Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894596217> ?p ?o ?g. }
Showing items 1 to 60 of
60
with 100 items per page.
- W2894596217 abstract "Pain sensation is variable both in animals and humans. Factors that influence the threshold and intensity of pain include race, ethnic origin, sex, material standard of living, stress exposure, environmental conditions and genetic factors. Methods used to identify potential gene variants responsible for the development of pain syndromes include identification of mutation or single nucleotide polymorphism (SNP), analysis of genetic variability in twins, and recently, genome wide association study (GWAS). Pain sensation disorders are the result of a single mutation, as in Biemond syndrome (congenital analgesia), erythromelalgia and paroxysmal extreme pain disorder, or polygenic mutations, as in fibromyalgia and migraine. Sensation of pain starts when the stimulus acts through chemical mediators to activate nerve endings. The signal is then transduced through neurons and spinal pathways to the brain. This process involves synaptic neurotransmitters, membrane receptors, neuromodulators and cell structures that ultimately affect the intensity of pain. The objective of this paper is to present selected clinical syndromes of genetically determined pain sensation disorders and the use of genetic diagnostics in explaining their cause." @default.
- W2894596217 created "2018-10-12" @default.
- W2894596217 creator A5019961066 @default.
- W2894596217 creator A5020838417 @default.
- W2894596217 creator A5062787145 @default.
- W2894596217 creator A5066124138 @default.
- W2894596217 date "2018-05-31" @default.
- W2894596217 modified "2023-09-27" @default.
- W2894596217 title "Selected clinical syndromes of genetic variability in pain sensation" @default.
- W2894596217 doi "https://doi.org/10.5604/01.3001.0012.5927" @default.
- W2894596217 hasPublicationYear "2018" @default.
- W2894596217 type Work @default.
- W2894596217 sameAs 2894596217 @default.
- W2894596217 citedByCount "0" @default.
- W2894596217 crossrefType "journal-article" @default.
- W2894596217 hasAuthorship W2894596217A5019961066 @default.
- W2894596217 hasAuthorship W2894596217A5020838417 @default.
- W2894596217 hasAuthorship W2894596217A5062787145 @default.
- W2894596217 hasAuthorship W2894596217A5066124138 @default.
- W2894596217 hasConcept C130093455 @default.
- W2894596217 hasConcept C15744967 @default.
- W2894596217 hasConcept C180747234 @default.
- W2894596217 hasConcept C3020300999 @default.
- W2894596217 hasConcept C42219234 @default.
- W2894596217 hasConcept C71924100 @default.
- W2894596217 hasConcept C99508421 @default.
- W2894596217 hasConceptScore W2894596217C130093455 @default.
- W2894596217 hasConceptScore W2894596217C15744967 @default.
- W2894596217 hasConceptScore W2894596217C180747234 @default.
- W2894596217 hasConceptScore W2894596217C3020300999 @default.
- W2894596217 hasConceptScore W2894596217C42219234 @default.
- W2894596217 hasConceptScore W2894596217C71924100 @default.
- W2894596217 hasConceptScore W2894596217C99508421 @default.
- W2894596217 hasLocation W28945962171 @default.
- W2894596217 hasOpenAccess W2894596217 @default.
- W2894596217 hasPrimaryLocation W28945962171 @default.
- W2894596217 hasRelatedWork W1510070310 @default.
- W2894596217 hasRelatedWork W1937484232 @default.
- W2894596217 hasRelatedWork W1989743124 @default.
- W2894596217 hasRelatedWork W2017196515 @default.
- W2894596217 hasRelatedWork W2025332538 @default.
- W2894596217 hasRelatedWork W2070736706 @default.
- W2894596217 hasRelatedWork W2158456401 @default.
- W2894596217 hasRelatedWork W2180963381 @default.
- W2894596217 hasRelatedWork W2395708929 @default.
- W2894596217 hasRelatedWork W2399292885 @default.
- W2894596217 hasRelatedWork W2413839238 @default.
- W2894596217 hasRelatedWork W2416662241 @default.
- W2894596217 hasRelatedWork W2804551689 @default.
- W2894596217 hasRelatedWork W3048185429 @default.
- W2894596217 hasRelatedWork W3090535938 @default.
- W2894596217 hasRelatedWork W3111795388 @default.
- W2894596217 hasRelatedWork W3165008909 @default.
- W2894596217 hasRelatedWork W3205207231 @default.
- W2894596217 hasRelatedWork W594048690 @default.
- W2894596217 hasRelatedWork W2141096511 @default.
- W2894596217 isParatext "false" @default.
- W2894596217 isRetracted "false" @default.
- W2894596217 magId "2894596217" @default.
- W2894596217 workType "article" @default.