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- W2894571372 abstract "Abstract Introduction Curative radiotherapy is guideline treatment for inoperable patients of good performance status with Stage I & II Non‐Small Cell Lung Cancer ( NSCLC ). The aim of this study was to evaluate radiotherapy patterns of care in these patients, the reasons for palliative treatment and the proportion of patients suitable for curative stereotactic ablative body radiotherapy ( SABR ). Methods Electronic oncology databases at three institutions were queried to retrieve data on patients with inoperable Stage I & II NSCLC seen in radiation oncology clinics between 1/1/2008 and 31/12/2014. Suitability for SABR was defined as peripheral tumours less than 5 cm in size. Factors associated with curative treatment were determined using univariate and multivariate analyses. Results Three‐hundred‐and‐twelve patients were identified of whom 178 (57%) received curative radiotherapy, 58 (19%) palliative radiotherapy and 76 (24%) no radiotherapy. The main reason for receiving palliative rather than curative treatment was COPD or poor pulmonary function (26%). Method of diagnosis ( P = 0.031), Simplified Comorbidity Score ( P = 0.003), ECOG performance status ( P = 0.016), FEV 1% ( P = 0.040), treating institution ( P < 0.0001) and time period ( P = 0.016) were associated with curative radiotherapy on multivariate analysis. In patients with T1‐2N0M0 NSCLC , 19 (31%) who did not receive treatment and 7 (21%) who underwent palliative radiotherapy were technically and clinically suitable for SABR . Conclusion Only 57% of patients with Stage I‐ II NSCLC were treated with curative radiotherapy. Patient factors were the predominant reason for palliative treatment, however, treating institution also played a role. A considerable proportion of patients who underwent palliative or no radiotherapy were suitable for SABR treatment." @default.
- W2894571372 created "2018-10-12" @default.
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- W2894571372 date "2018-10-03" @default.
- W2894571372 modified "2023-10-14" @default.
- W2894571372 title "Radiotherapy patterns of care for stage I and <scp>II</scp> non‐small cell lung cancer in Sydney, Australia" @default.
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- W2894571372 doi "https://doi.org/10.1111/1754-9485.12819" @default.
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