FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894520001> ?p ?o ?g. }

• W2894520001 endingPage "33" @default.
• W2894520001 startingPage "26" @default.
• W2894520001 abstract "Abstract Objective Sex-specific diagnostic cut-offs may improve the test characteristics of high-sensitivity troponin assays for the diagnosis of myocardial infarction (MI). The objective of this study was to quantify test characteristics of sex-specific cut-offs of a single, high-sensitivity cardiac troponin T (hs-cTnT) assay for 7-day MI in patients with chest pain. Methods This observational cohort study included consecutive emergency department (ED) patients with suspected cardiac chest pain from four Canadian EDs who had an hs-cTnT assay performed within 60 minutes of ED arrival. The primary outcome was MI at 7 days. We quantified test characteristics (sensitivity, negative predictive value [NPV], likelihood ratios and proportion of patients ruled out) for multiple combinations of sex-specific, rule-out cut-offs. We calculated the net reclassification index compared to universal rule-out cut-offs. Results In 7,130 patients (3,931 men and 3,199 women), the 7-day MI incidence was 7.38% among men and 3.78% among women. Optimal sex-specific cut-offs (<8 ng/L for men and <7 ng/L for women) had a 98.5% sensitivity for MI and ruled out MI in 55.8% of patients. This would enable an absolute increase in the proportion of patients who were able to be ruled out with a single hs-cTnT of 13.2% to 22.2%, depending on the universal rule-out concentration used as a comparator. Conclusions Sex-specific hs-cTnT cut-offs for ruling out MI at ED arrival may improve classification performance, enabling more patients to be safely ruled out at ED arrival. However, differences between sex-specific and universal cut-off concentrations are within the variation of the assay, limiting the clinical utility of this approach. These findings should be confirmed in other data sets." @default.
• W2894520001 created "2018-10-05" @default.
• W2894520001 creator A5018596307 @default.
• W2894520001 creator A5033154988 @default.
• W2894520001 creator A5034726343 @default.
• W2894520001 creator A5043771520 @default.
• W2894520001 creator A5044308683 @default.
• W2894520001 creator A5052576941 @default.
• W2894520001 creator A5056246750 @default.
• W2894520001 creator A5066215913 @default.
• W2894520001 creator A5067554975 @default.
• W2894520001 creator A5069307903 @default.
• W2894520001 creator A5069604676 @default.
• W2894520001 creator A5070506894 @default.
• W2894520001 creator A5081088313 @default.
• W2894520001 date "2018-09-28" @default.
• W2894520001 modified "2023-09-26" @default.
• W2894520001 title "Sex-specific, high-sensitivity cardiac troponin T cut-off concentrations for ruling out acute myocardial infarction with a single measurement" @default.
• W2894520001 cites W1496454720 @default.
• W2894520001 cites W1523520019 @default.
• W2894520001 cites W1899121568 @default.
• W2894520001 cites W2000847886 @default.
• W2894520001 cites W2033201465 @default.
• W2894520001 cites W2050034771 @default.
• W2894520001 cites W2103645914 @default.
• W2894520001 cites W2112316706 @default.
• W2894520001 cites W2121236256 @default.
• W2894520001 cites W2137761428 @default.
• W2894520001 cites W2140777879 @default.
• W2894520001 cites W2142598336 @default.
• W2894520001 cites W2171276211 @default.
• W2894520001 cites W2217854679 @default.
• W2894520001 cites W2344757101 @default.
• W2894520001 cites W2419668996 @default.
• W2894520001 cites W2471449643 @default.
• W2894520001 cites W2523601922 @default.
• W2894520001 cites W2558460754 @default.
• W2894520001 cites W2558977345 @default.
• W2894520001 cites W2564611085 @default.
• W2894520001 cites W2610548256 @default.
• W2894520001 cites W2614495315 @default.
• W2894520001 cites W2620298877 @default.
• W2894520001 cites W2782580446 @default.
• W2894520001 cites W4292856638 @default.
• W2894520001 doi "https://doi.org/10.1017/cem.2018.435" @default.
• W2894520001 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30261938" @default.
• W2894520001 hasPublicationYear "2018" @default.
• W2894520001 type Work @default.
• W2894520001 sameAs 2894520001 @default.
• W2894520001 citedByCount "15" @default.
• W2894520001 countsByYear W28945200012019 @default.
• W2894520001 countsByYear W28945200012020 @default.
• W2894520001 countsByYear W28945200012021 @default.
• W2894520001 countsByYear W28945200012022 @default.
• W2894520001 countsByYear W28945200012023 @default.
• W2894520001 crossrefType "journal-article" @default.
• W2894520001 hasAuthorship W2894520001A5018596307 @default.
• W2894520001 hasAuthorship W2894520001A5033154988 @default.
• W2894520001 hasAuthorship W2894520001A5034726343 @default.
• W2894520001 hasAuthorship W2894520001A5043771520 @default.
• W2894520001 hasAuthorship W2894520001A5044308683 @default.
• W2894520001 hasAuthorship W2894520001A5052576941 @default.
• W2894520001 hasAuthorship W2894520001A5056246750 @default.
• W2894520001 hasAuthorship W2894520001A5066215913 @default.
• W2894520001 hasAuthorship W2894520001A5067554975 @default.
• W2894520001 hasAuthorship W2894520001A5069307903 @default.
• W2894520001 hasAuthorship W2894520001A5069604676 @default.
• W2894520001 hasAuthorship W2894520001A5070506894 @default.
• W2894520001 hasAuthorship W2894520001A5081088313 @default.
• W2894520001 hasBestOaLocation W28945200011 @default.
• W2894520001 hasConcept C118552586 @default.
• W2894520001 hasConcept C120665830 @default.
• W2894520001 hasConcept C121332964 @default.
• W2894520001 hasConcept C126322002 @default.
• W2894520001 hasConcept C144469398 @default.
• W2894520001 hasConcept C164705383 @default.
• W2894520001 hasConcept C174446222 @default.
• W2894520001 hasConcept C2778704086 @default.
• W2894520001 hasConcept C2780724011 @default.
• W2894520001 hasConcept C36036425 @default.
• W2894520001 hasConcept C500558357 @default.
• W2894520001 hasConcept C61511704 @default.
• W2894520001 hasConcept C71924100 @default.
• W2894520001 hasConcept C72563966 @default.
• W2894520001 hasConcept C8880881 @default.
• W2894520001 hasConceptScore W2894520001C118552586 @default.
• W2894520001 hasConceptScore W2894520001C120665830 @default.
• W2894520001 hasConceptScore W2894520001C121332964 @default.
• W2894520001 hasConceptScore W2894520001C126322002 @default.
• W2894520001 hasConceptScore W2894520001C144469398 @default.
• W2894520001 hasConceptScore W2894520001C164705383 @default.
• W2894520001 hasConceptScore W2894520001C174446222 @default.
• W2894520001 hasConceptScore W2894520001C2778704086 @default.
• W2894520001 hasConceptScore W2894520001C2780724011 @default.
• W2894520001 hasConceptScore W2894520001C36036425 @default.
• W2894520001 hasConceptScore W2894520001C500558357 @default.
• W2894520001 hasConceptScore W2894520001C61511704 @default.
• W2894520001 hasConceptScore W2894520001C71924100 @default.

• next