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• W2894372119 abstract "Objective To determine correlation between race and receipt of optimal treatment for ovarian cancer and the impact of this on overall survival. Methods Using SEER-linked Medicare database, women 66 and older diagnosed with advanced ovarian cancer between 2002 and 2011 were identified. Patients with unclear histology, diagnosed on autopsy and without Medicare Parts A and B were excluded. We used Chi-square test for categorical variables, F test for continuous variables, and multivariable logistic regression to identify characteristics associated with receipt of surgery and chemotherapy. Kaplan–Meier analysis was used to compare overall survival rates. Cox Proportional Hazards regression was performed to identify factors associated with 5-year survival. Results 9016 ovarian cancer patients were included. 2638 had primary chemotherapy, 4854 had primary surgery, and 1524 had no treatment. 7653 (84.9%) were white, 572 (6.3%) black, 479 (5.3%) Hispanic, and 312 (3.5%) were of other race/ethnicity. More white patients (57.2%) received both chemotherapy and surgery compared to black (39.9%), Hispanic (48.9%), or other (54.2%) (p < .001). Receipt of either only surgery or chemotherapy, or receipt of neither, resulted in higher risk of death when compared to receipt of both. On multivariable analysis, black (OR 0.58 [0.46–0.73]) and Hispanic (0.69 [0.54–0.88]) patients were less likely to receive both chemotherapy and surgery. Being of black race was significantly correlated with worse overall survival [HR 1.13 (1.03–1.23); p = .02]. Conclusions Non-white women are less likely to receive the standard of care treatment for ovarian cancer and more likely to die from their disease than white women." @default.
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• W2894372119 date "2018-11-01" @default.
• W2894372119 modified "2023-10-03" @default.
• W2894372119 title "Disparities in treatment and survival among elderly ovarian cancer patients" @default.
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• W2894372119 doi "https://doi.org/10.1016/j.ygyno.2018.08.041" @default.
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