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- W2894077287 abstract "Abstract The relationship between type-1 diabetes mellitus (DM) and cochlear dysfunction remains inconclusive. The purpose of this study was to examine otoacoustic emissions (OAEs) in normal-hearing young adults with type-1 DM as compared with matched controls and identify potential covariates influencing OAE findings. Cross-sectional study. N = 40 young adults aged 18–28 years including individuals with type-1 DM (n = 20) and age–gender matched controls (n = 20) with normal hearing sensitivity. Measures of pure-tone threshold sensitivity and OAEs, including distortion product otoacoustic emissions (DPOAEs), transient evoked OAEs, and DPOAE fine structure, were compared between groups. Covariates such as noise exposure and DM-related factors (e.g., duration of disease, glycated hemoglobin levels) were considered. Statistical analysis included analysis of variance and linear regression. Measures of hearing sensitivity and auditory function in both groups were comparable for all assays, except DPOAE fine structure. A reduced number of fine structure peaks and component amplitudes were found in the type-1 diabetes DM group with the primary difference in the reflection component. The results indicate that reduced cochlear function in young adults with type-1 DM can be revealed using DPOAE fine structure, suggesting potential clinical applications of DPOAE fine structure in early identification of cochlear pathology. Potential factors underlying these findings are discussed." @default.
- W2894077287 created "2018-10-05" @default.
- W2894077287 creator A5042376161 @default.
- W2894077287 creator A5061419437 @default.
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- W2894077287 date "2019-06-01" @default.
- W2894077287 modified "2023-09-26" @default.
- W2894077287 title "Early Indices of Reduced Cochlear Function in Young Adults with Type-1 Diabetes Revealed by DPOAE Fine Structure" @default.
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- W2894077287 doi "https://doi.org/10.3766/jaaa.17113" @default.
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