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- W2894436064 abstract "32歳女性.9歳時にミオクローヌスと全般強直間代発作が出現し,遺伝子検査でUnverricht-Lundborg病と診断された.内服により全般強直間代発作は抑制されたが,ミオクローヌスは治療抵抗性であり認知機能障害,構音障害,ミオクローヌス,協調運動障害,高度の起立歩行障害と強い歩行恐怖症がみられた.ペランパネルを1 mg/日から漸増後,2 mg/日でミオクローヌスは著明に改善し,歩行恐怖症も軽減した.また体性感覚誘発電位の振幅も低下し,一次運動感覚野の過剰興奮の減弱が示唆された.ペランパネルは皮質ミオクローヌス,起立歩行障害と歩行恐怖症に有効な治療と考えられた." @default.
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- W2894436064 date "2018-01-01" @default.
- W2894436064 modified "2023-09-29" @default.
- W2894436064 title "Low-dose perampanel improved cortical myoclonus and basophobia in a patient with Unverricht-Lundborg disease: a case report" @default.
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- W2894436064 doi "https://doi.org/10.5692/clinicalneurol.cn-001179" @default.
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