FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894522694> ?p ?o ?g. }

• W2894522694 abstract "1. Twenty four carious tooth were collected and screened for the isolation and identification of S.mutans and L.acidophillus.2. The bacteria isolated were investigated for an experimental study of in-vitro antimicrobial photodynamic therapy effect in carious dentin slabs.3. Silver nano particles in a concentration of 100μg/ml wereprepared by borohydride reduction method and examined fordifferent time of contact with the infected dentine.4. The experiment was such that 60 slabs of occlusal human dentin were randomly assigned to six groups, exposed to a light emiting diode laser at 630 nm, and with a photosensitizer TBO-100μg/ml and also tested with Nanosilver particles and the combination of all the above antimicrobial treatments as follows:a. Group I - Negative control,b. Group II- Positive control,c. Group III-LED Laser Treatment,d. Group IV-LED Laser + TBO Dye Treatment.e. Group V -Nanosilver Treatment at different time intervals of 20, 40, 60, 80 seconds f. Group VI-Dye + Nanosilver + LED Treatment.5. The slabs were subjected to a model for caries production with S.mutans and L.acidophilus inoculation in Brain heart infusion BHI broth.6. After a 10 -day period of incubation, samples of carious dentin were collected before and after each treatment and cultured for streptococci mutans and Lactobacillus acidophillus.7. The lighted groups were irradiated with energy density of 48J/cm2 obtained for about 60 seconds respectively.TB-O was applied for 5 minutes.8. The samples of Group V were immersed in nanosilver solution for 20, 40, 60 and 80 seconds respectively and examined for streptococci and lactobacilli counts.9. The data were analyzed statistically by ANOVA which showed a significant differences (p<0.05) in the groups V and VI of S.mutans and lactobacilli viability between counts and percentage killing of streptococci mutans and lactobacilli.10. All the groups Group II to Group VI were subjected tospectrophotometric analysis in time interval of ½ hour and the Optical Density values were measured where an initial decrease in optical density was noted.11. After irradiation, samples from group I to VI were subjected to ESEM analysis. ESEM observation of the residual dentin showed a significant reduction of bacteria deposited on the dentinal surface.CONCLUSION:Owing to the emergence of antibiotic resistance,photodynamic therapy has become a viable alternative therapy for biofilm related diseases such as dental caries. The advantages ofphotodynamic therapy over conventional antimicrobial agents are first, rapid killing of target organism depending mainly on the light energy dose delivered and therefore the power output of the light source used.Hence, resistance development would be unlikely as killing is mediated by singlet oxygen and free radicals and high concentration of photosensitizer do not need to be maintained in the disease site for more than a few minutes, in contrast with hours or even days necessary in the case of conventional antimicrobial agents. Finally, antimicrobial effects can be confined to the site of the lesion by careful topical application of photosensitizer and the area of irradiation can be restricted further by using an optical fibre.The results of this experimental investigation showed thatLED light in the presence of TB-O would be an effective approach against dental plaque -related diseases. Another new application of this study is the use of nanoparticles in a combined therapy approach that combines radiation therapy with PDT, a technique called self-lighting photodynamic therapy (SLPDT). Taken together, the studies discussed here suggest that this novel approach is promising and might represent a new direction in the near future. It should be noted that nanoparticlebased PDT is still in its infancy and much remains to be learned. This represents the most innovative approach that entails the up conversion of nanoparticles which are able to convert low-energy radiation to higher-energy emissions, thereby enabling PDT in deep tissues.This study has again demonstrated a superior bactericidaleffect of silver nano particles against organisms in conjunction with LED laser irradiation would be an effective protocol against pathogens like S.mutans and L.acidophilus that may resist many antimicrobial agents.Much work still needs to be done as very few clinicalstudies have evaluated the effect of the different delivery systems in terms of clinical efficiency and for application purposes. Beyond the laboratory Petridish, this technology still needs answers like appropriate dosage, delivery systems and exposure times that maximize clinical effectiveness while minimizing side effects." @default.
• W2894522694 created "2018-10-05" @default.
• W2894522694 creator A5069948457 @default.
• W2894522694 date "2010-03-01" @default.
• W2894522694 modified "2023-09-27" @default.
• W2894522694 title "Comparative Evaluation of Antimicrobial Action of Photodynamic Disinfection, Dyes and Nanosilver against Streptococcus Mutans and Lactobacillus Acidophillus on Coronal Dentin: An In Vitro Study" @default.
• W2894522694 hasPublicationYear "2010" @default.
• W2894522694 type Work @default.
• W2894522694 sameAs 2894522694 @default.
• W2894522694 citedByCount "0" @default.
• W2894522694 crossrefType "dissertation" @default.
• W2894522694 hasAuthorship W2894522694A5069948457 @default.
• W2894522694 hasConcept C100544194 @default.
• W2894522694 hasConcept C13965031 @default.
• W2894522694 hasConcept C178790620 @default.
• W2894522694 hasConcept C185592680 @default.
• W2894522694 hasConcept C192285135 @default.
• W2894522694 hasConcept C199343813 @default.
• W2894522694 hasConcept C2777221637 @default.
• W2894522694 hasConcept C2778430296 @default.
• W2894522694 hasConcept C2779263046 @default.
• W2894522694 hasConcept C2780206646 @default.
• W2894522694 hasConcept C2780255968 @default.
• W2894522694 hasConcept C2781323092 @default.
• W2894522694 hasConcept C31903555 @default.
• W2894522694 hasConcept C4937899 @default.
• W2894522694 hasConcept C523546767 @default.
• W2894522694 hasConcept C54355233 @default.
• W2894522694 hasConcept C58123911 @default.
• W2894522694 hasConcept C71924100 @default.
• W2894522694 hasConcept C86803240 @default.
• W2894522694 hasConcept C89423630 @default.
• W2894522694 hasConceptScore W2894522694C100544194 @default.
• W2894522694 hasConceptScore W2894522694C13965031 @default.
• W2894522694 hasConceptScore W2894522694C178790620 @default.
• W2894522694 hasConceptScore W2894522694C185592680 @default.
• W2894522694 hasConceptScore W2894522694C192285135 @default.
• W2894522694 hasConceptScore W2894522694C199343813 @default.
• W2894522694 hasConceptScore W2894522694C2777221637 @default.
• W2894522694 hasConceptScore W2894522694C2778430296 @default.
• W2894522694 hasConceptScore W2894522694C2779263046 @default.
• W2894522694 hasConceptScore W2894522694C2780206646 @default.
• W2894522694 hasConceptScore W2894522694C2780255968 @default.
• W2894522694 hasConceptScore W2894522694C2781323092 @default.
• W2894522694 hasConceptScore W2894522694C31903555 @default.
• W2894522694 hasConceptScore W2894522694C4937899 @default.
• W2894522694 hasConceptScore W2894522694C523546767 @default.
• W2894522694 hasConceptScore W2894522694C54355233 @default.
• W2894522694 hasConceptScore W2894522694C58123911 @default.
• W2894522694 hasConceptScore W2894522694C71924100 @default.
• W2894522694 hasConceptScore W2894522694C86803240 @default.
• W2894522694 hasConceptScore W2894522694C89423630 @default.
• W2894522694 hasLocation W28945226941 @default.
• W2894522694 hasOpenAccess W2894522694 @default.
• W2894522694 hasPrimaryLocation W28945226941 @default.
• W2894522694 hasRelatedWork W1736413848 @default.
• W2894522694 hasRelatedWork W1754498230 @default.
• W2894522694 hasRelatedWork W2007971954 @default.
• W2894522694 hasRelatedWork W2080079627 @default.
• W2894522694 hasRelatedWork W2147471905 @default.
• W2894522694 hasRelatedWork W2225614439 @default.
• W2894522694 hasRelatedWork W2342942675 @default.
• W2894522694 hasRelatedWork W2548479624 @default.
• W2894522694 hasRelatedWork W2626122343 @default.
• W2894522694 hasRelatedWork W2884881128 @default.
• W2894522694 hasRelatedWork W2925250669 @default.
• W2894522694 hasRelatedWork W2952784872 @default.
• W2894522694 hasRelatedWork W2957314797 @default.
• W2894522694 hasRelatedWork W2992990956 @default.
• W2894522694 hasRelatedWork W3037123806 @default.
• W2894522694 hasRelatedWork W3040205062 @default.
• W2894522694 hasRelatedWork W3119117220 @default.
• W2894522694 hasRelatedWork W3194315520 @default.
• W2894522694 hasRelatedWork W3194517400 @default.
• W2894522694 hasRelatedWork W99437670 @default.
• W2894522694 isParatext "false" @default.
• W2894522694 isRetracted "false" @default.
• W2894522694 magId "2894522694" @default.
• W2894522694 workType "dissertation" @default.