-05" @default.
- W2894072351 creator A5084881168 @default.
- W2894072351 date "2018-08-01" @default.
- W2894072351 modified "2023-09-24" @default.
- W2894072351 title "Effects of Deepwater Horizon Crude Oil on Visual Function in Teleost Fishes" @default.
- W2894072351 hasPublicationYear "2018" @default.
- W2894072351 type Work @default.
- W2894072351 sameAs 2894072351 @default.
- W2894072351 citedByCount "0" @default.
- W2894072351 crossrefType "dissertation" @default.
- W2894072351 hasAuthorship W2894072351A5084881168 @default.
- W2894072351 hasConcept C104317684 @default.
- W2894072351 hasConcept C127413603 @default.
- W2894072351 hasConcept C131667965 @default.
- W2894072351 hasConcept C150194340 @default.
- W2894072351 hasConcept C162317418 @default.
- W2894072351 hasConcept C169760540 @default.
- W2894072351 hasConcept C173758957 @default.
- W2894072351 hasConcept C18903297 @default.
- W2894072351 hasConcept C19269858 @default.
- W2894072351 hasConcept C2776878037 @default.
- W2894072351 hasConcept C2777093970 @default.
- W2894072351 hasConcept C2987168347 @default.
- W2894072351 hasConcept C505870484 @default.
- W2894072351 hasConcept C55493867 @default.
- W2894072351 hasConcept C77942228 @default.
- W2894072351 hasConcept C78762247 @default.
- W2894072351 hasConcept C86803240 @default.
- W2894072351 hasConcept C90856448 @default.
- W2894072351 hasConceptScore W2894072351C104317684 @default.
- W2894072351 hasConceptScore W2894072351C127413603 @default.
- W2894072351 hasConceptScore W2894072351C131667965 @default.
- W2894072351 hasConceptScore W2894072351C150194340 @default.
- W2894072351 hasConceptScore W2894072351C162317418 @default.
- W2894072351 hasConceptScore W2894072351C169760540 @default.
- W2894072351 hasConceptScore W2894072351C173758957 @default.
- W2894072351 hasConceptScore W2894072351C18903297 @default.
- W2894072351 hasConceptScore W2894072351C19269858 @default.
- W2894072351 hasConceptScore W2894072351C2776878037 @default.
- W2894072351 hasConceptScore W2894072351C2777093970 @default.
- W2894072351 hasConceptScore W2894072351C2987168347 @default.
- W2894072351 hasConceptScore W2894072351C505870484 @default.
- W2894072351 hasConceptScore W2894072351C55493867 @default.
- W2894072351 hasConceptScore W2894072351C77942228 @default.
- W2894072351 hasConceptScore W2894072351C78762247 @default.
- W2894072351 hasConceptScore W2894072351C86803240 @default.
- W2894072351 hasConceptScore W2894072351C90856448 @default.
- W2894072351 hasLocation W28940723511 @default.
- W2894072351 hasOpenAccess W2894072351 @default.
- W2894072351 hasPrimaryLocation W28940723511 @default.
- W2894072351 hasRelatedWork W1990424153 @default.
- W2894072351 hasRelatedWork W2138565989 @default.
- W2894072351 hasRelatedWork W2190928574 @default.
- W2894072351 hasRelatedWork W2330689064 @default.
- W2894072351 hasRelatedWork W267788780 @default.
- W2894072351 hasRelatedWork W3092795513 @default.
- W2894072351 hasRelatedWork W3186102591 @default.
- W2894072351 hasRelatedWork W3189547045 @default.
- W2894072351 isParatext "false" @default.
- W2894072351 isRetracted "false" @default.
- W2894072351 magId "2894072351" @default.
- W2894072351 workType "dissertation" @default.