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• W2894477269 abstract "Morphogen signalling represents a key mechanism of developmental processes during animal development. Previously, several evolutionary conserved morphogen signalling pathways have been identified, and their players such as the morphogen receptors, morphogen modulating factors (MMFs) and the morphogens themselves have been studied. MMFs are factors that regulate morphogen distribution and activity. The interactions of MMFs with different morphogen signalling pathways such as Wnt signalling, Hedgehog (Hh) signalling and Decapentaplegic (Dpp) signalling are complex because some of the MMFs have been shown to interact with more than one signalling pathway, and depending on genetic context, to have different, biphasic or even opposing function. This complicates the interpretation of expression data and functional data of MMFs and may be one reason why data on MMFs in other arthropods than Drosophila are scarce or totally lacking. As a first step to a better understanding of the potential roles of MMFs in arthropod development, we investigate here the embryonic expression patterns of division abnormally delayed (dally), dally-like protein (dlp), shifted (shf) and secreted frizzled-related protein 125 (sFRP125) and sFRP34 in the beetle Tribolium castaneum, the spider Parasteatoda tepidariorum, the millipede Glomeris marginata and the onychophoran Euperipatoides kanangrensis. This pioneer study represents the first comprehensive comparative data set of these genes in panarthropods. Expression profiles reveal a high degree of diversity, suggesting that MMFs may represent highly evolvable nodes in otherwise conserved gene regulatory networks. Conserved aspects of MMF expression, however, appear to concern function in segmentation and limb development, two of the key topics of evolutionary developmental research." @default.
• W2894477269 created "2018-10-05" @default.
• W2894477269 creator A5022092533 @default.
• W2894477269 creator A5068768940 @default.
• W2894477269 creator A5090256243 @default.
• W2894477269 date "2018-09-29" @default.
• W2894477269 modified "2023-10-12" @default.
• W2894477269 title "Gene expression analysis of potential morphogen signalling modifying factors in Panarthropoda" @default.
• W2894477269 cites W1433152810 @default.
• W2894477269 cites W1522097300 @default.
• W2894477269 cites W1522864600 @default.
• W2894477269 cites W1587106356 @default.
• W2894477269 cites W1605394511 @default.
• W2894477269 cites W1631692643 @default.
• W2894477269 cites W1648692159 @default.
• W2894477269 cites W1649982107 @default.
• W2894477269 cites W1772672315 @default.
• W2894477269 cites W1869366780 @default.
• W2894477269 cites W1912923276 @default.
• W2894477269 cites W1941585788 @default.
• W2894477269 cites W1964943774 @default.
• W2894477269 cites W1968183193 @default.
• W2894477269 cites W1969375008 @default.
• W2894477269 cites W1969910714 @default.
• W2894477269 cites W1975420952 @default.
• W2894477269 cites W1976416223 @default.
• W2894477269 cites W1976642158 @default.
• W2894477269 cites W1982471296 @default.
• W2894477269 cites W1982709013 @default.
• W2894477269 cites W1989117766 @default.
• W2894477269 cites W1997215160 @default.
• W2894477269 cites W2000646745 @default.
• W2894477269 cites W2000658856 @default.
• W2894477269 cites W2003711957 @default.
• W2894477269 cites W2009474613 @default.
• W2894477269 cites W2012966503 @default.
• W2894477269 cites W2015574037 @default.
• W2894477269 cites W2015892335 @default.
• W2894477269 cites W2028093081 @default.
• W2894477269 cites W2031065774 @default.
• W2894477269 cites W2031569719 @default.
• W2894477269 cites W2031900878 @default.
• W2894477269 cites W2033401579 @default.
• W2894477269 cites W2037956956 @default.
• W2894477269 cites W2038701440 @default.
• W2894477269 cites W2039038180 @default.
• W2894477269 cites W2039075224 @default.
• W2894477269 cites W2039127205 @default.
• W2894477269 cites W2041313345 @default.
• W2894477269 cites W2047659079 @default.
• W2894477269 cites W2049328469 @default.
• W2894477269 cites W2049338893 @default.
• W2894477269 cites W2049829724 @default.
• W2894477269 cites W2053698830 @default.
• W2894477269 cites W2058816652 @default.
• W2894477269 cites W2060520959 @default.
• W2894477269 cites W2065542901 @default.
• W2894477269 cites W2067407780 @default.
• W2894477269 cites W2067669794 @default.
• W2894477269 cites W2068345933 @default.
• W2894477269 cites W2074202963 @default.
• W2894477269 cites W2078402042 @default.
• W2894477269 cites W2079721551 @default.
• W2894477269 cites W2079819294 @default.
• W2894477269 cites W2080032658 @default.
• W2894477269 cites W2080213723 @default.
• W2894477269 cites W2082187555 @default.
• W2894477269 cites W2082676215 @default.
• W2894477269 cites W2095231998 @default.
• W2894477269 cites W2101296021 @default.
• W2894477269 cites W2102638056 @default.
• W2894477269 cites W2108173304 @default.
• W2894477269 cites W2108345995 @default.
• W2894477269 cites W2108731933 @default.
• W2894477269 cites W2112850885 @default.
• W2894477269 cites W2114355711 @default.
• W2894477269 cites W2114716472 @default.
• W2894477269 cites W2114732932 @default.
• W2894477269 cites W2116120836 @default.
• W2894477269 cites W2126292167 @default.
• W2894477269 cites W2133053826 @default.
• W2894477269 cites W2133324080 @default.
• W2894477269 cites W2135914580 @default.
• W2894477269 cites W2136439746 @default.
• W2894477269 cites W2140261464 @default.
• W2894477269 cites W2141890905 @default.
• W2894477269 cites W2152567646 @default.
• W2894477269 cites W2152695624 @default.
• W2894477269 cites W2153261864 @default.
• W2894477269 cites W2161444534 @default.
• W2894477269 cites W2162553565 @default.
• W2894477269 cites W2163569157 @default.
• W2894477269 cites W2165459158 @default.
• W2894477269 cites W2168149321 @default.
• W2894477269 cites W2168151871 @default.
• W2894477269 cites W2168310032 @default.
• W2894477269 cites W2186081087 @default.
• W2894477269 cites W2193844257 @default.
• W2894477269 cites W2344800260 @default.
• W2894477269 cites W2412721446 @default.

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