FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894529733> ?p ?o ?g. }

• W2894529733 endingPage "158" @default.
• W2894529733 startingPage "150" @default.
• W2894529733 abstract "Restoring and controlling fluid volume homeostasis is still a challenge in contemporary end-stage kidney disease patients treated by intermittent hemodialysis (HD) or hemodiafiltration (HDF). This primary target is achieved by ultrafiltration (dry weight probing) and control of intradialytic sodium transfer (dialysate-plasma Na gradient). The latter task is mostly ignored in clinical practice by applying a dialysate sodium prescription uniform for all patients of the dialysis center but unaligned to individual plasma sodium levels. Depending on the patient's natremia, a positive gradient gives rise to intradialytic diffusive sodium load and postdialytic thirst. On the contrary, a negative gradient may cause unwanted diffusive sodium removal and intradialytic symptoms. To overcome these challenges, a new conductivity-based electrolyte balancing algorithm embedded in a hemodialysis machine with the aim to achieve zero diffusive sodium balance in HD and online HDF treatments was tested in the form of a prospective clinical trial. The study comprised two phases: a first phase with a conventional fixed-sodium dialysate (standard care phase), followed by a phase with the electrolyte balancing control (EBC) module activated (controlled care phase). The results show a reduction in the variability of the intradialytic plasma sodium concentration shift, but it is overlain by a small but statistically significant increase in the mean plasma sodium levels. However, no clinical manifestations were observed. This sodium load can be explained by the design of the algorithm based on dialysate conductivity instead of sodium concentration. Furthermore, the increase in plasma sodium can be corrected by taking into account the potassium shift during the treatment. This study showed that the EBC module incorporated in the HD machine is able to automatically individualize the dialysate sodium to the patient's plasma sodium without measuring or calculating predialytic plasma levels from previous laboratory tests. This tool has the potential to facilitate fluid management, to control diffusive sodium flux, and to improve intradialytic tolerance in daily clinical practice." @default.
• W2894529733 created "2018-10-05" @default.
• W2894529733 creator A5037222823 @default.
• W2894529733 creator A5054201980 @default.
• W2894529733 creator A5070981529 @default.
• W2894529733 creator A5073605405 @default.
• W2894529733 creator A5075863188 @default.
• W2894529733 date "2018-09-27" @default.
• W2894529733 modified "2023-09-26" @default.
• W2894529733 title "Zero Diffusive Sodium Balance in Hemodialysis Provided by an Algorithm‐Based Electrolyte Balancing Controller: A Proof of Principle Clinical Study" @default.
• W2894529733 cites W1498122249 @default.
• W2894529733 cites W1523252251 @default.
• W2894529733 cites W1602938249 @default.
• W2894529733 cites W1979269288 @default.
• W2894529733 cites W1984797688 @default.
• W2894529733 cites W1984803148 @default.
• W2894529733 cites W2001197789 @default.
• W2894529733 cites W2016165834 @default.
• W2894529733 cites W2017147631 @default.
• W2894529733 cites W2044514269 @default.
• W2894529733 cites W2058032666 @default.
• W2894529733 cites W2063671161 @default.
• W2894529733 cites W2069412243 @default.
• W2894529733 cites W2082525414 @default.
• W2894529733 cites W2105379431 @default.
• W2894529733 cites W2111654578 @default.
• W2894529733 cites W2126202171 @default.
• W2894529733 cites W2135305196 @default.
• W2894529733 cites W2228943834 @default.
• W2894529733 cites W2316088696 @default.
• W2894529733 cites W2624293444 @default.
• W2894529733 cites W2734034680 @default.
• W2894529733 cites W2742386908 @default.
• W2894529733 cites W2802593240 @default.
• W2894529733 cites W50034755 @default.
• W2894529733 doi "https://doi.org/10.1111/aor.13328" @default.
• W2894529733 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30260035" @default.
• W2894529733 hasPublicationYear "2018" @default.
• W2894529733 type Work @default.
• W2894529733 sameAs 2894529733 @default.
• W2894529733 citedByCount "30" @default.
• W2894529733 countsByYear W28945297332018 @default.
• W2894529733 countsByYear W28945297332019 @default.
• W2894529733 countsByYear W28945297332020 @default.
• W2894529733 countsByYear W28945297332021 @default.
• W2894529733 countsByYear W28945297332022 @default.
• W2894529733 countsByYear W28945297332023 @default.
• W2894529733 crossrefType "journal-article" @default.
• W2894529733 hasAuthorship W2894529733A5037222823 @default.
• W2894529733 hasAuthorship W2894529733A5054201980 @default.
• W2894529733 hasAuthorship W2894529733A5070981529 @default.
• W2894529733 hasAuthorship W2894529733A5073605405 @default.
• W2894529733 hasAuthorship W2894529733A5075863188 @default.
• W2894529733 hasConcept C126322002 @default.
• W2894529733 hasConcept C147789679 @default.
• W2894529733 hasConcept C17525397 @default.
• W2894529733 hasConcept C178790620 @default.
• W2894529733 hasConcept C185592680 @default.
• W2894529733 hasConcept C2778063415 @default.
• W2894529733 hasConcept C2779978075 @default.
• W2894529733 hasConcept C537181965 @default.
• W2894529733 hasConcept C68801617 @default.
• W2894529733 hasConcept C71924100 @default.
• W2894529733 hasConceptScore W2894529733C126322002 @default.
• W2894529733 hasConceptScore W2894529733C147789679 @default.
• W2894529733 hasConceptScore W2894529733C17525397 @default.
• W2894529733 hasConceptScore W2894529733C178790620 @default.
• W2894529733 hasConceptScore W2894529733C185592680 @default.
• W2894529733 hasConceptScore W2894529733C2778063415 @default.
• W2894529733 hasConceptScore W2894529733C2779978075 @default.
• W2894529733 hasConceptScore W2894529733C537181965 @default.
• W2894529733 hasConceptScore W2894529733C68801617 @default.
• W2894529733 hasConceptScore W2894529733C71924100 @default.
• W2894529733 hasIssue "2" @default.
• W2894529733 hasLocation W28945297331 @default.
• W2894529733 hasLocation W28945297332 @default.
• W2894529733 hasOpenAccess W2894529733 @default.
• W2894529733 hasPrimaryLocation W28945297331 @default.
• W2894529733 hasRelatedWork W1976422963 @default.
• W2894529733 hasRelatedWork W2168410092 @default.
• W2894529733 hasRelatedWork W2351807067 @default.
• W2894529733 hasRelatedWork W2361205819 @default.
• W2894529733 hasRelatedWork W2362097515 @default.
• W2894529733 hasRelatedWork W2399754157 @default.
• W2894529733 hasRelatedWork W2569223942 @default.
• W2894529733 hasRelatedWork W3031360451 @default.
• W2894529733 hasRelatedWork W4229012474 @default.
• W2894529733 hasRelatedWork W60322883 @default.
• W2894529733 hasVolume "43" @default.
• W2894529733 isParatext "false" @default.
• W2894529733 isRetracted "false" @default.
• W2894529733 magId "2894529733" @default.
• W2894529733 workType "article" @default.