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- W2894466260 abstract "Nontypeable Haemophilus influenzae (NT Hi ) is an extremely common human pathobiont that persists on the airway mucosal surface within biofilm communities, and our previous work has shown that NT Hi biofilm maturation is coordinated by the production and uptake of autoinducer 2 (AI-2) quorum signals. To directly test roles for AI-2 in maturation and maintenance of NT Hi biofilms, we generated an NT Hi 86-028NP mutant in which luxS transcription was under the control of the xylA promoter (NT Hi 86-028NP luxS xylA :: luxS ), rendering AI-2 production inducible by xylose." @default.
- W2894466260 created "2018-10-05" @default.
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- W2894466260 date "2018-12-01" @default.
- W2894466260 modified "2023-10-16" @default.
- W2894466260 title "Autoinducer 2 (AI-2) Production by Nontypeable Haemophilus influenzae 86-028NP Promotes Expression of a Predicted Glycosyltransferase That Is a Determinant of Biofilm Maturation, Prevention of Dispersal, and Persistence In Vivo" @default.
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- W2894466260 doi "https://doi.org/10.1128/iai.00506-18" @default.
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