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- W2894568994 abstract "Introduction: Tranjugular intrahepatic portosystemic shunt (TIPS) has became increasingly relevant in controlling recurrent variceal bleeding and intractable ascites in patients with portal hypertension due to advanced liver cirrhosis. Complications and success rate seem to be related to the pre-procedure conditions of the patients. The endopoints of this study are to value outcome of patients with variceal bleeding and ascites. Methods: Between 2013 and 2017, 41 patients with mean age 58.6 ± 10.9 years, underwent TIPS. Indications were variceal bleeding in 20 patients, ascites in 19 patients, both in 1 and post-LT (liver transplantation) in 1 patient; in 3 patients the procedures were subsequent to LT and in other 10 patients were carried out as bridge to LT. Clinical status was assessed according to the model of end-stage liver disease (MELD), pre and post-TIPS gradient pressure were measured, as well as ammonemia level. Outcome was valued assessing recurrence of bleeding or ascites and survival. Results: Pre and post-TIPS comparison showed a statistically significant reduction in portal pressure gradient (18.4 vs 10.5 mmHg) with an increase in ammonemia level (49.4 vs 59.5 μmol/L) without clinical syptoms; however no differences were observed in MELD (13.8 vs 14.3). Bleeding and ascites recurred in 4 out of 21 patients and in 14 out of 20 patients, respectively. Encephalopathy was present in 11 patients. Overall actuarial survival was 82%, 74% and 47% at 6, 12 and 24 months, respectively. Conclusion: TIPS seems to reduce more efficacy the risk of bleeding than ascites without modifying liver function." @default.
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- W2894568994 date "2018-09-01" @default.
- W2894568994 modified "2023-09-27" @default.
- W2894568994 title "Does tranjugular intrahepatic portosystemic shunt in refractory ascites and variceal re-bleeding guarantee same successful results?" @default.
- W2894568994 doi "https://doi.org/10.1016/j.hpb.2018.06.2979" @default.
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