FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894565004> ?p ?o ?g. }

• W2894565004 endingPage "333" @default.
• W2894565004 startingPage "327" @default.
• W2894565004 abstract "Abstract Point-of-care testing devices for companion diagnostic applications is a growing area in immunobiosensor technology. With the widespread diffusion of smartphones and improved enclosed photocamera technology, fast and accurate point-of-care diagnosis could be developed for delivering optical biosensing abilities to the general population. Herein, we propose a smartphone-based immunosensor employing a paper-based format coupled with thermochemiluminescence (TCL) detection, that was optimized for valproic acid (VPA) detection in blood and saliva samples. TCL is a chemical luminescence phenomenon in which photons are emitted upon thermally-induced fragmentation of a suitable molecule, with production of a moiety in its singlet electronically excited state. The latter emits a photon while decaying to its ground state. TCL peculiar characteristics combine high detectability and reagent-less nature of the measurement. A one-step competitive immunoassay for VPA detection based on vertical flow immunoassay (VFIA) format was developed, employing silica nanoparticles doped with a TCL 1,2-dioxetane derivative as a label. The VFIA sensor is a stack of paper-based layers functionalized with reagents stored in a stable form, allowing to complete the test in 12 min simply upon sample addition. By 3D printing, simple accessories were produced to turn a smartphone into a biosensing device that provides a power source for the heat shock required to trigger the TCL reaction and a sensitive camera for measuring emitted photons. The developed biosensor allowed VPA detection in blood and saliva, with limits of detection (4 and 0.05 μg mL−1 respectively) and dynamic ranges (4–300 and 0.05–20 μg mL-1) suitable for therapeutic drug monitoring. The integrated device offers an innovative analytical platform for rapid one-step biosensors exploitable in a variety of point-of-care applications." @default.
• W2894565004 created "2018-10-12" @default.
• W2894565004 creator A5000028774 @default.
• W2894565004 creator A5002377182 @default.
• W2894565004 creator A5003560823 @default.
• W2894565004 creator A5033420164 @default.
• W2894565004 creator A5044156561 @default.
• W2894565004 creator A5049469105 @default.
• W2894565004 creator A5053747856 @default.
• W2894565004 creator A5079187267 @default.
• W2894565004 creator A5082284122 @default.
• W2894565004 date "2019-01-01" @default.
• W2894565004 modified "2023-10-02" @default.
• W2894565004 title "A simple smartphone-based thermochemiluminescent immunosensor for valproic acid detection using 1,2-dioxetane analogue-doped nanoparticles as a label" @default.
• W2894565004 cites W1595044094 @default.
• W2894565004 cites W1947554696 @default.
• W2894565004 cites W1964798298 @default.
• W2894565004 cites W1970973153 @default.
• W2894565004 cites W1982559826 @default.
• W2894565004 cites W2024823919 @default.
• W2894565004 cites W2043280947 @default.
• W2894565004 cites W2044103025 @default.
• W2894565004 cites W2050249993 @default.
• W2894565004 cites W2059361881 @default.
• W2894565004 cites W2080173526 @default.
• W2894565004 cites W2081073783 @default.
• W2894565004 cites W2089402359 @default.
• W2894565004 cites W2095513042 @default.
• W2894565004 cites W2169114399 @default.
• W2894565004 cites W2188285942 @default.
• W2894565004 cites W2312862153 @default.
• W2894565004 cites W2320235882 @default.
• W2894565004 cites W2326398818 @default.
• W2894565004 cites W2544147359 @default.
• W2894565004 cites W2558097459 @default.
• W2894565004 cites W2567921357 @default.
• W2894565004 cites W2593215007 @default.
• W2894565004 cites W2611321798 @default.
• W2894565004 cites W2759124874 @default.
• W2894565004 cites W2763277368 @default.
• W2894565004 cites W2766741612 @default.
• W2894565004 cites W2767229647 @default.
• W2894565004 cites W591922936 @default.
• W2894565004 doi "https://doi.org/10.1016/j.snb.2018.10.012" @default.
• W2894565004 hasPublicationYear "2019" @default.
• W2894565004 type Work @default.
• W2894565004 sameAs 2894565004 @default.
• W2894565004 citedByCount "34" @default.
• W2894565004 countsByYear W28945650042019 @default.
• W2894565004 countsByYear W28945650042020 @default.
• W2894565004 countsByYear W28945650042021 @default.
• W2894565004 countsByYear W28945650042022 @default.
• W2894565004 countsByYear W28945650042023 @default.
• W2894565004 crossrefType "journal-article" @default.
• W2894565004 hasAuthorship W2894565004A5000028774 @default.
• W2894565004 hasAuthorship W2894565004A5002377182 @default.
• W2894565004 hasAuthorship W2894565004A5003560823 @default.
• W2894565004 hasAuthorship W2894565004A5033420164 @default.
• W2894565004 hasAuthorship W2894565004A5044156561 @default.
• W2894565004 hasAuthorship W2894565004A5049469105 @default.
• W2894565004 hasAuthorship W2894565004A5053747856 @default.
• W2894565004 hasAuthorship W2894565004A5079187267 @default.
• W2894565004 hasAuthorship W2894565004A5082284122 @default.
• W2894565004 hasConcept C111472728 @default.
• W2894565004 hasConcept C138885662 @default.
• W2894565004 hasConcept C155672457 @default.
• W2894565004 hasConcept C15744967 @default.
• W2894565004 hasConcept C169760540 @default.
• W2894565004 hasConcept C171250308 @default.
• W2894565004 hasConcept C185592680 @default.
• W2894565004 hasConcept C192562407 @default.
• W2894565004 hasConcept C2777172819 @default.
• W2894565004 hasConcept C2778186239 @default.
• W2894565004 hasConcept C2780586882 @default.
• W2894565004 hasConcept C43617362 @default.
• W2894565004 hasConceptScore W2894565004C111472728 @default.
• W2894565004 hasConceptScore W2894565004C138885662 @default.
• W2894565004 hasConceptScore W2894565004C155672457 @default.
• W2894565004 hasConceptScore W2894565004C15744967 @default.
• W2894565004 hasConceptScore W2894565004C169760540 @default.
• W2894565004 hasConceptScore W2894565004C171250308 @default.
• W2894565004 hasConceptScore W2894565004C185592680 @default.
• W2894565004 hasConceptScore W2894565004C192562407 @default.
• W2894565004 hasConceptScore W2894565004C2777172819 @default.
• W2894565004 hasConceptScore W2894565004C2778186239 @default.
• W2894565004 hasConceptScore W2894565004C2780586882 @default.
• W2894565004 hasConceptScore W2894565004C43617362 @default.
• W2894565004 hasLocation W28945650041 @default.
• W2894565004 hasOpenAccess W2894565004 @default.
• W2894565004 hasPrimaryLocation W28945650041 @default.
• W2894565004 hasRelatedWork W1066196250 @default.
• W2894565004 hasRelatedWork W1976195758 @default.
• W2894565004 hasRelatedWork W2275341195 @default.
• W2894565004 hasRelatedWork W2314971351 @default.
• W2894565004 hasRelatedWork W2354742956 @default.
• W2894565004 hasRelatedWork W2518360665 @default.
• W2894565004 hasRelatedWork W2899084033 @default.
• W2894565004 hasRelatedWork W3016721682 @default.

• next