FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894186025> ?p ?o ?g. }

• W2894186025 abstract "Background: Motor learning is impaired in Parkinson's disease (PD), with patients demonstrating deficits in skill acquisition (online learning) and consolidation (offline learning) compared to healthy adults of similar age. Recent studies in young adults suggest that single bouts of aerobic exercise (AEX), performed in close temporal proximity to practicing a new motor task, may facilitate motor skill learning. Thus, we aimed at investigating the effects of a single bout of aerobic cycling on online and offline learning in PD patients. Methods: 17 PD patients (Hoehn and Yahr 1 - 2.5, age: 64.4 ± 6.2) participated in this crossover study. Immediately prior to practicing a novel balance task, patients either performed 30 min of (i) moderate intensity (60-70% VO2max) aerobic cycling, or (ii) seated rest (order counterbalanced). The task required patients to stabilize a balance platform (stabilometer) in a horizontal position for 30 s. For each experimental condition, patients performed 15 acquisition trials, followed by a retention test 24 h later. We calculated time in balance (platform within ± 5° from horizontal) for each trial, and analyzed within- and between-subjects differences in skill acquisition (online learning) and skill retention (offline learning) using mixed repeated-measures ANOVA. Results: We found that the exercise bout had no effect on performance level or online gains during acquisition, despite affecting the time course of skill improvements (larger initial and reduced late skill gains). Aerobic cycling significantly improved offline learning, as reflected by larger 24-h skill retention compared to the rest condition. Conclusion: Our results suggest that a single bout of moderate-intensity AEX is effective in improving motor skill consolidation in PD patients. Thus, acute exercise may represent an effective strategy to enhance motor memory formation in this population. More work is necessary to understand the underlying mechanisms, the optimal scheduling of exercise, and the applicability to other motor tasks. Further, the potential for patients in later disease stages need to be investigated. The study was a priori registered at ClinicalTrials.gov (NCT03245216)." @default.
• W2894186025 created "2018-10-05" @default.
• W2894186025 creator A5010388856 @default.
• W2894186025 creator A5026639768 @default.
• W2894186025 creator A5041953637 @default.
• W2894186025 creator A5066832631 @default.
• W2894186025 creator A5072540951 @default.
• W2894186025 creator A5091615813 @default.
• W2894186025 date "2018-10-22" @default.
• W2894186025 modified "2023-09-26" @default.
• W2894186025 title "A Single Bout of Aerobic Exercise Improves Motor Skill Consolidation in Parkinson’s Disease" @default.
• W2894186025 cites W1098325473 @default.
• W2894186025 cites W1118443095 @default.
• W2894186025 cites W1470674207 @default.
• W2894186025 cites W1917007748 @default.
• W2894186025 cites W1963663193 @default.
• W2894186025 cites W1969725360 @default.
• W2894186025 cites W197066864 @default.
• W2894186025 cites W1978596048 @default.
• W2894186025 cites W1978645641 @default.
• W2894186025 cites W1984402203 @default.
• W2894186025 cites W1985098575 @default.
• W2894186025 cites W1988491410 @default.
• W2894186025 cites W1994208622 @default.
• W2894186025 cites W1994341217 @default.
• W2894186025 cites W1994459030 @default.
• W2894186025 cites W1999151911 @default.
• W2894186025 cites W2005560709 @default.
• W2894186025 cites W2007108464 @default.
• W2894186025 cites W2007207130 @default.
• W2894186025 cites W2017144522 @default.
• W2894186025 cites W2019256317 @default.
• W2894186025 cites W2021515441 @default.
• W2894186025 cites W2022056324 @default.
• W2894186025 cites W2038601986 @default.
• W2894186025 cites W2040943812 @default.
• W2894186025 cites W2047262956 @default.
• W2894186025 cites W2052069076 @default.
• W2894186025 cites W2057965539 @default.
• W2894186025 cites W2063891861 @default.
• W2894186025 cites W2066977609 @default.
• W2894186025 cites W2068606962 @default.
• W2894186025 cites W2071256705 @default.
• W2894186025 cites W2076359113 @default.
• W2894186025 cites W2077073169 @default.
• W2894186025 cites W2079707802 @default.
• W2894186025 cites W2084886790 @default.
• W2894186025 cites W2088476185 @default.
• W2894186025 cites W2091646494 @default.
• W2894186025 cites W2107718763 @default.
• W2894186025 cites W2109538913 @default.
• W2894186025 cites W2117641008 @default.
• W2894186025 cites W2120387239 @default.
• W2894186025 cites W2120708642 @default.
• W2894186025 cites W2121552348 @default.
• W2894186025 cites W2121956288 @default.
• W2894186025 cites W2124025171 @default.
• W2894186025 cites W2128238934 @default.
• W2894186025 cites W2134562178 @default.
• W2894186025 cites W2134807533 @default.
• W2894186025 cites W2140978740 @default.
• W2894186025 cites W2143978324 @default.
• W2894186025 cites W2145954079 @default.
• W2894186025 cites W2148887520 @default.
• W2894186025 cites W2151905266 @default.
• W2894186025 cites W2154873668 @default.
• W2894186025 cites W2157289187 @default.
• W2894186025 cites W2158937646 @default.
• W2894186025 cites W2170725206 @default.
• W2894186025 cites W2171129594 @default.
• W2894186025 cites W2202400249 @default.
• W2894186025 cites W2227553067 @default.
• W2894186025 cites W2260419993 @default.
• W2894186025 cites W2264299191 @default.
• W2894186025 cites W2285299952 @default.
• W2894186025 cites W2324271821 @default.
• W2894186025 cites W2326874780 @default.
• W2894186025 cites W2462372318 @default.
• W2894186025 cites W2465425574 @default.
• W2894186025 cites W2471934658 @default.
• W2894186025 cites W2519745171 @default.
• W2894186025 cites W2522367374 @default.
• W2894186025 cites W2537305344 @default.
• W2894186025 cites W2557836110 @default.
• W2894186025 cites W2604294741 @default.
• W2894186025 cites W2610037501 @default.
• W2894186025 cites W2733702614 @default.
• W2894186025 cites W2743844174 @default.
• W2894186025 cites W2749718288 @default.
• W2894186025 cites W2755567469 @default.
• W2894186025 cites W2765167702 @default.
• W2894186025 cites W2790184581 @default.
• W2894186025 cites W2792312129 @default.
• W2894186025 cites W2793937129 @default.
• W2894186025 cites W2795202952 @default.
• W2894186025 cites W2802570735 @default.
• W2894186025 cites W2805009962 @default.
• W2894186025 cites W4249500748 @default.
• W2894186025 cites W428860780 @default.
• W2894186025 cites W79059582 @default.

• next