FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2894611590> ?p ?o ?g. }

• W2894611590 abstract "The circumlimbal suture is a technique for inducing experimental glaucoma in rodents by chronically elevating intraocular pressure (IOP), a well-known risk factor for glaucoma. This protocol demonstrates a step-by-step guide on this technique in Long Evans rats and C57BL/6 mice. Under general anesthesia, a purse-string suture is applied on the conjunctiva, around the equator and behind the limbus of the eye. The fellow eye serves as an untreated control. Over the duration of our study, which was a period of 8 weeks for rats and 12 weeks for mice, IOP remained elevated, as measured regularly by rebound tonometry in conscious animals without topical anesthesia. In both species, the sutured eyes showed electroretinogram features consistent with preferential inner retinal dysfunction. Optical coherence tomography showed selective thinning of the retinal nerve fiber layer. Histology of the rat retina in cross-section found reduced cell density in the ganglion cell layer, but no change in other cellular layers. Staining of flat-mounted mouse retinae with a ganglion cell specific marker (RBPMS) confirmed ganglion cell loss. The circumlimbal suture is a simple, minimally invasive and cost-effective way to induce ocular hypertension that leads to ganglion cell injury in both rats and mice." @default.
• W2894611590 created "2018-10-12" @default.
• W2894611590 creator A5007496411 @default.
• W2894611590 creator A5007706989 @default.
• W2894611590 creator A5033455416 @default.
• W2894611590 creator A5043108043 @default.
• W2894611590 creator A5045196153 @default.
• W2894611590 creator A5086332372 @default.
• W2894611590 creator A5086701746 @default.
• W2894611590 date "2018-10-05" @default.
• W2894611590 modified "2023-09-26" @default.
• W2894611590 title "A Model of Glaucoma Induced by Circumlimbal Suture in Rats and Mice" @default.
• W2894611590 cites W1479957045 @default.
• W2894611590 cites W191867948 @default.
• W2894611590 cites W1960721561 @default.
• W2894611590 cites W1969772753 @default.
• W2894611590 cites W1987421719 @default.
• W2894611590 cites W2002319579 @default.
• W2894611590 cites W2004313303 @default.
• W2894611590 cites W2005174791 @default.
• W2894611590 cites W2017105083 @default.
• W2894611590 cites W2035029504 @default.
• W2894611590 cites W2039127036 @default.
• W2894611590 cites W2052840578 @default.
• W2894611590 cites W2056166545 @default.
• W2894611590 cites W2084081191 @default.
• W2894611590 cites W2131142443 @default.
• W2894611590 cites W2303421496 @default.
• W2894611590 cites W2329089869 @default.
• W2894611590 cites W2461414543 @default.
• W2894611590 cites W2527723788 @default.
• W2894611590 cites W2535880877 @default.
• W2894611590 cites W2581511798 @default.
• W2894611590 cites W2587089844 @default.
• W2894611590 cites W2773966245 @default.
• W2894611590 cites W2800552274 @default.
• W2894611590 cites W175053877 @default.
• W2894611590 doi "https://doi.org/10.3791/58287" @default.
• W2894611590 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6235421" @default.
• W2894611590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30346390" @default.
• W2894611590 hasPublicationYear "2018" @default.
• W2894611590 type Work @default.
• W2894611590 sameAs 2894611590 @default.
• W2894611590 citedByCount "5" @default.
• W2894611590 countsByYear W28946115902018 @default.
• W2894611590 countsByYear W28946115902021 @default.
• W2894611590 countsByYear W28946115902023 @default.
• W2894611590 crossrefType "journal-article" @default.
• W2894611590 hasAuthorship W2894611590A5007496411 @default.
• W2894611590 hasAuthorship W2894611590A5007706989 @default.
• W2894611590 hasAuthorship W2894611590A5033455416 @default.
• W2894611590 hasAuthorship W2894611590A5043108043 @default.
• W2894611590 hasAuthorship W2894611590A5045196153 @default.
• W2894611590 hasAuthorship W2894611590A5086332372 @default.
• W2894611590 hasAuthorship W2894611590A5086701746 @default.
• W2894611590 hasBestOaLocation W28946115902 @default.
• W2894611590 hasConcept C105702510 @default.
• W2894611590 hasConcept C118487528 @default.
• W2894611590 hasConcept C169760540 @default.
• W2894611590 hasConcept C2776521421 @default.
• W2894611590 hasConcept C2777093970 @default.
• W2894611590 hasConcept C2777327002 @default.
• W2894611590 hasConcept C2777624874 @default.
• W2894611590 hasConcept C2778527774 @default.
• W2894611590 hasConcept C2780188069 @default.
• W2894611590 hasConcept C2780592520 @default.
• W2894611590 hasConcept C2780827179 @default.
• W2894611590 hasConcept C2781092963 @default.
• W2894611590 hasConcept C2781099447 @default.
• W2894611590 hasConcept C2781334511 @default.
• W2894611590 hasConcept C71924100 @default.
• W2894611590 hasConcept C86803240 @default.
• W2894611590 hasConceptScore W2894611590C105702510 @default.
• W2894611590 hasConceptScore W2894611590C118487528 @default.
• W2894611590 hasConceptScore W2894611590C169760540 @default.
• W2894611590 hasConceptScore W2894611590C2776521421 @default.
• W2894611590 hasConceptScore W2894611590C2777093970 @default.
• W2894611590 hasConceptScore W2894611590C2777327002 @default.
• W2894611590 hasConceptScore W2894611590C2777624874 @default.
• W2894611590 hasConceptScore W2894611590C2778527774 @default.
• W2894611590 hasConceptScore W2894611590C2780188069 @default.
• W2894611590 hasConceptScore W2894611590C2780592520 @default.
• W2894611590 hasConceptScore W2894611590C2780827179 @default.
• W2894611590 hasConceptScore W2894611590C2781092963 @default.
• W2894611590 hasConceptScore W2894611590C2781099447 @default.
• W2894611590 hasConceptScore W2894611590C2781334511 @default.
• W2894611590 hasConceptScore W2894611590C71924100 @default.
• W2894611590 hasConceptScore W2894611590C86803240 @default.
• W2894611590 hasIssue "140" @default.
• W2894611590 hasLocation W28946115901 @default.
• W2894611590 hasLocation W28946115902 @default.
• W2894611590 hasLocation W28946115903 @default.
• W2894611590 hasOpenAccess W2894611590 @default.
• W2894611590 hasPrimaryLocation W28946115901 @default.
• W2894611590 hasRelatedWork W2080262026 @default.
• W2894611590 hasRelatedWork W2085051551 @default.
• W2894611590 hasRelatedWork W2216422604 @default.
• W2894611590 hasRelatedWork W2219931365 @default.
• W2894611590 hasRelatedWork W2796476988 @default.
• W2894611590 hasRelatedWork W2802927435 @default.

• next