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- W2894348533 abstract "In the course of identifying promissory plants with hypoglycemic and antioxidant activities we evaluated the α-glucosidase and α-amylase inhibitory activities, the total soluble phenolic content (TSPC), the free radicals (DPPH, ABTS) scavenging activity and the linoleic autoxidation inhibitory capacity, of twelve plants used in traditional medicine of Ecuador: Siparuna eggersi (Monte de oso), Croton wagneri(Moshquera), Ilex guayusa (Guayusa), Baccharis genistelloides (Tres filos), Neonelsonia acuminate(Zanahoria blanca), Oreocallis grandiflora (Cucharillo), Verbena litoralis (Verbena), Justicia colorata(Insulina), Artocarpus altilis (Fruto del pan), Adiantun poiretii (Culantrillo), Costus comosus (Cana agria) and Piper crassinervium (Guabiduca).The study has shown that O. grandiflora was superior in comparison to the others plants, especially, in terms of its inhibitory activity on α-glucosidase (IC50 = 2.8 ± 0.4 μg/mL) and α-amylase (IC50 = 161.5 ± 1.3 μg/mL), as well as for free radicals (DPPH, ABTS) scavenging activity (IC50-DPPH = 9.9 ± 0.06 μg/mL; IC50-TEAC = 6.6 ± 0.55 μg/mL). On the other hand, A. altilishad the major linoleic autoxidation inhibitory capacity (IC50-β-CLAMS = 3.1 ± 0.20 μg/mL), and O. grandifloraagain had the highest value of total soluble phenolic content (TSPC = 185.9 ± 0.09 GAEs/g extract). These findings suggest that O. grandiflora might be considered as an alternative enzyme inhibitory and antioxidative agent for the treatment of diabetes mellitus." @default.
- W2894348533 created "2018-10-05" @default.
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- W2894348533 date "2018-06-01" @default.
- W2894348533 modified "2023-10-03" @default.
- W2894348533 title "IN VITRO HYPOGLYCEMIC AND ANTIOXIDANT ACTIVITIES OF SOME MEDICINAL PLANTS USED IN TREATMENT OF DIABETES IN SOUTHERN ECUADOR" @default.
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- W2894348533 doi "https://doi.org/10.26621/xiv18.2018.06.a03.pucesi.2550.6684" @default.
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